Results 11 to 20 of about 15,264 (232)

Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving

open access: yesToxins, 2019
Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions.
Tarek Mohamed Abd El-Aziz   +2 more
doaj   +3 more sources

Snake Venoms in Cancer Therapy: Past, Present and Future

open access: yesToxins, 2018
Cancer is one of the leading causes of morbidity and mortality worldwide, and the discovery of new drugs for cancer therapy is one of the most important objectives for the pharmaceutical industry.
Li Li, Jianzhong Huang, Yao Lin
doaj   +3 more sources

Applications of snake venoms in treatment of cancer

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Snake venoms are folk medicines used since ages. The components of snake venoms have high specific affinity and actions on cells and cell components. Also snake venoms are largely cytotoxic to tumor cells than normal cells.
Vagish Kumar Laxman Shanbhag
doaj   +3 more sources

Multifunctional Toxins in Snake Venoms and Therapeutic Implications: From Pain to Hemorrhage and Necrosis

open access: yesFrontiers in Ecology and Evolution, 2019
Animal venoms have evolved over millions of years for prey capture and defense from predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides and proteins that induce harmful inflammatory and neurotoxic effects ...
Camila R. Ferraz   +7 more
doaj   +3 more sources

Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled Substrates

open access: yesBiology, 2023
Snakebite envenoming is an important public health issue with devastating consequences and annual mortality rates that range between 81,000 and 138,000.
Mátyás A. Bittenbinder   +8 more
doaj   +1 more source

Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins

open access: yesToxins, 2023
The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes and may cause cytotoxic ...
Eric Wachtel   +8 more
doaj   +1 more source

Snake venom ophthalmia [PDF]

open access: yesMedical Journal Armed Forces India, 2015
Snake venom ophthalmia is caused by venoms of spitting elapid and other snakes. The cobra is one of the most venomous snakes of genus Naja. There are more than 20 species of cobra like the King cobra of South Africa, Thailand, Burma, China, India, Malaysia, Philippines; the spitting cobra of Africa and parts of South East Asia; the Indian cobra found ...
Vijay Kumar, Sharma, V K, Baranwal
openaire   +2 more sources

Snake Venom Instability [PDF]

open access: yesZoologica Africana, 1978
Comparative electrophoretic studies were conducted on the venom of the rinkals (Hemachatus haemachatus). Egyptian cobra Naja haje haje) and puffadder (Bills arietans). Considerable differences in electrophoretic characteristics were found between fresh venom and commercial venom samples from the same species of snake.
Willemse, GT, Hattingh, J.
openaire   +2 more sources

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]

open access: yes, 2015
Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J.   +3 more
core   +9 more sources

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

open access: yes, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B.   +12 more
core   +1 more source

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