Results 51 to 60 of about 75,733 (225)

Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Envenomation of humans by snakes is a complex and continuously evolving medical emergency, and treatment is made that much more difficult by the diverse biochemical composition of many venoms.
Cassandra M Modahl, Stephen P Mackessy
doaj   +1 more source

Profiling the Murine Acute Phase and Inflammatory Responses to African Snake Venom: An Approach to Inform Acute Snakebite Pathology

open access: yesToxins, 2022
Snake envenoming causes rapid systemic and local effects that often result in fatal or long-term disability outcomes. It seems likely that acute phase and inflammatory responses contribute to these haemorrhagic, coagulopathic, neurotoxic, nephrotoxic and
Jaffer Alsolaiss   +4 more
doaj   +1 more source

Hybridization between Crotalus aquilus and Crotalus polystictus Species: A Comparison of Their Venom Toxicity and Enzymatic Activities

open access: yesBiology, 2022
Hybridization is defined as the interbreeding of individuals from two populations distinguishable by one or more heritable characteristics. Snake hybridization represents an interesting opportunity to analyze variability and how genetics affect the venom
Octavio Roldán-Padrón   +8 more
doaj   +1 more source

Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis

open access: yesToxins, 2014
Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar   +10 more
doaj   +1 more source

Cytotoxicity and morphological analysis of cell death induced by Bothrops venoms from the northeast of Argentina

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2009
Bothrops snake venoms have been proved toxic to a variety of cell types, in both in vivo and in vitro models. Studies on the pharmacological actions of Bothrops venoms from Argentina are relatively scarce and the direct action of the crude venoms has not
S Bustillo   +5 more
doaj   +1 more source

Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles

open access: yes, 2020
Latest advancement of omics technologies allows in-depth characterization of venom compositions. In the present work we present a proteomic study of two snake venoms of the genus Naja i.e., Naja naja (black cobra) and Naja oxiana (brown cobra) of ...
Zia Mughal   +8 more
core   +1 more source

Screening Snake Venoms for Toxicity to Tetrahymena Pyriformis Revealed Anti-Protozoan Activity of Cobra Cytotoxins

open access: yes, 2020
Snake venoms possess lethal activities against different organisms, ranging from bacteria to higher vertebrates. Several venoms were shown to be active against protozoa, however, data about the anti-protozoan activity of cobra and viper venoms are very ...
Vladislav Starkov   +9 more
core   +1 more source

Snake a-Neurotoxins and the Nicotinic Acetylcholine Receptor

open access: yes, 2016
α-Neurotoxins from snake venoms act on postsynaptic nicotinic acetylcholine receptors at the neuromuscular junction to produce clinically significant skeletal muscle paralysis following envenomation.
Nirthanan, Niru   +5 more
core   +1 more source

Protease activity profiling of snake venoms using high-throughput peptide screening [PDF]

open access: yes, 2019
Snake venom metalloproteinases (SVMPs) and snake venom serine proteinases (SVSPs) are among the most abundant enzymes in many snake venoms, particularly among viperids. These proteinases are responsible for some of the clinical manifestations classically
Andreas Treschow   +22 more
core   +1 more source

Morphophysiological dynamics of the proximal post‐testicular ducts in Crotalus durissus Linnaeus, 1758 (Squamata: Viperidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract The organization and function of reptilian excurrent ducts remain poorly characterized, particularly in Neotropical snakes. We provide the first integrative morphological, histochemical, immunohistochemical, and ultrastructural analysis of the proximal post‐testicular ducts of Crotalus durissus across reproductive stages.
Flávia Cappuccio de Resende   +9 more
wiley   +1 more source

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