Results 41 to 50 of about 15,264 (232)

Identification of presynaptic neurotoxin complexes in the venoms of three Australian copperheads (Austrelaps spp.) and the efficacy of tiger snake antivenom to prevent or reverse neurotoxicity [PDF]

, 2011
The venom of the Australian lowlands copperhead, Austrelaps superbus, produces significant and potentially lethal neurotoxic paralysis in cases of clinical envenomation. However, little is known about the neurotoxic components within this venom or venoms
Marcon, F, Nicholson, GM
core   +1 more source

Crotalus ruber [PDF]

, 2006
Number of Pages: 17Integrative BiologyGeological ...
Beaman, Kent R., Dugan, Eric A.
core   +1 more source

Snake Venom

, 2022
Venomous snakes belonging to the family Viperidae, Elapidae, Colubridae and Hydrophidae, produces snake venom in order to facilitate immobilization and digestion of prey, act as defense mechanism against threats. Venom contains zootoxins which is a highly modified saliva that is either injected via fangs during a bite or spitted.
Arokia, Rani, Asirwatham Pushpa, Serena, McConnell, Marie   +1 more
openaire   +3 more sources

Cytotoxicity and morphological analysis of cell death induced by Bothrops venoms from the northeast of Argentina

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
Bothrops snake venoms have been proved toxic to a variety of cell types, in both in vivo and in vitro models. Studies on the pharmacological actions of Bothrops venoms from Argentina are relatively scarce and the direct action of the crude venoms has not
S Bustillo, H Lucero, LC Leiva, O Acosta, EB Kier Joffé, JO Gorodner   +5 more
doaj   +1 more source

Snake Venom Gland Organoids [PDF]

Cell, 2020
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types. Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids that recapitulate essential features of the pertinent epithelium. Here, we establish long-term expanding venom gland organoids from several snake species.
Post, Yorick, Puschhof, Jens, Beumer, Joep, Kerkkamp, Harald M, de Bakker, Merijn A G, Slagboom, Julien, de Barbanson, Buys, Wevers, Nienke R, Spijkers, Xandor M, Olivier, Thomas, Kazandjian, Taline D, Ainsworth, Stuart, Iglesias, Carmen Lopez, van de Wetering, Willine J, Heinz, Maria C, van Ineveld, Ravian L, van Kleef, Regina G D M, Begthel, Harry, Korving, Jeroen, Bar-Ephraim, Yotam E, Getreuer, Walter, Rios, Anne C, Westerink, Remco H S, Snippert, Hugo J G, van Oudenaarden, Alexander, Peters, Peter J, Vonk, Freek J, Kool, Jeroen, Richardson, Michael K, Casewell, Nicholas R, Clevers, Hans   +30 more
openaire   +7 more sources

Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom [PDF]

, 2012
Snakebite envenomation is considered a highly relevant public health hazard in South America, having an impact in terms of mortality and morbidity.
Carvalho, Daniela Cajado, Juliano, Luiz, Juliano, Maria Aparecida, Kuniyoshi, Alexandre Kazuo, Portaro, Fernanda Calheta Vieira, Rocha, Marisa, Tambourgi, Denise Vilarinho   +6 more
core   +2 more sources

Evaluation of Antifungal Activity of Naja pallida and Naja mossambica Venoms against Three Candida Species

Toxins, 2020
In contrast to comprehensively investigated antibacterial activity of snake venoms, namely crude venoms and their selected components, little is known about antifungal properties of elapid snake venoms. In the present study, the proteome of two venoms of
Ewelina Kuna, Aleksandra Bocian, Konrad K. Hus, Vladimir Petrilla, Monika Petrillova, Jaroslav Legath, Anna Lewinska, Maciej Wnuk   +7 more
doaj   +1 more source

A Strategy for Efficient Preparation of Genus-Specific Diagnostic Antibodies for Snakebites

Frontiers in Immunology, 2021
As said by former United Nations Secretary-General Kofi Annan, “Snakebite is the most important tropical disease you’ve never heard of.” Listed as a priority neglected tropical disease by the World Health Organization, snakebite envenoming (SBE) kills in
Chengbo Long, Chengbo Long, Feilong Wu, Feilong Wu, Qiumin Lu, Qiumin Lu, Bing Xie, Chuanbin Shen, Jiayao Li, Yanling Deng, Ping Liang, Yongzhi Yu, Ren Lai, Ren Lai   +13 more
doaj   +1 more source

Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin

Angewandte Chemie International Edition, EarlyView.
We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu, Yo Matsumoto, Koichi Hagiwara, Masayuki Inoue   +3 more
wiley   +1 more source

High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches.

PLoS Neglected Tropical Diseases, 2020
Snakebite is a neglected tropical disease that results in a variety of systemic and local pathologies in envenomed victims and is responsible for around 138,000 deaths every year.
Julien Slagboom, Marija Mladić, Chunfang Xie, Taline D Kazandjian, Freek Vonk, Govert W Somsen, Nicholas R Casewell, Jeroen Kool   +7 more
doaj   +1 more source