Results 291 to 295 of about 43,875 (295)

Purmorphamine activates the Hedgehog pathway by targeting Smoothened

Nature Chemical Biology, 2005
Surajit Sinha, James K Chen
exaly  

Structural basis of Smoothened regulation by its extracellular domains

Nature, 2016
Eamon F X Byrne, Paul S Miller, George Hedger   +2 more
exaly  

Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells

Nature Cell Biology, 2018
Valentina Cigliola, Luiza M Ghila, Leon Van Gurp   +2 more
exaly  

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

ACS Medicinal Chemistry Letters, 2010
Xu Wu, Tove Tuntland
exaly  

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

Nature Cell Biology, 2003
exaly