Results 31 to 40 of about 598,726 (234)
The article presents the results of research quality of drugs for the prevention of smallpox during the period from 2007 to 2015 years, where the reference standard uses industry standard of activity, specificity (identification) and necrotic activity of
A. V. Muhacheva+8 more
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Developing New Smallpox Vaccines
New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments.
Steven R. Rosenthal+3 more
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Risks and Benefits of Preexposure and Postexposure Smallpox Vaccination
This article presents a model and decision criteria for evaluating a person’s risk of pre- or postexposure smallpox vaccination in light of serious vaccine-related adverse events (death, postvaccine encephalitis and progressive vaccinia).
Martin I. Meltzer
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Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre+7 more
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Vaccines for preventing smallpox [PDF]
Smallpox was eradicated by 1980, but its possible use as a bioweapon has rekindled interest in the development of protective vaccines. Therefore, stockpiled calf lymph-derived vaccines and recently developed cell-cultured vaccines have been investigated to contribute information to smallpox emergency response plans, while newer (non-replication ...
Benjamin G Mordmueller+1 more
openaire +3 more sources
Mpox Outbreak: A Call for Urgent Action and Improved Response Strategies. [PDF]
ABSTRACT Introduction The resurgence of mpox presents a significant global public health challenge, especially in non‐endemic regions. Following its initial global spread in 2022, the current outbreak is driven by a newly emerged Clade I, exhibiting atypical clinical manifestations and altered transmission patterns.
Edward M+3 more
europepmc +2 more sources
The Pasteurian contribution to the history of vaccines
Vaccination, the transmission of “vaccine”, a benign disease of cows, to immunize human beings against smallpox, was invented by Jenner at the end of the eighteenth century.
Schwartz, Maxime
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A vaccinia virus renaissance
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi+2 more
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Evolution of means and principles of smallpox vaccination
There are several possible reasons for the return of smallpox as an endemic disease. For example, the possibility of maintaining smallpox virus in an active state in the corpses of the dead, buried in permafrost regions, or the evolutionary changes of ...
S. V. Borisevich+7 more
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Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam+6 more
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