Results 41 to 50 of about 1,856 (117)

Effect of SPRY4-IT1 depletion on apoptosis, and cell cycle arrest.

, 2018
(A) Apoptotic cell death was measured using Annexin V-FITC/PI method in pancreatic cancer cells after SPRY4-IT1-1 siRNA transfection for 48 hours. Control: control siRNA; siRNA-1: SPRY1-IT1 siRNA-1.
Heng Wei (138563), Wenhao Guo (2024272), Chunlai Nie (350669), Kunhong Zhong (4899052), Zhu Yuan (323633)   +4 more
core   +1 more source

Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator in vitro

, 2023
The pancreatic β cell synthesizes, packages, and secretes insulin in response to glucose-stimulation to maintain blood glucose homeostasis. Under diabetic conditions, a subset of β cells fail and lose expression of key transcription factors (TFs ...
Xu, Jerry, Ren, Hongxia, Sims, Emily K., Kanojia, Sukrati, Conley, Jason M., Spaeth, Jason M., Osmulski, Meredith, Davidson, Rebecca K.   +7 more
core   +1 more source

SND1 overexpression deregulates cholesterol homeostasis in hepatocellular carcinoma

, 2016
SND1 is a multifunctional protein participating, among others, in gene transcription and mRNA metabolism. SND1 is overexpressed in cancer cells and promotes viability and tumourigenicity of hepatocellular carcinoma cells.
Rueda Estévez, Yuri, Navarro Imaz, Hiart, Fresnedo Aranguren, María Olatz   +2 more
core   +1 more source

Molecular and cellular insights into the role of SND1 in lipid metabolism

, 2020
Staphylococcal nuclease and Tudor domain containing 1 (SND1) is an evolutionarily conserved protein present in eukaryotic cells from protozoa to mammals.
Rueda Estévez, Yuri, García Arcos, Itsaso, Martínez San Pelayo, María José, Navarro Imaz, Hiart, Ochoa Olascoaga, Begoña, Chico Carmona, Yolanda, Fresnedo Aranguren, María Olatz   +6 more
core   +1 more source

SND1-Targeted Gene Therapy for Hepatocellular Carcinoma [PDF]

, 2018
Staphylococcal nuclease and tudor-domain containing 1 (SND1) is an oncogene for a wide variety of cancers, including hepatocellular carcinoma (HCC). SND1 is a multifunctional protein regulating gene expression of proto-oncogenes and tumor suppressor ...
Mckiver, Bryan D
core   +1 more source

Characterization of Staphylococcal nuclease and tudor domain containing protein 1 (SND1) as a molecular target in Hepatocellular carcinoma and Non-alcoholic steatohepatitis [PDF]

, 2017
CHARACTERIZATION OF STAPHYLOCOCCAL NUCLEASE AND TUDOR DOMAIN CONTAINING PROTEIN 1 (SND1) AS A MOLECULAR TARGET IN HEPATOCELLULAR CARCINOMA AND NON-ALCOHOLIC STEATOHEPATITIS Nidhi Jariwala, PhD A dissertation submitted in partial fulfillment of the ...
Jariwala, Nidhi H
core   +1 more source

Figure S1 from Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma

, 2017
Generation and characterization of Alb/SND1 ...
Arun J. Sanyal (8605370), Devanand Sarkar (152580), Rachel G. Mendoza (14925857), Nidhi Jariwala (14925854), Chadia L. Robertson (14919417), Maaged A. Akiel (11454661), Paul B. Fisher (152591), Devaraja Rajasekaran (14919423), Xue-Ning Shen (8699220), Ayesha Siddiq (14919420), Mark A. Subler (14919429), Jolene J. Windle (7470833)   +11 more
core   +1 more source

Effect of SPRY4-IT1 on the cell apoptosis and invasion.

, 2018
(A) Apoptotic cell death was measured using Annexin V-FITC/PI method in cells after SPRY4-IT1 cDNA transfection plus Cdc20 shRNA infection for 48 hours. SP: SPRY4-IT1 plasmid; SP+DS: SPRY4-IT1 plus Cdc20 shRNA.
Heng Wei (138563), Wenhao Guo (2024272), Chunlai Nie (350669), Kunhong Zhong (4899052), Zhu Yuan (323633)   +4 more
core   +1 more source

The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi’s sarcoma-associated herpesvirus [PDF]

, 2019
N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and translation.
Wilson, S.A., Adrian Whitehouse, Whitehouse, A., Wilson, SA, Belinda Baquero-Perez, Wilson, Stuart A., Whitehouse, A, Baquero Pérez, Belinda, Antanaviciute, A., Whitehouse, Adrian, Ian M Carr, Yonchev, I.D., Stuart A Wilson, Agne Antanaviciute, Baquero-Perez, B., Antanaviciute, A, Carr, I.M., Yonchev, ID, Carr, Ian M., Carr, IM, Ivaylo D Yonchev, Yonchev, Ivaylo D., Baquero-Perez, B, Antanaviciute, Agne   +23 more
core   +1 more source

LncRna CPS1-IT1 Suppresses Cell Proliferation, Invasion and Metastasis in Colorectal Cancer [PDF]

, 2017
Background/Aims: Increasing evidence demonstrates that long non-coding RNAs (lncRNAs) regulate diverse cellular processes and cancer progression. Whether lncRNAs play any functional role in colorectal carcinoma (CRC) remains largely unknown.
Shijun Wang, Wei Zhang, Weitang Yuan, Xiaoming Gu, Junmin Song   +4 more
core   +1 more source