Results 21 to 30 of about 1,285 (172)

Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Oral Delivery of Cod Liver Oil

open access: yesBorneo Journal of Pharmacy, 2021
Cod liver oil (CLO) has long been used as medicine or as a functional food. The CLO is a potential source of vitamin D, vitamin A, and omega fatty acids (eicosapentaenoic acid/EPA and docosahexaenoic acid/DHA).
Sani Ega Priani   +2 more
doaj   +1 more source

Epigallocatechin‐3‐Gallate Encapsulated SNEDDS: A Novel Approach for Neuroprotection in Alzheimer’s Disease [PDF]

open access: yesAlzheimers Dement
Abstract Background Alzheimer's disease (AD) is a progressive neurodegenerative condition associated with cognitive decline and impaired neurocognitive function. It is characterized by neural degeneration, loss of brain tissue, accumulation of amyloid‐beta (Aβ) plaques and neurofibrillary tangles. Even though, several phytochemicals, including fisetin,
Pal B   +4 more
europepmc   +2 more sources

Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of Garcinia kola seeds ethanolic extract: formulation and in vivo antimalarial activity. [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2020
Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these seeds (GK) is reputed for oral antimalarial activity, some of its constituents have shown poor water ...
Grady K. Mukubwa   +5 more
doaj  

Antihyperglycemic activity of Centella asiatica (L.) Urb. leaf ethanol extract SNEDDS in zebrafish (Danio rerio)

open access: yesOpen Chemistry, 2021
This study aimed to identify the effectiveness of SNEDDS of Pegagan Leaf Ethanol Extract (PLE) to reduce fasting blood glucose (FBG) levels in zebrafish. Centella asiatica (L.) Urb.
Hayati Farida   +3 more
doaj   +1 more source

Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel

open access: yesAsian Journal of Pharmaceutical Sciences, 2019
Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel
Dawei Ding   +8 more
doaj   +1 more source

In vitro Naringenin SNEDDS Release Test by Dissolution

open access: yesNatural Sciences Engineering and Technology Journal, 2022
Naringenin is the main flavanone in grapefruit which has anti-inflammatory, anti-cancer, hepatoprotective and antilipid peroxidation effects. Its low solubility in water causes dissolution and low bioavailability when taken orally. This study aims to increase the solubility and bioavailability of naringenin by using the SNEDDS technique.
Gendis Purno Yudanti   +2 more
openaire   +1 more source

FORMULATION AND EVALUATION OF SOLID-SUPERSATURABLE-SNEDDS OF IBRUTINIB

open access: yesInternational Journal of Applied Pharmaceutics, 2022
Objective: The aim of current research is to develop a solid supersaturable self-nanoemulsifying drug delivery system (S-SNEDDS) of ibrutinib for enhancing the solubility and Bioavailability. Methods: Crossential O 94–Croduret 40SS–carbitol are chosen based on the maximum solubility of ibrutinib and were used to construct ternary phase diagrams with ...
K. NAVANEETHA, V. V. BASAVA RAO
openaire   +1 more source

The effect of surfactant on the solubility of kencur (Kaempferia galanga L.) rhizome ethanol extract in self nanoemulsifying drug delivery system [PDF]

open access: yesPharmaciana, 2022
Kencur (Kaempferia galanga L.) rhizome ethanol extract contains a lipophilic compound of ethyl p-methoxycinnamate. Self-nanoemulsifying drug delivery system (SNEDDS) formulation can increase the solubility of the extract in water.
Beti Pudyastuti, Triyadi Hendra Wijaya
doaj   +1 more source

Formulation self nano emulsifying drug delivery system glimepiride using oleic acid as oil phase [PDF]

open access: yesPharmaciana, 2017
Glimepiride is a third generation sulphonylurea antidiabetic drug. Glimepiride is poorly water soluble drug that may cause poor dissolution and unpredicted bioavailability.
Sani Ega Priani   +2 more
doaj   +1 more source

Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System

open access: yesMolecules, 2021
Luteolin (LUT) is a natural pharmaceutical compound that is weakly water soluble and has low bioavailability when taken orally. As a result, the goal of this research was to create self-nanoemulsifying drug delivery systems (SNEDDS) for LUT in an attempt
Faiyaz Shakeel   +8 more
doaj   +1 more source

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