Results 11 to 20 of about 18,946 (244)

Local Ecological Knowledge and Cultural Perceptions of Snakes in Sudan. [PDF]

open access: yesEcol Evol
In Sudan, snakes are viewed through a mix of ecological, cultural, and spiritual lenses, shaping both conservation attitudes and health responses. Our survey (n = 192) across 16 states revealed frequent encounters, polarized conservation views, widespread killing of snakes, reliance on traditional remedies, and strong public support (95%) for ...
Baleela RMH   +3 more
europepmc   +2 more sources

Commercial Antivenoms Exert Broad Paraspecific Immunological Binding and In Vitro Inhibition of Medically Important Bothrops Pit Viper Venoms

open access: yesToxins, 2022
Snakebite envenoming is a life threatening neglected tropical disease that represents a considerable public health concern in the tropics. Viperid snakes of the genus Bothrops are among those of greatest medical importance in Latin America, and they ...
Jaffer Alsolaiss   +3 more
doaj   +1 more source

Profiling the Murine Acute Phase and Inflammatory Responses to African Snake Venom: An Approach to Inform Acute Snakebite Pathology

open access: yesToxins, 2022
Snake envenoming causes rapid systemic and local effects that often result in fatal or long-term disability outcomes. It seems likely that acute phase and inflammatory responses contribute to these haemorrhagic, coagulopathic, neurotoxic, nephrotoxic and
Jaffer Alsolaiss   +4 more
doaj   +1 more source

Snakebite envenoming [PDF]

open access: yesNature Reviews Disease Primers, 2017
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty. Snake venoms are complex mixtures of proteins that exert a wide range of toxic actions.
Gutiérrez, J   +5 more
openaire   +5 more sources

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

open access: yes, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B.   +12 more
core   +1 more source

Snakebite

open access: yesVidarbha Journal of Internal Medicine, 2022
Snakebite is a prevalent cause of morbidity and mortality in rural India. There is a great unawareness among the general public about this important occupational hazard and timely intervention like anti-snake venom. Furthermore, there is a confusion among primary health centre workers about the management due to various Western guidelines which are ...
Deepanshu Asudani, Archana Aher
openaire   +2 more sources

A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

open access: yesNature Communications, 2020
Snakebite is a life-threatening neglected tropical disease that is currently treated using different antibody-based antivenoms, each effective against bites of specific snake species, but not others. Here, the authors show that a combination of two toxin-
Laura-Oana Albulescu   +10 more
doaj   +1 more source

Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms

open access: yesNature Communications, 2023
Morbidity from snakebite envenoming affects approximately 400,000 people annually. Tissue damage at the bite-site often leaves victims with catastrophic life-long injuries and is largely untreatable by current antivenoms.
Steven R. Hall   +9 more
doaj   +1 more source

Early online

open access: yesSouth African Medical Journal, 2023
This article explores the management of snakebite to vulnerable patient groups, namely children and pregnant women as well as providing detail on the current best practice when caring for venom ophthalmia and surgical wounds resulting from snakebite ...
T Hardcastle   +6 more
doaj   +1 more source

Global mortality of snakebite envenoming between 1990 and 2019

open access: yesNature Communications, 2022
Snakebite envenoming is a leading cause of mortality among neglected tropical diseases. Here, the authors analyze a global data repository and estimate that snakebite envenoming caused over 63,000 deaths in 2019, primarily concentrated in South Asia and ...
GBD 2019 Snakebite Envenomation Collaborators
doaj   +1 more source

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