Results 51 to 60 of about 78,509 (213)
Toxins, 2014 Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar +10 more
doaj +1 more source
, 2023 Snake venoms are primarily used to subjugate prey, and consequently, their evolution has been shown to be predominantly driven by diet-related selection pressure.
Kevin Arbuckle +3 more
core +1 more source
Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms [PDF]
, 2020 The phospholipase A2 (PLA2) inhibitor Varespladib (LY315920) and its orally bioavailable prodrug, methyl-Varespladib (LY333013) inhibit PLA2 activity of a wide variety of snake venoms.
Bruno Lomonte +7 more
core +1 more source
Protease activity profiling of snake venoms using high-throughput peptide screening [PDF]
, 2019 Snake venom metalloproteinases (SVMPs) and snake venom serine proteinases (SVSPs) are among the most abundant enzymes in many snake venoms, particularly among viperids. These proteinases are responsible for some of the clinical manifestations classically
Andreas Treschow +22 more
core +1 more source
Inhibition of Hemorragic Snake Venom Components: Old and New Approaches
, 2010 Snake venoms are complex toxin mixtures. Viperidae and Crotalidae venoms, which are hemotoxic, are responsible for most of the envenomations around the world.
Panfoli, Ravera, Calzia, Morelli
core +2 more sources
Journal of Venomous Animals and Toxins including Tropical Diseases, 2009 Bothrops snake venoms have been proved toxic to a variety of cell types, in both in vivo and in vitro models. Studies on the pharmacological actions of Bothrops venoms from Argentina are relatively scarce and the direct action of the crude venoms has not
S Bustillo +5 more
doaj +1 more source
The Target Selects the Toxin: Specific Amino Acids in Snake-Prey Nicotinic Acetylcholine Receptors That Are Selectively Bound by King Cobra Venoms [PDF]
, 2022 Snake venom is an adaptive ecological trait that has evolved primarily as a form of prey subjugation. Thus, the selection pressure for toxin diversification is exerted by the prey’s physiological targets, with this pressure being particularly acute for ...
Uthpala Chandrasekara +5 more
core +1 more source
Frontiers in Ecology and Evolution, 2019 Animal venoms have evolved over millions of years for prey capture and defense from predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides and proteins that induce harmful inflammatory and neurotoxic effects ...
Camila R. Ferraz +7 more
doaj +1 more source
, 2020 Snake venoms possess lethal activities against different organisms, ranging from bacteria to higher vertebrates. Several venoms were shown to be active against protozoa, however, data about the anti-protozoan activity of cobra and viper venoms are very ...
Vladislav Starkov +9 more
core +1 more source
Snake α-Neurotoxins and the Nicotinic Acetylcholine Receptor
, 2016 α-Neurotoxins from snake venoms act on postsynaptic nicotinic acetylcholine receptors at the neuromuscular junction to produce clinically significant skeletal muscle paralysis following envenomation.
Nirthanan, Niru +5 more
core +1 more source