Results 1 to 10 of about 23,708 (288)

Snakebite envenoming. [PDF]

Nature Reviews Disease Primers, 2017
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J, Gutiérrez, José María, Habib, Abdulrazaq G, Harrison, Robert, Warrell, David A, Williams, David J   +5 more
core   +9 more sources

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Toxins, 2022
Snakebite is a neglected tropical disease that causes high rates of global mortality and morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by ...
Nessrin Alomran, Patricia Blundell, Jaffer Alsolaiss, Edouard Crittenden, Stuart Ainsworth, Charlotte A. Dawson, Rebecca J. Edge, Steven R. Hall, Robert A. Harrison, Mark C. Wilkinson, Stefanie K. Menzies, Nicholas R. Casewell   +11 more
doaj   +2 more sources

Snakebite in Indonesia

Acta Medica Indonesiana, 2016
Indonesia as one of the largest tropical and agricultural countries in the world shared the particularly high burden cases of snakebite. In the last decade, World Health Organization (WHO) has listed snakebite as one of the neglected tropical disease ...
Randy Adiwinata, Erni J Nelwan
doaj   +2 more sources

Association between footwear use and neglected tropical diseases: a systematic review and meta-analysis [PDF]

, 2014
BACKGROUND The control of neglected tropical diseases (NTDs) has primarily focused on preventive chemotherapy and case management. Less attention has been placed on the role of ensuring access to adequate water, sanitation, and hygiene and personal ...
A Alemu, A Liberati, A Martinez Cardenas, A Tremblay, AK Mukerji, B Yakob, BH Singer, BJ Marston, C Bird, CB Leal-Castellanos, CP Douglin, D Ayode, D Humphries, DM Sasaki, E Marion, E Price, EC Strunz, F Portaels, G Davey, G Davey, G Tadesse, Gail Davey, GC Ilechukwu, H Feldmeier, H Kloos, Hannah Clark, HG Lacerda, HO Ejere, I Ali, J Bartram, J Bethony, J Gutman, J Landier, J Lello, J Utzinger, J Utzinger, JC Nmor, Jeffrey Michael Bethony, JM Behnke, JO Alarcon, JZ Killewo, Jürg Utzinger, K Deribe, K Gunawardena, K Modjarrad, K Phiri, K Ziegelbauer, Kebede Deribe, Khizar Rafique, L Erosie, M Albonico, M Muehlen, M Nuti, M Thielecke, M Yunus Khan, MA Johnson, MC Freeman, ME Stocks, MI Gamboa, MR Sulong, N Njau, P Aimpun, P Bovet, P Hotez, P Phraisuwan, P Steinmann, PJ Hotez, PJ Hotez, PL Raghunathan, PM Emerson, PP Yori, PR Sanchez, PW Woodburn, R Anderson, R Kurup, RI Ejemot, RJ Traub, RL Pullan, S Knopp, S Mihrshahi, Sara Tomczyk, Simon J. Brooker, Stefanie Knopp, T Liabsuetrakul, US Ugbomoiko, V Chongsuvivatwong, V Jiraanankul, VJ Lee, WG Smillie, YB Molla, YB Molla   +90 more
core   +14 more sources

Developing and applying a training needs analysis tool for healthcare workers managing snakebite envenoming: A cross-sectional study in Eswatini. [PDF]

PLoS Neglected Tropical Diseases
A considerable number of patients present to hospitals in Eswatini each year following bites by venomous snakes. Effectively diagnosing and treating patients with snakebite envenoming requires healthcare workers to have a variety of generic and snakebite-
Jonathan Steinhorst, Clare Baker, Sara Padidar, Thea Litschka-Koen, Ezekiel Ngwenya, Lindelwa Mmema, Brent Thomas, Nondumiso Shongwe, Trevor Sithole, Mbongiseni Mathobela, Anna Trelfa, Nicholas R Casewell, David G Lalloo, Robert A Harrison, Jonathan Pons, Ymkje Stienstra   +15 more
doaj   +2 more sources

Namibian spitting cobra, Naja nigricincta nigricincta (Zebra snake): Antibiotic profile of bacteria cultured from the oral pharynx, venom and snakebite wounds

South African Medical Journal, 2023
This was a cross-sectional study with the aim of characterising Naja nigricincta nigricincta’s oral bacterial flora as well as accompanying sensitivities and resistance towards antibiotics.
E Saaiman, C Buys, F Theart
doaj   +1 more source

Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

Scientific Reports, 2022
Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor dose efficacy and potency.
Stefanie K. Menzies, Charlotte A. Dawson, Edouard Crittenden, Rebecca J. Edge, Steven R. Hall, Jaffer Alsolaiss, Mark C. Wilkinson, Nicholas R. Casewell, Robert A. Harrison, Stuart Ainsworth   +9 more
doaj   +1 more source

Fatal infective necrotising fasciitis: Complication following Naja nigricincta nigricincta bite (western barred spitting cobra/zebra snake)

South African Medical Journal, 2022
Wound infections following cytotoxic snakebites are common. Bites from Naja nigricincta nigricincta (an African spitting cobra) usually present as severe dermonecrosis spreading within the subdermal fascia layer.
EL Saaiman, PJ (Christo) Buys
doaj   +1 more source

Physiological constraints dictate toxin spatial heterogeneity in snake venom glands

BMC Biology, 2022
Background Venoms are ecological innovations that have evolved numerous times, on each occasion accompanied by the co-evolution of specialised morphological and behavioural characters for venom production and delivery.
Taline D. Kazandjian, Brett R. Hamilton, Samuel D. Robinson, Steven R. Hall, Keirah E. Bartlett, Paul Rowley, Mark C. Wilkinson, Nicholas R. Casewell, Eivind A. B. Undheim   +8 more
doaj   +1 more source

Commercial Antivenoms Exert Broad Paraspecific Immunological Binding and In Vitro Inhibition of Medically Important Bothrops Pit Viper Venoms

Toxins, 2022
Snakebite envenoming is a life threatening neglected tropical disease that represents a considerable public health concern in the tropics. Viperid snakes of the genus Bothrops are among those of greatest medical importance in Latin America, and they ...
Jaffer Alsolaiss, Nessrin Alomran, Laura Hawkins, Nicholas R. Casewell   +3 more
doaj   +1 more source