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Differential Effects of Marimastat and Prinomastat on the Metalloprotease Activity of Various Snake Venoms [PDF]
ToxinsSnakebite envenoming is a neglected tropical disease, responsible for approximately 140,000 deaths globally each year. Vipers and elapid snakes represent the most significant snake families in medical contexts, exhibiting a variety of venom components ...
Mahtab Khatibi +6 more
doaj +3 more sources
Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving
Toxins, 2019 Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions.
Tarek Mohamed Abd El-Aziz +1 more
exaly +4 more sources
Antiprotozoal Effect of Snake Venoms and Their Fractions: A Systematic Review [PDF]
Pathogens, 2021 Background: Protozoal infection is a lingering public health issue of great concern, despite efforts to produce drugs and vaccines against it. Recent breakthrough research has discovered alternative antiprotozoal agents encompassing the use of snake ...
Salihu Sabiu Musa +2 more
exaly +4 more sources
Two-Dimensional Blue Native/SDS Polyacrylamide Gel Electrophoresis for Analysis of Brazilian Bothrops Snake Venoms [PDF]
Toxins, 2022 Viperidae snakes are the most important agents of snakebites in Brazil. The protein composition of snake venoms has been frequently analyzed by means of electrophoretic techniques, but the interaction of proteins in venoms has barely been addressed.
Natacha Ferreira de Oliveira +2 more
doaj +3 more sources
Toxins, 2014 Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Rachid Eljaoudi, Jean-Marc Sabatier
exaly +4 more sources
Applications of snake venoms in treatment of cancer [PDF]
Asian Pacific Journal of Tropical Biomedicine, 2015 Snake venoms are folk medicines used since ages. The components of snake venoms have high specific affinity and actions on cells and cell components. Also snake venoms are largely cytotoxic to tumor cells than normal cells.
Vagish Kumar Laxman Shanbhag
exaly +4 more sources
Knowledge about Snake Venoms and Toxins from Colombia: A Systematic Review [PDF]
Toxins, 2023 Colombia encompasses three mountain ranges that divide the country into five natural regions: Andes, Pacific, Caribbean, Amazon, and Orinoquia. These regions offer an impressive range of climates, altitudes, and landscapes, which lead to a high snake ...
Jaime Andrés Pereañez +2 more
doaj +3 more sources
Children and Snakebite: Snake Venom Effects on Adult and Paediatric Plasma
Toxins, 2023 Snakebite is a globally neglected tropical disease, with coagulation disturbances being the primary pathology of many deadly snake venoms. Age-related differences in human plasma have been abundantly reported, yet the effect that these differences pose ...
Christina N. Zdenek +5 more
doaj +2 more sources
Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms. [PDF]
PLoS Neglected Tropical Diseases, 2023 Snakebite envenoming is a globally important public health issue that has devastating consequences on human health and well-being, with annual mortality rates between 81,000 and 138,000.
Matyas A Bittenbinder +8 more
doaj +2 more sources
Snake venoms and hemostasis [PDF]
Journal of Thrombosis and Haemostasis, 2005 Snake venoms are complex mixtures of biologically active proteins and peptides. Many of them affect hemostasis by activating or inhibiting coagulant factors or platelets, or by disrupting endothelium. Based on sequence, these snake venom components have been classified into various families, such as serine proteases, metalloproteinases, C-type lectins,
Lu, Q +2 more
openaire +5 more sources