Results 41 to 50 of about 3,353 (212)

Biopharmaceutical classification of poorly soluble drugs with respect to “enabling formulations” [PDF]

, 2013
The large number of drug candidates with poor dissolution characteristics seen in the past decade, has fostered interest in so-called "enabling formulations", i.e., formulations which shall make such drugs bio-available.
Brandl, Martin, Buckley, Stephen, Frank, Kerstin, Fricker, Gert   +3 more
core   +1 more source

Methods to determine the interactions of micro- and nanoparticles with mucus [PDF]

, 2015
The present review provides an overview of methods and techniques for studying interactions of micro- and nanoparticulate drug delivery system with mucus.
Adebisi, Albrecht, Andreas Bernkop-Schnürch, Apgar, Barthelmes, Beatrice Cattoz, Bhat, Boegh, Bonner, Carlstedt, Chayed, Clausen, Cone, Corfield, Crater, Dawson, Dawson, de Campos, Dünnhaupt, Ensign, Fatin-Rouge, Florence, Florey, Friedl, Gargano, Georgiades, Georgiades, Griffiths, Groo, Groo, Gruber, Hutton, Irene Pereira de Sousa, Jeffrey Pearson, Jin, Julia Grießinger, Khanvilkar, Kirch, Laffleur, Lafitte, Lafitte, Lafitte, Lai, Lai, Lai, Lai, Lamprecht, Larhed, Li, Li, Li, Lieleg, Macierzanka, Macierzanka, Mark Gumbleton, Martin, Marx, Matthew Wilcox, Molino, Muthanna Abdulkarim, Müller, Müller, Nafee, Nordgard, Norris, Peter Griffiths, Ponchel, Primard, Rodahl, Rossi, Round, Salvador Borrós i Gómez, Sarah Dünnhaupt, Saxton, Schuster, Sejin Oh, Silva, Suh, Suh, Suk, Suk, Suk, Takeuchi, Takeuchi, Tirosh, Valentine, Veronese, Waigh, Wang, Wiecinski, Wiedmann, Yoncheva, Yuan   +92 more
core   +2 more sources

Enhancement of bioavailability of herbal drugs for treating viral therapy using SNEDDS as the delivery system [PDF]

BIO Web of Conferences
SNEDDS were developed with the objective of treating low bioavailability of drugs for antiviral drugs due to its low solubility. The scientist has increased their interest in improving bioavailability and absorption of poorly-water soluble drugs using ...
Rajput Rakesh, Kaur Simranjot, Ingole Yogiraj, Kumar Pandey Narendra, Wilson Kashish, Padhi Swarupanjali   +5 more
doaj   +1 more source

Developing health service delivery in a poor and marginalised community in North West Pakistan [PDF]

, 2018
Objective: To improve maternal health and reduce child mortality through developing health service delivery in a poor and marginalised community in North West Pakistan.
Bingley, Helen, Lowe, Nicola M, Medhi, Rashid, Ohly, Heather, Ul Haq, Zia, Zaman, Mukhtiar   +5 more
core   +1 more source

Brain Targeting Potential of Intravenous Carbamazepine SNEDDS

Journal of Molecular Pharmaceutics & Organic Process Research, 2017
Purpose: The objective of this study was to evaluate the ability of nano-droplets of Self Nano Emulsifying Drug Delivery System to diffuse into the brain tissue. Methods: The preconcentrate was prepared by dissolving oils, surfactants and cosolvents in 1:1 mixture of methanol and chloroform and flash evaporated at 50°C and was stored at room ...
Gannu Praveen Kumar, Rambhau D, Apte SS
openaire   +1 more source

Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro

Nanomaterials, 2019
Citral is an active compound naturally found in lemongrass, lemon, and lime. Although this pale-yellow liquid confers low water solubility, the compound has been reported to possess good therapeutic features including antiproliferative and anticancer ...
Mira Nadiah Mohd Izham, Yazmin Hussin, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah, Noorjahan Banu Alitheen   +8 more
doaj   +1 more source

Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer

Dose-Response, 2021
To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween
Mohamed F. Radwan, Mohamed A. El-Moselhy, Walied M. Alarif, Mohamed Orif, Nabil K. Alruwaili, Nabil A. Alhakamy   +5 more
doaj   +1 more source

Optimasi Formula Self-Nanoemulsifying Drug Delivery System (SNEDDS) Etil-p-metoksisinamat (EPMS)

Alchemy, 2022
Penelitian ini bertujuan untuk menentukan formula Self-Nanoemulsifying Drug Delivery System (SNEDDS) menggunakan zat aktif etil-p-metoksisinamat (EPMS).
Nur Amalia Choironi, Beti Pudyastuti, Giri Gumelar, Muhamad Salman Fareza, Triyadi Hendra Wijaya, Joko Setyono   +5 more
doaj   +1 more source

Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy [PDF]

, 2016
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase -- a key enzyme
Gisele Morais Branco, Kirsten H. Limesand, Micah G. Donovan, Randy Burd, Zoey Harris   +4 more
core   +3 more sources

From Liquid SNEDDS to Solid SNEDDS: A Comprehensive Review of Their Development and Pharmaceutical Applications

The AAPS Journal
Abstract The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field for their ability to enhance the solubility and absorption of hydrophobic drugs.
Sandrine Tanga, Poornima Ramburrun, Marique Aucamp   +2 more
openaire   +2 more sources