Results 91 to 100 of about 112,374 (150)

snake venom

, 2005
In order to study the role of neutrophils in the acute local pathological alterations induced by Bothrops jararaca snake venom, and in the process of skeletal muscle regeneration that follows, an experimental model was developed in mice pretreated with ...
Cristina M. Fernandes, Zuliani, JP, Juliana P. Zuliani, Zuliani J.P., Irene Fernandes, Fernandes I., Zamunér, Stella Regina, Fernando Chaves, Teixeira C.F.P., Cruz-Hofling M.A., Chaves, F, Teixeira, CFP, Gutierrez, JM, Fernandes, CM, Fernandes, I, Teixeira, Catarina de Fátima, Zamuner S.R., Chaves F., Chaves Mora, Fernando, Fernandes, Irene, Cruz Höfling, Maria Alice, Zuliani, Juliana Pavan, José María Gutiérrez, Catarina F. P. Teixeira, Zamuner, SR, Fernandes, Cristina Maria, Stella R. Zamunér, Gutierrez J.M., María Alice Cruz‐Hofling, Gutiérrez, José María, Fernandes C.M., Cruz-Hofling, MA   +31 more
core   +1 more source

Protease Activity Profiling of Snake Venoms Using High-Throughput Peptide Screening

Toxins, 2019
Snake venom metalloproteinases (SVMPs) and snake venom serine proteinases (SVSPs) are among the most abundant enzymes in many snake venoms, particularly among viperids. These proteinases are responsible for some of the clinical manifestations classically
Konstantinos Kalogeropoulos, Andreas Frederik Treschow, Ulrich auf dem Keller, Teresa Escalante, Alexandra Rucavado, José María Gutiérrez, Andreas Hougaard Laustsen, Christopher T. Workman   +7 more
doaj   +1 more source

Therapeutic potential of snake venom: Toxin distribution and opportunities in deep learning for novel drug discovery

Medicine in Drug Discovery
Snake venom is a rich source of bioactive molecules that hold great promise for therapeutic applications. These molecules can be broadly classified into enzymes and non-enzymes, each showcasing unique medicinal properties.
Anas Bedraoui, Montamas Suntravat, Salim El Mejjad, Salwa Enezari, Naoual Oukkache, Elda E. Sanchez, Jacob A. Galan, Rachid El Fatimy, Tariq Daouda   +8 more
doaj   +1 more source

Inhibition of hemorragic snake venom components: old and new approaches.

, 2010
Snake venoms are complex toxin mixtures. Viperidae and Crotalidae venoms, which are hemotoxic, are responsible for most of the envenomations around the world.
RAVERA, SILVIA, CALZIA, DANIELA, PANFOLI, ISABELLA, MORELLI, ALESSANDRO   +3 more
core   +1 more source

Venomics of Trimeresurus (Popeia) nebularis, the Cameron Highlands Pit Viper from Malaysia: Insights into Venom Proteome, Toxicity and Neutralization of Antivenom

Toxins, 2019
Trimeresurus nebularis is a montane pit viper that causes bites and envenomation to various communities in the central highland region of Malaysia, in particular Cameron’s Highlands.
Choo Hock Tan, Kae Yi Tan, Tzu Shan Ng, Evan S.H. Quah, Ahmad Khaldun Ismail, Sumana Khomvilai, Visith Sitprija, Nget Hong Tan   +7 more
doaj   +1 more source

Suramin inhibits the early effects of PLA(2) neurotoxins at mouse neuromuscular junctions: a twitch tension study [PDF]

, 2011
Several phospholipase A(2) (PLA(2)) neurotoxins from snake venoms can affect acetylcholine release at the neuromuscular junction. In isolated nerve-muscle preparations three distinct phases have been described for this phenomenon: An initial transient ...
Fathi, Behrooz, Rowan, Edward G, Harvey, Alan L   +2 more
core  

Processing of pro-tumor necrosis factor-α by venom metalloproteinases: A hypothesis explaining local tissue damage following snake bite: A hypothesis explaining local tissue damage following snake bite

, 1996
Venom-induced necrosis is a common local debilitating sequela of bites by many vipers, frequently resulting in severe permanent scarring and deformity. Antivenoms are not effective under these circumstances unless administered within a few minutes of the
Politi, Vincenzo, Theakston, Robert David Geoffrey, Dennison, Jeremy Michael Thomas Jonathan, Paine, Mark; id_orcid, Crampton, Julian Moray, Moura-da-Silva, Ana Maria, Laing, Gavin David   +6 more
core   +1 more source

Clinical effectiveness of hymenoptera venom immunotherapy [PDF]

, 2013
Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Scheipl, Fabian, Darsow, Ulf, Reider, Norbert, Bonifazi, Floriano, Aberer, Werner, Schmid-Grendelmeier, Peter, Ruëff, Franziska, Treudler, Regina, Biló, Maria Beatrice, Sturm, Gunter Johannes, Küchenhoff, Helmut, Severino, Maurizio, Wüthrich, Brunello, Seitz, Michael J., Quercia, Oliviero, Bodzenta-Lukaszyk, Anna, Lang, Roland, Haeberli, Gabrielle, Campi, Paolo, Hawranek, Thomas, Müller, Ulrich, Przybilla, Bernhard   +21 more
core   +1 more source

Crotalid snake venom subproteomes unraveled by the antiophidic protein DM43

, 2009
Snake venoms are mixtures of proteins and peptides with different biological activities, many of which are very toxic. Several animals, including the opossum Didelphis aurita, are resistant to snake venoms due to the presence of neutralizing factors in ...
Valente, Richard H., Rocha, Surza L. G., Chapeaurouge, Alex, Trugilho, Monique R. O., Perales, Jonas, Domont, Gilberto B., Ferreira, Ana G. C. Neves, León, Ileana R.   +7 more
core   +1 more source

Toxicological analyses of the venoms of Nigerian vipers Echis ocellatus and Bitis arietans

Tropical Medicine and Health
Background Among the medically important snakes in Nigeria, Echis ocellatus and Bitis arietans have the most lethal venom. These venoms were classified according to the presence of snake venom metalloproteinases (SVMPs), snake venom phospholipase A2 ...
Emeka John Dingwoke, Fatima Adis Adamude, Aliyu Salihu, Mujitaba Suleiman Abubakar, Abdullahi Balarabe Sallau   +4 more
doaj   +1 more source