Results 71 to 80 of about 73,344 (342)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Involvement of complexin 2 in docking, locking and unlocking of different SNARE complexes during sperm capacitation and induced acrosomal exocytosis.

open access: yesPLoS ONE, 2012
Acrosomal exocytosis (AE) is an intracellular multipoint fusion reaction of the sperm plasma membrane (PM) with the outer acrosomal membrane (OAM). This unique exocytotic event enables the penetration of the sperm through the zona pellucida of the oocyte.
Pei-Shiue J Tsai   +3 more
doaj   +1 more source

The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. [PDF]

open access: yes, 2016
Cell polarity and precise subcellular protein localization are pivotal to neuronal function. The SNARE machinery underlies intracellular membrane fusion events, but its role in neuronal polarity and selective protein targeting remain unclear.
Albertolle, Mary E   +7 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

PASSIVE TORQUE SIMULATION OF SMALL ANGULAR CONTACT BEARING AT HIGH SPEED [PDF]

open access: yes, 2017
Description of common ball bearing torque models was presented and adopted to the complex thermo-mechanical model of the high speed spindle. Ball bearing passive torque was measured on the own high-speed spindle design.
Kekula J., Smolík J., Sulitka M.
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion

open access: yesNature Communications, 2017
Membrane fusion during exocytosis is mediated by interaction between SNARE proteins on vesicles and the cell membrane, but how SNARE complex assembly is initiated remains unknown.
Peng Yue   +7 more
doaj   +1 more source

The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly. [PDF]

open access: yesPLoS ONE, 2017
Vesicular transport of cellular cargo requires targeted membrane fusion and formation of a SNARE protein complex that draws the two apposing fusing membranes together. Insulin-regulated delivery and fusion of glucose transporter-4 storage vesicles at the
Asma Rehman   +10 more
doaj   +1 more source

Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release

open access: yesCell Reports, 2023
Summary: Neurotransmitter release requires assembly of the SNARE complex fusion machinery, with multiple SNARE-binding proteins regulating when and where synaptic vesicle fusion occurs.
Elizabeth A. Brija   +3 more
doaj   +1 more source

Clip and snare lifting technique to assist cannulation of a papilla hidden behind a mucosal fold [PDF]

open access: yes, 2015
No abstract ...
Arnelo, Urban   +6 more
core   +1 more source

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