Results 11 to 20 of about 15,315 (196)

A Case Report of Postpartum Hemorrhage Secondary to Snake Bite Envenomation: A Pathogenesis and Current Management Review. [PDF]

Case Rep Obstet Gynecol
Background Snakebite envenomation (SBE) is a tropical disease with significant global morbidity and mortality, particularly affecting low‐resource settings. During pregnancy, SBE poses unique challenges, increasing both maternal and fetal mortality. Limited access to antivenom and delayed treatment further worsen outcomes.
Loza-Hernandez F, Haro A, Carrión G, Loza H.   +3 more
europepmc   +2 more sources

Local Ecological Knowledge and Cultural Perceptions of Snakes in Sudan. [PDF]

Ecol Evol
In Sudan, snakes are viewed through a mix of ecological, cultural, and spiritual lenses, shaping both conservation attitudes and health responses. Our survey (n = 192) across 16 states revealed frequent encounters, polarized conservation views, widespread killing of snakes, reliance on traditional remedies, and strong public support (95%) for ...
Baleela RMH, Elamin MEMO, Mohammad A, Saeed SAK.   +3 more
europepmc   +2 more sources

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B., Lakshminarayanan, Karthik, Layfield, Harry J., Mehmi, Amita, Patel, Ketan, Ravishankar, Divyashree, Salim, Anika, Sonavane, Medha, Trim, Steven A., Vaiyapuri, Rajendran, Vaiyapuri, Sakthivel, Vallance, Thomas M., Williams, Harry F.   +12 more
core   +1 more source

Snakebite

Vidarbha Journal of Internal Medicine, 2022
Snakebite is a prevalent cause of morbidity and mortality in rural India. There is a great unawareness among the general public about this important occupational hazard and timely intervention like anti-snake venom. Furthermore, there is a confusion among primary health centre workers about the management due to various Western guidelines which are ...
Deepanshu Asudani, Archana Aher
openaire   +2 more sources

A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

Nature Communications, 2020
Snakebite is a life-threatening neglected tropical disease that is currently treated using different antibody-based antivenoms, each effective against bites of specific snake species, but not others. Here, the authors show that a combination of two toxin-
Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth, Jaffer Alsolaiss, Edouard Crittenden, Charlotte A. Dawson, Rowan Softley, Keirah E. Bartlett, Robert A. Harrison, Jeroen Kool, Nicholas R. Casewell   +10 more
doaj   +1 more source

Association between footwear use and neglected tropical diseases: a systematic review and meta-analysis [PDF]

, 2014
BACKGROUND The control of neglected tropical diseases (NTDs) has primarily focused on preventive chemotherapy and case management. Less attention has been placed on the role of ensuring access to adequate water, sanitation, and hygiene and personal ...
A Alemu, A Liberati, A Martinez Cardenas, A Tremblay, AK Mukerji, B Yakob, BH Singer, BJ Marston, C Bird, CB Leal-Castellanos, CP Douglin, D Ayode, D Humphries, DM Sasaki, E Marion, E Price, EC Strunz, F Portaels, G Davey, G Davey, G Tadesse, Gail Davey, GC Ilechukwu, H Feldmeier, H Kloos, Hannah Clark, HG Lacerda, HO Ejere, I Ali, J Bartram, J Bethony, J Gutman, J Landier, J Lello, J Utzinger, J Utzinger, JC Nmor, Jeffrey Michael Bethony, JM Behnke, JO Alarcon, JZ Killewo, Jürg Utzinger, K Deribe, K Gunawardena, K Modjarrad, K Phiri, K Ziegelbauer, Kebede Deribe, Khizar Rafique, L Erosie, M Albonico, M Muehlen, M Nuti, M Thielecke, M Yunus Khan, MA Johnson, MC Freeman, ME Stocks, MI Gamboa, MR Sulong, N Njau, P Aimpun, P Bovet, P Hotez, P Phraisuwan, P Steinmann, PJ Hotez, PJ Hotez, PL Raghunathan, PM Emerson, PP Yori, PR Sanchez, PW Woodburn, R Anderson, R Kurup, RI Ejemot, RJ Traub, RL Pullan, S Knopp, S Mihrshahi, Sara Tomczyk, Simon J. Brooker, Stefanie Knopp, T Liabsuetrakul, US Ugbomoiko, V Chongsuvivatwong, V Jiraanankul, VJ Lee, WG Smillie, YB Molla, YB Molla   +90 more
core   +7 more sources

Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms

Nature Communications, 2023
Morbidity from snakebite envenoming affects approximately 400,000 people annually. Tissue damage at the bite-site often leaves victims with catastrophic life-long injuries and is largely untreatable by current antivenoms.
Steven R. Hall, Sean A. Rasmussen, Edouard Crittenden, Charlotte A. Dawson, Keirah E. Bartlett, Adam P. Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R. Casewell   +9 more
doaj   +1 more source

Early online

South African Medical Journal, 2023
This article explores the management of snakebite to vulnerable patient groups, namely children and pregnant women as well as providing detail on the current best practice when caring for venom ophthalmia and surgical wounds resulting from snakebite ...
T Hardcastle, A Engelbrecht, V Lalloo, C Bell, M Toubkin, F Motara, M Kajee   +6 more
doaj   +1 more source

Global mortality of snakebite envenoming between 1990 and 2019

Nature Communications, 2022
Snakebite envenoming is a leading cause of mortality among neglected tropical diseases. Here, the authors analyze a global data repository and estimate that snakebite envenoming caused over 63,000 deaths in 2019, primarily concentrated in South Asia and ...
GBD 2019 Snakebite Envenomation Collaborators
doaj   +1 more source

Mass Drug Administration and beyond: how can we strengthen health systems to deliver complex interventions to eliminate neglected tropical diseases? [PDF]

, 2015
Achieving the 2020 goals for Neglected Tropical Diseases (NTDs) requires scale-up of Mass Drug Administration (MDA) which will require long-term commitment of national and global financing partners, strengthening national capacity and, at the community ...
Adams, ER, Bockarie, MJ, Harrison, RA, Hollingsworth, T, Kelly-Hope, LA, Kovacic, V, Lehane, M, Macpherson, EE, Paine, MJI, Reimer, LJ, Torr, SJ   +10 more
core   +7 more sources