Results 71 to 80 of about 63,544 (259)

A vaccinia virus renaissanceNew vaccine and immunotherapeutic uses after smallpox eradication

open access: yesHuman Vaccines & Immunotherapeutics, 2012
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi   +2 more
doaj   +1 more source

“Remarkable solutions to impossible problems”: lessons for malaria from the eradication of smallpox

open access: yesMalaria Journal, 2019
Malaria elimination and eventual eradication will require internationally coordinated approaches; sustained engagement from politicians, communities, and funders; efficient organizational structures; innovation and new tools; and well-managed programmes.
Justin M. Cohen
semanticscholar   +1 more source

Public health reforms and the mortality decline in nineteenth‐century Italy

open access: yesThe Economic History Review, EarlyView.
Abstract This study examines the impact of Italy's 1887–8 health reforms on mortality, contributing to the historical debate on the state's role in Europe's health transition. Leveraging event‐study‐style difference‐in‐differences approach, we assess the effectiveness of the Crispi–Pagliani reforms, which strengthened public health governance and ...
Francesco Maria Salvatore Fiore Melacrinis   +1 more
wiley   +1 more source

Analysis of aerobiological studies with orthopoxviruses by U.S. Department of Defense

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Discontinuation of vaccination after the completion of Smallpox global eradication program led to a sharp decrease in the level of collective immunity not only to smallpox but also to other orthopoxvirus infections.
Gennady G. Onishenko   +4 more
doaj   +1 more source

Evidence for Residual Immunity to Smallpox After Vaccination and Implications for Re-emergence.

open access: yesMilitary Medicine, 2019
INTRODUCTION Smallpox has been eradicated but advances in synthetic biology have increased the risk of its re-emergence. Residual immunity in individuals who were previously vaccinated may mitigate the impact of an outbreak, but there is a high degree of
M. Kunasekaran   +4 more
semanticscholar   +1 more source

A guide to heat shock factors as multifunctional transcriptional regulators

open access: yesThe FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka   +3 more
wiley   +1 more source

Vaccinations against smallpox and tuberculosis are associated with better long-term survival: a Danish case-cohort study 1971–2010

open access: yesInternational Journal of Epidemiology, 2016
Background: When vaccinations with vaccinia against smallpox and Bacillus Calmette-Guérin (BCG) against tuberculosis were phased out in some high-income countries around 1980, the impact on overall mortality was not examined.
A. Rieckmann   +8 more
semanticscholar   +1 more source

From local knowledge and science to policy: Lessons learned from Fiji's valuable grouper fisheries

open access: yesJournal of Fish Biology, EarlyView.
Abstract Pacific Island communities are heavily dependent on fisheries for subsistence and livelihoods. Yet, despite their importance, coastal fisheries are poorly managed and commercial pressures increasingly threaten them. Groupers (Epinephelidae) are exceptionally vulnerable to overexploitation due to aspects of their biology while their economic ...
Yvonne Sadovy de Mitcheson   +3 more
wiley   +1 more source

Evidence of Long-Distance Aerial Convection of Variola Virus and Implications for Disease Control

open access: yesViruses, 2019
Two distinct phenomena of airborne transmission of variola virus (smallpox) were described in the pre-eradication era—direct respiratory transmission, and a unique phenomenon of transmission over greater distances, referred to as “aerial ...
Chandini Raina MacIntyre   +4 more
doaj   +1 more source

SMALLPOX AND VACCINIA. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1907
In an experience with smallpox limited to the town of Colorado and occurring between the dates of April 7 and May 20, 1907, the following conditions were encountered. They are interesting as confirming previous observations as to the coincidence of variola and vaccinia.
openaire   +2 more sources

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