Administration of natural oil extracts suffers from low oral bioavailability and anti-proliferative activity. Self-nanoemulsifying drug delivery systems (SNEDDSs) are novel formulations to improvement of the efficacy of poorly water-soluble compounds. In
R. Nazari-Vanani +3 more
doaj +1 more source
SNEDDS AS LIPID-BASED NANOCARRIER SYSTEMS: CONCEPTS AND FORMULATION INSIGHTS [PDF]
Approximately 40 % of newly discovered chemical entities have low solubility and possess low bioavailability after oral administration. Lipid-based drug delivery systems (LBDDS) have recently become very popular because of their remarkable ability to ...
GOTTEMUKKULA, LAKSHMI DEVI +1 more
core +1 more source
Formulasi dan Aktivitas Antibakteri Gel Hand Sanitizer Ekstrak Air Daun Sirih Merah [PDF]
Latar Belakang: Tuntutan zaman mengharuskan manusia untuk menjaga kesehatannya agar terhindar dari penyakit. Salah satunya dengan menggunakan pembersih tangan. Hand sanitizer hadir sebagai solusi dari permasalahan tersebut.
Milala, Alasen Sembiring +2 more
core
Self Nanoemulsions for Oral Drug Delivery: A Comprehensive Review [PDF]
Nanotechnology is firmly acknowledged as significant methodology in drug conveyance that could impact the remedial exhibition of hydrophobic medications.
Kumar Pradeep, Prakash Satya
core +1 more source
Development of Irinotecan Dissolution Rate by Snedds
Maddela Chandra Shekhar, Pamu Sandhya
openaire +1 more source
Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
The present study aimed to develop orlistat-loaded solid self-nanoemulsifying drug delivery system preconcentrate (SSP) with the minimum use of lipid excipients for the enhanced solubility, in vitro dissolution, lipase inhibition, and in vivo performance.In the screening of solubilizing vehicles, Solutol HS15 and Lauroglycol 90 were selected as the ...
Dae Hun Kim +8 more
openaire +4 more sources
PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya Linn) DAN KUNYIT (Curcuma domestica) TERHADAP KECERNAAN, POPULASI PROTOZOA DAN PROTEIN MIKROBA PADA SAPI PERAH SECARA IN VITRO [PDF]
Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak daun pepaya (Carica papaya Linn) dan kunyit (Curcuma domestica) terhadap kecernaan bahan kering, bahan organik, populasi protozoa serta protein mikroba.
HARJANTI, Dian Wahyu +2 more
core
The use of nanoparticles in the formulation of essential oils [PDF]
زمینه و هدف: نانوتکنولوژی توانایی کنترل ویژگی های مواد در مقیاس اتمی و مولکولی است. حوزه پزشکی مدرن و داروسازی هم تحت تأثیر این فناوری قرار گرفته است. در این زمینه بیشترین تمرکز تحقیقاتی بر درون گیری ترکیبات فعال دارویی مخصوصاً داروهای سایتوتوکسیک بوده ...
Akhtari, Javad. +3 more
core
High throughput lipolysis-permeation in vitro model employing the mucus-PVPA barriers to assess drug absorption from lipid-based delivery systems [PDF]
In vitro lipolysis models are commonly used to assess the performance of lipid-based drug delivery systems (LbDDSs) in terms of their drug absorption potential; however, this in vitro approach has not always shown to correlate well with in vivo data ...
Brurok, Sunniva
core
Self-Nanoemulsifying Drug Delivery System (SNEDDS) of piroxicam [PDF]
Yudha Rizky Nuari +2 more
openaire +1 more source

