Results 61 to 70 of about 1,285 (172)
Co-encapsulation of docetaxel and cyclosporin A into SNEDDS to promote oral cancer chemotherapy
Drug Delivery, 2019 Self-nanoemulsifying drug delivery system (SNEDDS) have been considered as a promising platform for oral delivery of many BCS (biopharmaceutics classification system) class IV drugs, such as docetaxel (DTX).
Weiping Cui +7 more
doaj +1 more source
Systematic development of optimized SNEDDS of artemether with improved biopharmaceutical and antimalarial potential [PDF]
Drug Delivery, 2016 The current studies entail systematic development of self-nanoemulsifying drug delivery systems (SNEDDS) containing medium-chain triglycerides (MCTs) and long-chain triglycerides (LCTs) for augmenting the biopharmaceutical performance of artemether. Equilibrium solubility and pseudoternary phase diagram studies facilitated selection of Captex 355 and ...
Chandra Bhushan, Tripathi +5 more
openaire +2 more sources
Advanced Therapeutics, Volume 8, Issue 11, November 2025.Green tea polyphenols, conjugated either covalently or non‐covalently to hemp protein, comprise an excellent stabilizing matrix for oxidatively‐sensitive small molecules. These nanoemulsions are highly stable to a variety of chemical and physical stressors, protecting the small molecule while allowing for easy uptake across cell membranes and rapid ...
William Charles Hosie +9 more
wiley +1 more source
Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review
Particle &Particle Systems Characterization, Volume 42, Issue 1, January 2025.SNEDDS improve bioavailability and solubility of poorly water‐soluble drugs, aiding in peptic ulcer treatment and regenerative healing. This innovative drug delivery bypasses side effects of conventional forms, utilizing biocompatible macromolecules to enhance solubility and promote healing. SNEDDS‐based systems show promise in boosting drug solubility
Syed Hassan Mujtaba +11 more
wiley +1 more source
Journal of Nanotechnology, Volume 2025, Issue 1, 2025.Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self‐nanoemulsifying drug delivery system (SNEDDS) for the codelivery of simvastatin and ezetimibe using a quality‐by‐design ...
Sani Ega Priani +4 more
wiley +1 more source
Scientifica, Volume 2025, Issue 1, 2025.This study aimed to evaluate the efficacy of Thai plant extracts (PEs) and essential oils (EOs) against reference and clinical isolate strains of Candida albicans, focusing on their ability to inhibit biofilm formation, cell adhesion to denture acrylic, and germ tube formation. The minimum biofilm inhibition concentration (MBIC) and the minimum biofilm
Premnapa Sisopa +5 more
wiley +1 more source
Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.Abstract Background Alzheimer’s disease (AD) is one of the leading causes of mortality and morbidity across the globe. Its incidences are increasing at an immense rate due to inadequate patient compliance. Hence there is a requirement for a requisite treatment strategy.
Hardeep , Narendra Kumar Pandey
wiley +1 more source
Alzheimer's &Dementia, Volume 20, Issue S4, December 2024.Abstract Background Alzheimer’s disease (AD) is a type of degenerative disorder that affects the brain. There are various herbal drugs that have been tested for their effectiveness in treating AD, and chrysin is one of them. Chrysin is a polyphenolic flavonoid that has several neuroprotective effects, including reducing the levels of AChE enzyme ...
Sukriti Vishwas +5 more
wiley +1 more source
Formulation and development of a self-nanoemulsifying drug delivery system of irbesartan
Journal of Advanced Pharmaceutical Technology & Research, 2011 Irbesartan (IRB) is an angiotensin II receptor blocker antihypertensive agent. The aim of the present investigation was to develop a self-nanoemulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of poorly water-soluble IRB.
Jaydeep Patel +3 more
doaj +1 more source
Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the impairment of cognitive development and disruption of neurocognitive function. This neuropathological condition is marked by neurodegeneration, loss of neural tissue, and the formation of neurofibrillary tangles and Aβ plaques. Various studies reported the
Bushra Bashir +4 more
wiley +1 more source