Results 21 to 30 of about 3,353 (212)
Pharmaceutics, 2021 Background: The current study aimed to design a novel combination of lansoprazole (LNS) and curcumin (CUR) solid oral dosage form using bioactive self-nanoemulsifying drug delivery systems (Bio-SSNEDDS).
Abdulrahman Alshadidi +4 more
doaj +1 more source
Epigallocatechin‐3‐Gallate Encapsulated SNEDDS: A Novel Approach for Neuroprotection in Alzheimer’s Disease [PDF]
Alzheimers DementAbstract Background Alzheimer's disease (AD) is a progressive neurodegenerative condition associated with cognitive decline and impaired neurocognitive function. It is characterized by neural degeneration, loss of brain tissue, accumulation of amyloid‐beta (Aβ) plaques and neurofibrillary tangles. Even though, several phytochemicals, including fisetin,
Pal B +4 more
europepmc +2 more sources
Pharmaceutics, 2022 Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. Three
Mahmoud Teaima +5 more
doaj +1 more source
Development and optimization of Ropinirole loaded self-nanoemulsifying tablets
Future Journal of Pharmaceutical Sciences, 2023 Background The present research work aims to develop a Ropinirole-loaded self-Nanoemulsifying Drug Delivery system. Ropinirole has limited oral bioavailability due to substantial first-pass metabolism, which ultimately results in poor oral ...
Krunal Detholia +4 more
doaj +1 more source
Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Oral Delivery of Cod Liver Oil
Borneo Journal of Pharmacy, 2021 Cod liver oil (CLO) has long been used as medicine or as a functional food. The CLO is a potential source of vitamin D, vitamin A, and omega fatty acids (eicosapentaenoic acid/EPA and docosahexaenoic acid/DHA).
Sani Ega Priani +2 more
doaj +1 more source
Open Chemistry, 2021 This study aimed to identify the effectiveness of SNEDDS of Pegagan Leaf Ethanol Extract (PLE) to reduce fasting blood glucose (FBG) levels in zebrafish. Centella asiatica (L.) Urb.
Hayati Farida +3 more
doaj +1 more source
Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of Garcinia kola seeds ethanolic extract: formulation and in vivo antimalarial activity. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2020 Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these seeds (GK) is reputed for oral antimalarial activity, some of its constituents have shown poor water ...
Grady K. Mukubwa +5 more
doaj
In vitro Naringenin SNEDDS Release Test by Dissolution
Natural Sciences Engineering and Technology Journal, 2022 Naringenin is the main flavanone in grapefruit which has anti-inflammatory, anti-cancer, hepatoprotective and antilipid peroxidation effects. Its low solubility in water causes dissolution and low bioavailability when taken orally. This study aims to increase the solubility and bioavailability of naringenin by using the SNEDDS technique.
Gendis Purno Yudanti +2 more
openaire +1 more source
Formulasi dan Uji Karakteristik SNEDDS Asiklovir
Majalah Farmasetika, 2021 Asiklovir termasuk ke dalam biopharmaceuticals classification system (BCS) kelas III. Obat yang tergolong ke dalam BCS kelas III memiliki kelarutan tinggi dan permeabilitas rendah. SNEDDS terbukti dapat meningkatkan kelarutan, disolusi dan permeabilitas obat.
Nanda Dwi Akbar +2 more
openaire +2 more sources
Asian Journal of Pharmaceutical Sciences, 2019 Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel
Dawei Ding +8 more
doaj +1 more source