Results 31 to 40 of about 18,095 (151)

Remaining Questions about Clinical Variola Major

Emerging Infectious Diseases, 2011
After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
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Phase-out of smallpox vaccination and the female/male HIV-1 prevalence ratio: an ecological study from Guinea-Bissau

BMJ Open, 2019
Objective In Guinea-Bissau, West Africa, we observed that having a smallpox vaccination scar was associated with lower HIV-1 prevalence, more strongly for women than men.
Marie Villumsen, Peter Aaby, Amabelia Rodrigues, Andreas Rieckmann, Christine Benn, Bo Langhoff Hønge, Signe Sørup, Zacarias Jose da Silva, Hilton Whittle   +8 more
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Serological Immunity to Smallpox in New South Wales, Australia

Viruses, 2020
The re-emergence of smallpox is an increasing and legitimate concern due to advances in synthetic biology. Vaccination programs against smallpox using the vaccinia virus vaccine ceased with the eradication of smallpox and, unlike many other countries ...
Valentina Costantino, Mallory J. Trent, John S. Sullivan, Mohana P. Kunasekaran, Richard Gray, Raina MacIntyre   +5 more
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Approaches to Reduce Adverse Effect of Vaccinia Virus in Orally Immunized Mice

Проблемы особо опасных инфекций, 2016
Objective of the investigation was to model the adverse action of vaccinia virus (VV), caused by oral immunization of mice and to evaluate efficacy of its reduction, using therapeutic and prophylactic drugs. Materials and methods.
D. O. Galakhova, Ar. A. Sergeev, E. V. Shevtsova, Al. A. Sergeev, A. S. Zamedyanskaya, K. A. Titova, L. N. Shishkina, L. E. Bulychev, S. V. Borisevich, V. N. Podkuiko, A. P. Pirozhkov, A. V. Koval’Chuk, Ya. V. Polyansky, E. Yu. Vakhnov, V. V. Perekrest, V. A. Shevtsov, A. P. Agafonov, A. N. Sergeev   +17 more
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Vaccinia virus-based vector against infectious diseases and tumors

Human Vaccines & Immunotherapeutics, 2021
Vaccinia virus was used to prevent smallpox. After the World Health Organization declared smallpox extinct, vaccinia virus has been explored for the development of vaccines against a variety of infectious diseases.
Ziling Zhang, Lanlan Dong, Chen Zhao, Peiyong Zheng, Xiaoyan Zhang, Jianqing Xu   +5 more
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Monkeypox in humans – the review

Journal of Education, Health and Sport, 2022
Monkeypox is an emerging zoonotic disease caused by the monkeypox virus with a presentation similar to smallpox. Being previously endemic to Africa, now the disease is spreading across the world, causing fear of a potential next pandemic.
Konrad Warchoł, Adam Jasiura , Kamila Giżewska, Aleksandra Wójcik , Sylwiusz Niedobylski   +4 more
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Preclinical Studies of the Specific Activity of the Live Culture Vaccine VACD6 against Smallpox and other Orthopoxvirus Infections

Эпидемиология и вакцинопрофилактика, 2023
Relevance. The epidemiological situation in the world is characterized by an increase in the incidence of orthopoxvirus infections in humans and animals.
S. N. Shchelkunov, S. N. Yakubitskiy, A. E. Nesterov, I. V. Kolosova, A. A. Sergeev, А. V. Zaykovskaya, A. S. Kabanov, Е. A. Nechaeva, M. P. Bogryantseva, S. V. Usova, N. S. Kutserubova, T. V. Tregubchak, E. V. Gavrilova, R. A. Maksyutov   +13 more
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Correlations between Humoral Immunity, Vaccination Period and Demographic Characteristics of First Immunized Smallpox Vaccine Recipients

Эпидемиология и вакцинопрофилактика, 2020
Relevance. After vaccination against smallpox is completed, more than 50% of the population are not immune to pathogens of the genus Orthopoxvirus, which creates the risk of mass infection if the smallpox virus is used as a biological weapon.Aim.
O. S. Ermilova, Z. I. Ghinko, V. A. Belyavskaya   +2 more
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TLR3 and TLR9 agonists improve postexposure vaccination efficacy of live smallpox vaccines. [PDF]

PLoS ONE, 2014
Eradication of smallpox and discontinuation of the vaccination campaign resulted in an increase in the percentage of unvaccinated individuals, highlighting the need for postexposure efficient countermeasures in case of accidental or deliberate viral ...
Tomer Israely, Sharon Melamed, Hagit Achdout, Noam Erez, Boaz Politi, Trevor Waner, Shlomo Lustig, Nir Paran   +7 more
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Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector

Zoonoses
Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.
Hao Sun, Xinwen Chen, Yun Wang
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