Results 121 to 130 of about 10,068 (192)

Splicing therapeutics in SMN2 and APOB [PDF]

, 2009
Splicing therapeutics are defined as the deliberate modification of RNA splicing to achieve therapeutic goals. Various techniques for splicing therapeutics have been described, and most of these involve the use of antisense oligonucleotide-based ...
Khoo, B., Krainer, A. R.
core  

Modulation of swimming in the gastropod Melibe leonina by nitric oxide [PDF]

, 2002
Nitric oxide (NO) is a gaseous intercellular messenger produced by the enzyme nitric oxide synthase. It has been implicated as a neuromodulator in several groups of animals, including gastropods, crustaceans and mammals.
Newcomb, James M., Watson, Winsor H., III   +1 more
core   +1 more source

Immaturity of the neuromuscular junction in spinal muscular atrophy mouse models. [PDF]

Front Cell Neurosci
Tabares L, Fuentes-Moliz A, Cano R, Ruiz R, Arumugam S.   +4 more
europepmc   +1 more source

RNA-binding proteins TDP-43 and FUS promote R-loop resolution and regulate transcription termination. [PDF]

J Biol Chem
Zhao DY, Nabeel-Shah S, Ni Z, Pu S, Zhong G, Schmitges FW, Braunschweig U, Blencowe BJ, Greenblatt JF.   +8 more
europepmc   +1 more source

RNA biomarkers in spinal muscular atrophy: enhancing pathogenesis understanding and guiding precision medicine. [PDF]

Cell Mol Life Sci
Alberti C, Berardinelli A, Comi GP, Ottoboni L, Corti S.   +4 more
europepmc   +1 more source

Fibro-adipogenic progenitor cells from murine SMA muscles are intrinsically adipogenic. [PDF]

Proc Natl Acad Sci U S A
Luo YE, Abe-Teh Z, Alsaghir T, Heiden KD, Basso KB, Barton ER.   +5 more
europepmc   +1 more source

Spliceosomal Sm core assembly: AlphaFold 3 predicted structure and phosphorylation-dependent regulation of the human 6S complex. [PDF]

Comput Struct Biotechnol J
Grimmler M, Reinhart M, Alers S, Peter C.   +3 more
europepmc   +1 more source

Novel Translational Concept: Axon-to-Muscle Exosomal Signaling as an Emerging Therapeutic Target in Spinal Muscular Atrophy. [PDF]

Biomedicines
Fajkić A, Belančić A, Lam YW, Rački V, Pilipović K, Janković T, Mežnarić S, Mršić-Pelčić J, Vitezić D.   +8 more
europepmc   +1 more source

Fast-Dissolving Sodium Alginate-Based Microneedle Patch Integrating Tranilast and Glabridin-Loaded Nanoparticles for Dual-Action Hypertrophic Scar Therapy. [PDF]

Biomater Res
Younas A, Sohail M, Li Y, Zhou Q, Shen Y, Wang S, Shi Y, Shang Z, Shao C, Xiao J.   +9 more
europepmc   +1 more source

SUMO2 promotes histone pre-mRNA processing by stabilizing histone locus body interactions and facilitating U7 snRNP assembly. [PDF]

Genes Dev
He S, Lyu P, Skinner MW, Desotell A, Foley B, McCaig CM, Wang W, Qian J, Tong L, Marzluff WF, Matunis MJ.   +10 more
europepmc   +1 more source