Results 121 to 130 of about 5,400 (185)

<i>Entamoeba histolytica</i> spliceosome structural components. [PDF]

Microbiology (Reading)
Canela-Pérez I, Saucedo-Cárdenas O, Avila-Bonilla RG, Galindo-Rosales JM, Valdés J.   +4 more
europepmc   +1 more source

SMN Deficiency in SMA: Splicing Gone Awry

, 2010
Spinal muscular atrophy (SMA) is the most common motor neuron degenerative disease and is the principal genetic cause of infant mortality, affecting 1 in every 6000 newborns.
Levin, Stephanne
core  

Immaturity of the neuromuscular junction in spinal muscular atrophy mouse models. [PDF]

Front Cell Neurosci
Tabares L, Fuentes-Moliz A, Cano R, Ruiz R, Arumugam S.   +4 more
europepmc   +1 more source

Haloperidol induces neuroprotection and enhances neuromuscular function in both murine and human models of spinal muscular atrophy. [PDF]

Exp Mol Med
Menduti G, Perez-Gomez R, Berenger-Currias N, Ruatti C, Espinosa-Espinosa J, Januel C, Konieczny P, Artero R, Martinat C, Boido M.   +9 more
europepmc   +1 more source

RNA-binding proteins TDP-43 and FUS promote R-loop resolution and regulate transcription termination. [PDF]

J Biol Chem
Zhao DY, Nabeel-Shah S, Ni Z, Pu S, Zhong G, Schmitges FW, Braunschweig U, Blencowe BJ, Greenblatt JF.   +8 more
europepmc   +1 more source

RNA biomarkers in spinal muscular atrophy: enhancing pathogenesis understanding and guiding precision medicine. [PDF]

Cell Mol Life Sci
Alberti C, Berardinelli A, Comi GP, Ottoboni L, Corti S.   +4 more
europepmc   +1 more source

Purification and functional characterization of the SMN-complex in Drosophila melanogaster

, 2008
Die Zusammenlageurng spleißosomaler UsnRNPs erfolgt beim Menschen und anderen Vertebraten durch den makromolekularen SMN-Komplex. Dieser besteht aus insgesamt neun Proteinen, genannt SMN und Gemin2-8.
Kroiß, Matthias
core  

Fibro-adipogenic progenitor cells from murine SMA muscles are intrinsically adipogenic. [PDF]

Proc Natl Acad Sci U S A
Luo YE, Abe-Teh Z, Alsaghir T, Heiden KD, Basso KB, Barton ER.   +5 more
europepmc   +1 more source

KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS. [PDF]

JCI Insight
Akiyama T, Zeng Y, Guo C, Gautier O, Koepke L, Lyons H, Molotsky E, Bombosch JS, Sianto O, Ross JP, Hoang P, Zhao L, Spencer C, Sumner CJ, Monje M, Day JW, Gitler AD.   +16 more
europepmc   +1 more source

Gene Targeted Therapies for Neurodegenerative Disorders: Strategies and Implications in ALS and SMA. [PDF]

Genes (Basel)
Yesbek Kaymaz A, Bora-Akoğlu G, Erdem Yurter H, Grunseich C.   +3 more
europepmc   +1 more source