Results 21 to 30 of about 22,720 (280)

Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled Substrates

open access: yesBiology, 2023
Snakebite envenoming is an important public health issue with devastating consequences and annual mortality rates that range between 81,000 and 138,000.
Mátyás A. Bittenbinder   +8 more
doaj   +1 more source

Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins

open access: yesToxins, 2023
The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes and may cause cytotoxic ...
Eric Wachtel   +8 more
doaj   +1 more source

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]

open access: yes, 2015
Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J.   +3 more
core   +4 more sources

Qualitative Analysis of Proteins in Two Snake Venoms, Gloydius Blomhoffii and Agkistrodon Acutus. [PDF]

open access: yesJ Pharmacopuncture, 2022
Objectives: Snake venom is a complex mixture of various pharmacologically active substances, such as small proteins, peptides, and organic and mineral components.
Ha SJ   +6 more
europepmc   +2 more sources

Polyvalent Snake Antivenoms: Production Strategy and Their Therapeutic Benefits

open access: yesToxins, 2023
Snake envenomation remains an important yet neglected medical problem in many countries, with around five million people affected, and over a hundred thousand deaths annually. Plasma-derived antivenoms are the main therapeutic agent available. Monovalent
Kavi Ratanabanangkoon
doaj   +1 more source

Viperidae snake venom phospholipase A2 . Biochemical targets for the action of protein in the human blood circulatory system. Part 1 (review of literature)

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
Snake venoms have been fervently studied for decades for two reasons: 1) high death rate due to snake bites; 2) numerous components of snake venoms prove useful in medicine and treatment of diverse pathologies. Snake venom phospholipases A2 are among the
L. V. Galebskaya   +3 more
doaj   +1 more source

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

open access: yes, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B.   +12 more
core   +1 more source

Snake Venoms in Cancer Therapy: Past, Present and Future

open access: yesToxins, 2018
Cancer is one of the leading causes of morbidity and mortality worldwide, and the discovery of new drugs for cancer therapy is one of the most important objectives for the pharmaceutical industry.
Li Li, Jianzhong Huang, Yao Lin
doaj   +1 more source

Crotalus ruber [PDF]

open access: yes, 2006
Number of Pages: 17Integrative BiologyGeological ...
Beaman, Kent R., Dugan, Eric A.
core   +1 more source

Robotic modeling of snake traversing large, smooth obstacles reveals stability benefits of body compliance [PDF]

open access: yesRoyal Society Open Science (2020), 7, 191192, 2020
Snakes can move through almost any terrain. Although their locomotion on flat surfaces using planar gaits is inherently stable, when snakes deform their body out of plane to traverse complex terrain, maintaining stability becomes a challenge. On trees and desert dunes, snakes grip branches or brace against depressed sand for stability.
arxiv   +1 more source

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