Results 11 to 20 of about 10,248 (218)
Children and Snakebite: Snake Venom Effects on Adult and Paediatric Plasma
Toxins, 2023 Snakebite is a globally neglected tropical disease, with coagulation disturbances being the primary pathology of many deadly snake venoms. Age-related differences in human plasma have been abundantly reported, yet the effect that these differences pose ...
Christina N. Zdenek +5 more
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Snake venoms and hemostasis [PDF]
Journal of Thrombosis and Haemostasis, 2005 Snake venoms are complex mixtures of biologically active proteins and peptides. Many of them affect hemostasis by activating or inhibiting coagulant factors or platelets, or by disrupting endothelium. Based on sequence, these snake venom components have been classified into various families, such as serine proteases, metalloproteinases, C-type lectins,
Lu, Q +2 more
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Snake Venoms in Cancer Therapy: Past, Present and Future
Toxins, 2018 Cancer is one of the leading causes of morbidity and mortality worldwide, and the discovery of new drugs for cancer therapy is one of the most important objectives for the pharmaceutical industry.
Li Li, Jianzhong Huang, Yao Lin
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Snake Venom: A Promising Source of Neurotoxins Targeting Voltage-Gated Potassium Channels
Toxins, 2023 The venom derived from various sources of snakes represents a vast collection of predominantly protein-based toxins that exhibit a wide range of biological actions, including but not limited to inflammation, pain, cytotoxicity, cardiotoxicity, and ...
Altaf K. AlShammari +2 more
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Pharmacokinetics of Snake Venom [PDF]
Toxins, 2018 Understanding snake venom pharmacokinetics is essential for developing risk assessment strategies and determining the optimal dose and timing of antivenom required to bind all venom in snakebite patients. This review aims to explore the current knowledge of snake venom pharmacokinetics in animals and humans.
Suchaya Sanhajariya +2 more
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Toxins, 2020 Snake venoms contain components selected to immobilize prey. The venoms from Elapidae mainly contain neurotoxins, which are critical for rapid prey paralysis, while the venoms from Viperidae and Colubridae may contain fewer neurotoxins but are likely to ...
Huiwen Tian +9 more
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ToxinsActive compounds from natural sources, particularly snake venoms, are crucial for pharmaceutical development despite challenges in drug discovery. Snake venoms, historically used for medicinal purposes, contain bioactive peptides and enzymes that show ...
Diana Carolina Zona Rubio +2 more
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Qualitative Analysis of Proteins in Two Snake Venoms, Gloydius Blomhoffii and Agkistrodon Acutus [PDF]
Journal of Pharmacopuncture, 2022 Objectives: Snake venom is a complex mixture of various pharmacologically active substances, such as small proteins, peptides, and organic and mineral components.
Su-Jeong Ha +6 more
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Cytotoxicity of Southeast Asian snake venoms [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2012 Cytotoxicity of venoms from eleven medically important snakes found in Southeast Asia (Naja kaouthia, Naja siamensis, Naja sumatrana, Ophiophagus hannah, Bungarus candidus, Bungarus fasciatus, Enhydrina schistosa, Calloselasma rhodostoma, Trimeresurus ...
A Jamunaa +4 more
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Factors underlying the natural resistance of animals against snake venoms [PDF]
Memorias do Instituto Oswaldo Cruz, 1989 The existence of mammals and reptilia with a natural resistance to snake venoms is known since a long time. This fact has been subjected to the study by several research workers.
H. Moussatché, J. Perales
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