This research concentrated on developing and optimizing domperidone-loaded Self- nanoemulsifying drug delivery system (SNEDDS) to enhance solubility, stability, and availability. Domperidone (DOM), a lipophilic drug characterized by its limited solubility in water, was integrated into SNEDDS formulations utilizing a range of oils, surfactants, and ...
Sara Rassol, Adnan Burhan Qader
openaire +2 more sources
Yang Lei1,2, Yi Lu2, Jianping Qi2, Sufang Nie1, Fuqiang Hu3, Weisan Pan1, Wei Wu21School of Pharmacy, Shenyang Pharmaceutical University, Shenyang; 2School of Pharmacy, Fudan University, Shanghai; 3School of Pharmacy, Zhejiang University, Hangzhou ...
Lei Y +6 more
doaj
This study aimed to develop SNEDDS to address the issue of low water solubility of escitalopram (ETP), which consequently leads to inadequate oral bioavailability. The formulation consisted of Tween 80, geranium oil, and polyethylene glycol 400.
Muhammad Junaid Asaad +7 more
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A Review on Self Nanoemulsifying Drug Delivery System (SNEDDS)
Self-nanoemulsifying drug delivery systems (SNEDDS) have emerged as a promising approach for improving the oral bioavailability of poorly water-soluble drugs, particularly those classified under Biopharmaceutics Classification System (BCS) Class II and IV.
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Oral self-assembly nanoemulsion drives <i>in vivo</i> hepatic stellate cell-targeting drug delivery in liver fibrosis. [PDF]
Shen X +9 more
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<i>In Vivo</i> Bioimaging and Biodistribution of DiR-Labeled Solid SNEDDS of Black Sticky Rice Extract Using Neusilin® US2 as Solid Carrier. [PDF]
Kusumawati AH +3 more
europepmc +1 more source
Preparation, Oral SNEDDS Formulation, and In Vivo Evaluation of the HIV-1 Latency-Reversing Agent EK-16A. [PDF]
Jin L +20 more
europepmc +1 more source
Solid Pro-Nano Lipid Oral Formulations for Cannabidiol (CBD). [PDF]
Kumar A +5 more
europepmc +1 more source
A Novel Drug Delivery System for the Treatment of Lupus Nephritis: From Delivery System Design and Optimization to Treatment. [PDF]
Xiong X, Tao J, Jin Z, Hu Y.
europepmc +1 more source
Self-nanoemulsifying drug delivery system (SNEDDS) enhances the antidiabetic potential of <i>Averrhoa bilimbi</i> L. leaf extract: Integrated LC-MS/MS metabolomics, network pharmacology, and alpha-amylase inhibition. [PDF]
Aryani R +4 more
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