Results 81 to 90 of about 3,353 (212)

Validasi Metode Spektrofotometri UV-VIS untuk Studi Kelarutan Pentagamavunon-0 di dalam Pembawa Self-Nanoemulsifying Drug Delivery System [PDF]

, 2017
Pentagamavunon-0 memiliki aktivitas anti-inflamasi yang tinggi namun kelarutan dan absorpsinya kurang, yang dapat diperbaiki dengan formulasi SNEDDS. Salah satu parameter penting optimasi SNEDDS adalah kelarutan PGV-0 dalam berbagai minyak, surfaktan, co-
Astuti, I. Y. (Ika), Marchaban, M. (Marchaban), Martien, R. (Ronny), Nugroho, A. E. (Agung)   +3 more
core  

NANOTECHNOLOGY APPROACH-SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)

International Journal of Applied Pharmaceutics, 2023
This review article aims to develop nanotechnology in novel drug delivery systems using self-nano emulsifying drug delivery systems (SNEDDS). This Article was selected using a database with Prism Guideline diagrams. A total of 18 articles obtained from 2010-2020 were used as the primary reference to be analyzed using a systematic review method in the ...
Annisa, Rahmi, Mutiah, Roihatul, Yuwono, Mochammad, Hendradi, Esti   +3 more
openaire   +1 more source

Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

Particle &Particle Systems Characterization, Volume 42, Issue 1, January 2025.
SNEDDS improve bioavailability and solubility of poorly water‐soluble drugs, aiding in peptic ulcer treatment and regenerative healing. This innovative drug delivery bypasses side effects of conventional forms, utilizing biocompatible macromolecules to enhance solubility and promote healing. SNEDDS‐based systems show promise in boosting drug solubility
Syed Hassan Mujtaba, Rabia Arshad, Waqar Aman, Kashif Barkat, Abdul Malik, Anam Fatima, Salman Arshad Khan, Haleema Sadia, Gul e Maryam, Zeinab Moafian, Abbas Rahdar, M. Ali Aboudzadeh   +11 more
wiley   +1 more source

Formulation of Insulin Self Nanoemulsifying Drug Delivery System and Its In Vitro-In Vivo Study [PDF]

, 2018
Particulate delivery system can be used for improving the efficacy of protein and peptide drug. In addition to a polymer-based particulate delivery system, self-nanoemulsifying drug delivery system (SNEDDS), a lipid-based delivery system, is currently ...
Hakim, Lukman, Martien, Ronny, Suwaldi, Suwaldi, Winarti, Lina   +3 more
core   +2 more sources

In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B [PDF]

, 2020
Amphotericin B (AmpB), one of the most commonly used agents in the treatment of severe fungal infections and life-threatening parasitic diseases such as visceral Leishmaniasis, has a negligible oral bioavailability, primarily due to a low solubility and ...
Fatouros, Dimitrios G, Gika, Helen, Kontogiannidou, Eleni, Meikopoulos, Thomas, Müllertz, Anette, Panteris, Emmanuel, Vizirianakis, Ioannis S   +6 more
core   +1 more source

QbD‐Based Development of Self‐Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self‐nanoemulsifying drug delivery system (SNEDDS) for the codelivery of simvastatin and ezetimibe using a quality‐by‐design ...
Sani Ega Priani, Anis Yohana Chaerunisaa, Gofarana Wilar, Iyan Sopyan, Mozhgan Afshari   +4 more
wiley   +1 more source

Kaempferol-Phospholipid Complex: Formulation, and Evaluation of Improved Solubility, In Vivo Bioavailability, and Antioxidant Potential of Kaempferol [PDF]

, 2016
The current work describes the formulation and evaluation of a phospholipid complex of kaempferol toenhance the latter’s aqueous solubility, in vitro dissolution rate, in vivo antioxidant and hepatoprotectiveactivities, and oral bioavailability.
Anand, Sridhar, Dave, Vivek S, Patil, Arun T., Pethe, Anil M., Tatode, Amol A., Telange, Darshan R.   +5 more
core   +2 more sources

Multitarget Anti‐Candida Activity of Thai Plant Extracts and Essential Oils: Inhibiting Biofilm Formation, Denture Adhesion, and Germ Tube Formation

Scientifica, Volume 2025, Issue 1, 2025.
This study aimed to evaluate the efficacy of Thai plant extracts (PEs) and essential oils (EOs) against reference and clinical isolate strains of Candida albicans, focusing on their ability to inhibit biofilm formation, cell adhesion to denture acrylic, and germ tube formation. The minimum biofilm inhibition concentration (MBIC) and the minimum biofilm
Premnapa Sisopa, Supaporn Lamlertthon, Ruchadaporn Kaomongkolgit, Pratthana Chomchalao, Waree Tiyaboonchai, Simone Carradori   +5 more
wiley   +1 more source

Development and Evaluation of Simvastatin based Self nano emulsifying drug delivery system for treatment of Alzheimer’s Disease

Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.
Abstract Background Alzheimer’s disease (AD) is one of the leading causes of mortality and morbidity across the globe. Its incidences are increasing at an immense rate due to inadequate patient compliance. Hence there is a requirement for a requisite treatment strategy.
Hardeep  , Narendra Kumar Pandey
wiley   +1 more source

MELOXICAM SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM: FORMULATION AND RELEASE KINETICS ANALYSIS [PDF]

, 2021
Objective: This study aimed to find the best SNEDDS meloxicam formula and analyze the release kinetics of meloxicam SNEDDS and non-SNEDDS using DDSolver.  Methods: Meloxicam SNEDDS was prepared using sunflower seed oil, Cremophor RH 40 as a ...
AULIA, SALMA, WICAKSONO, YUDI, WINARTI, LINA   +2 more
core   +1 more source