Results 61 to 70 of about 7,174 (182)

Cross neutralization of Afro-Asian cobra and Asian krait venoms by a Thai polyvalent snake antivenom (Neuro Polyvalent Snake Antivenom). [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Snake envenomation is a serious public health threat in the rural areas of Asian and African countries. To date, the only proven treatment for snake envenomation is antivenom therapy.
Poh Kuan Leong, Si Mui Sim, Shin Yee Fung, Khomvilai Sumana, Visith Sitprija, Nget Hong Tan   +5 more
doaj   +1 more source

‘I, Me, Myself’: Selfhood and Melancholy in the Journals of Gertrude Savile (1697–1758)

Journal for Eighteenth-Century Studies, EarlyView.
Abstract This article examines the journals of Gertrude Savile from 1727 in light of recent scholarship on early modern and eighteenth‐century melancholy. The concept had myriad associations with medicine, physiology, the imagination, and feeling, but questions remain about how melancholy during this period was considered by those outside the narrow ...
Daniel Beaumont
wiley   +1 more source

Significant Far‐Right Challenges to Australian Society? The XYZ and AustraliaOne

Australian Journal of Politics &History, EarlyView.
ABSTRACT Scholars who analyse the Australian far‐right from a criminological or security studies perspective propose that activists and groups pose ‘political’ challenges to Australian society. This paper examines the far‐right news website The XYZ and the AustraliaOne political party, and argues that claims that the far‐right may normalise ...
Timothy Lynch
wiley   +1 more source

Colubrid Venom Composition: An -Omics Perspective

Toxins, 2016
Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes, which actually represent a relatively small proportion of extant species of advanced snakes ...
Inácio L. M. Junqueira-de-Azevedo, Pollyanna F. Campos, Ana T. C. Ching, Stephen P. Mackessy   +3 more
doaj   +1 more source

Water Beings and Capitalist Relations in India's Sundarbans Delta

American Anthropologist, EarlyView.
ABSTRACT This article explores entanglements between water cosmologies and capitalist transformation in the Sundarbans delta of West Bengal, India. It traces how “awakened” tidal creeks have been iteratively enclosed as private fisheries from the colonial period to the present, with particular focus on the expansion of commercial aquaculture over the ...
Calynn Dowler
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Factors underlying the natural resistance of animals against snake venoms

Memorias do Instituto Oswaldo Cruz, 1989
The existence of mammals and reptilia with a natural resistance to snake venoms is known since a long time. This fact has been subjected to the study by several research workers.
H. Moussatché, J. Perales
doaj   +1 more source

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells

British Journal of Pharmacology, EarlyView.
Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn, John Daniel Pediani, Madihah Hussain, Jiayue Ling, Elaine Brown, Igor Belka, Eduardo Torres, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie, Yuan Yan Sin   +11 more
wiley   +1 more source

Cytotoxicity of Southeast Asian snake venoms

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
Cytotoxicity of venoms from eleven medically important snakes found in Southeast Asia (Naja kaouthia, Naja siamensis, Naja sumatrana, Ophiophagus hannah, Bungarus candidus, Bungarus fasciatus, Enhydrina schistosa, Calloselasma rhodostoma, Trimeresurus ...
A Jamunaa, J Vejayan, I Halijah, SH Sharifah, S Ambu   +4 more
doaj   +1 more source

Retrieving Your Concepts: Iris Murdoch on Original Sin

European Journal of Philosophy, EarlyView.
Abstract In The Sovereignty of Good, Iris Murdoch argues that our moral thinking will be impoverished until it possesses a secular conception of original sin. Such a notion would need to remove unacceptable Christian baggage while retaining a genuine claim to be a descendant of the original Christian concept.
Samuel Filby
wiley   +1 more source