Results 91 to 100 of about 2,346 (167)

FORMULATION GEL SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) ALPHA-BISABOLOL AS ANTIOXIDANT

, 2022
Objective: Alpha-Bisabolol is monocyclic sesquiterpene alcohol obtained from the distillation of chamomile flowers (Matricaria chamomilla), that has many uses in the pharmaceutical industry, one of them is an antioxidant.
RAMADHAN, JANUAR AKBAR, NOOR, SITI UMRAH
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Solid self-nanoemulsifying cyclosporin A pellets prepared by fluid-bed coating: preparation, characterization and in vitro redispersibility

International Journal of Nanomedicine, 2011
Yang Lei1,2, Yi Lu2, Jianping Qi2, Sufang Nie1, Fuqiang Hu3, Weisan Pan1, Wei Wu21School of Pharmacy, Shenyang Pharmaceutical University, Shenyang; 2School of Pharmacy, Fudan University, Shanghai; 3School of Pharmacy, Zhejiang University, Hangzhou ...
Lei Y, Lu Y, Qi J, Nie S, Hu F, Pan W, Wu W   +6 more
doaj  

Enhancing oral bioavailability of escitalopram by self-nanoemulsifying drug delivery systems (SNEDDS): An in-vivo, in-vitro and in-silico study

Pakistan Journal of Pharmaceutical Sciences
This study aimed to develop SNEDDS to address the issue of low water solubility of escitalopram (ETP), which consequently leads to inadequate oral bioavailability. The formulation consisted of Tween 80, geranium oil, and polyethylene glycol 400.
Muhammad Junaid Asaad, Abdul Majeed, Syed Nisar Hussain Shah, Ghulam Abbas, Farhan Siddique, Muhammad Hanif, Furqan Muhammad Iqbal, Maryam Bashir   +7 more
doaj   +1 more source

Self nanoemulsifying drug delivery systems (SNEDDS)

, 2013
Bu çalışmanın amaçları, aseklofenak içeren kendiliğinden emülsiyon oluşturan formülasyon geliştirmek ve in vivo etkinliğini değerlendirmektir. Formülasyondaki en uygun yağ, YEM ve YYEM oranlarının belirlenmesi için üçgen faz diyagramları oluşturulmuştur.
Arslan, Şeyda Akkuş
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Solidification Techniques and Polymers Used in Converting Liquid Snedds to Solid Snedds: a Comprehensive Review

Enhancing the oral bioavailability of poorly water-soluble, lipophilic drug molecules remains a major challenge for pharmaceutical scientists, as modern drug discovery programs increasingly yield compounds with low aqueous solubility and high ...
KHAN, KASHAF, AIN, QURRATUL, AIN, SHABNAM, KUMAR, BABITA   +3 more
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Formulation and Characterization of Self Nanoemulsifying Drug Delivery System (SNEDDS) of Vitamin E

Background: Vitamin E is efficacious as an antioxidant that can fight free radicals, but has solubility in water and poor stability that causes low bioavailability.
Bakara, Yodhita Ruth Olivia
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Formulasi Self-Nanoemulsifying Drug Delivery System (SNEDDS) Asam Usnat untuk Aplikasi Topikal

Asam usnat merupakan metabolit sekunder lichen yang banyak ditemukan dalam genus Usnea sp, dengan berbagai aktivitas farmakologi. Namun, senyawa ini memiliki kelarutan yang rendah dalam air serta berpotensi hepatotoksik jika digunakan secara oral ...
Husna, Nurul
core   +1 more source

Optimasi Dan Uji Difusi Self Nano Emulsifying Drug Delivery System (Snedds) Alfa Tokoferol Asetat Sebagai Antioksidan [PDF]

, 2016
Alfa tokoferol adalah salah satu antioksidan untuk mencegah penuaan dini. Alfa tokoferol asetat bersifat tidak larut air, sehingga perlu di formulasi menjadi SNEDDS untuk meningkatkan penetrasi ke dalam dermis.
Chairissy, VashtiTalitha
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Leveraging 3D-printed microfluidic micromixers for the continuous manufacture of melatonin loaded SNEDDS with enhanced antioxidant activity and skin permeability

Vesicants are chemical warfare agents (CWAs) capable of causing severe skin damage and systemic toxicity. Melatonin, known for its anti-inflammatory and antioxidant properties, can mitigate the effects of these agents. Self-nano-emulsifying drug delivery
Tiboni, Mattia, Sanz Pérez, Amadeo, Romero Martínez, Manuel Alejandro, Serrano López, Dolores Remedios, González Burgos, Elena María, Ongoren, Baris, Aytug, Kara, Lalatsa, Aikaterini, Torrado Durán, Juan José, Casettari, Luca, Juberías, Antonio   +10 more
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A Critical Review of SNEDDS: Mechanistic Basis, Formulation Advances, and Future Directions in Oral Drug Delivery

: Although many newly developed therapeutic compounds exhibit low bioavailability due to poor aqueous solubility and limited gastrointestinal permeability, oral drug delivery remains the preferred route of administration because of ...
Sonali Dasharath Mali, Prachi Suresh Patil, Rabbika Rajjak Attar, Gauri Sachin Admuthe, Prajakta Kirankumar Kavathekar, Pravin Kondiba Pawar   +5 more
core   +1 more source