Results 21 to 30 of about 2,346 (167)

Review Artikel : Desain dan Karakteristik Self Nano Emulsifying Drug Delivery System (SNEDDS) [PDF]

, 2023
Objective: Sistem Nanoemulsi Penghantaran Obat (Self-Nanoemulsifying Drug Delivery System/SNEDDS) merupakan salah satu pendekatan inovatif dalam penghantaran obat yang bertujuan meningkatkan kelarutan dan bioavailabilitas obat-obatan yang sulit larut ...
Wiputri, Oktaviany Irma, Wahyuningsih, Etik, Samlan, Karima, Dessidianti, Rachma, Sari, Annisa Kartika, Isnaeni, Hanistya, Ria   +6 more
core   +1 more source

Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of Garcinia kola seeds ethanolic extract: formulation and in vivo antimalarial activity. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2020
Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these seeds (GK) is reputed for oral antimalarial activity, some of its constituents have shown poor water ...
Grady K. Mukubwa, Christian I. Nkanga, Aristote B. Buya, Jérémie K. Mbinze, Rui W.M. Krause, Patrick B. Memvanga   +5 more
doaj  

Antihyperglycemic activity of Centella asiatica (L.) Urb. leaf ethanol extract SNEDDS in zebrafish (Danio rerio)

Open Chemistry, 2021
This study aimed to identify the effectiveness of SNEDDS of Pegagan Leaf Ethanol Extract (PLE) to reduce fasting blood glucose (FBG) levels in zebrafish. Centella asiatica (L.) Urb.
Hayati Farida, Chabib Lutfi, Sekarraras Faiza Dea, Faizah Wan Syarifah   +3 more
doaj   +1 more source

Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel

Asian Journal of Pharmaceutical Sciences, 2019
Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel
Dawei Ding, Bingjun Sun, Weiping Cui, Qin Chen, Xuanbo Zhang, Haotian Zhang, Zhonggui He, Jin Sun, Cong Luo   +8 more
doaj   +1 more source

Epigallocatechin‐3‐Gallate Encapsulated SNEDDS: A Novel Approach for Neuroprotection in Alzheimer’s Disease [PDF]

Alzheimers Dement
Abstract Background Alzheimer's disease (AD) is a progressive neurodegenerative condition associated with cognitive decline and impaired neurocognitive function. It is characterized by neural degeneration, loss of brain tissue, accumulation of amyloid‐beta (Aβ) plaques and neurofibrillary tangles. Even though, several phytochemicals, including fisetin,
Pal B, Singh S, Bashir B, Vishwas S, Panda S.   +4 more
europepmc   +2 more sources

Self-Nanoemulsifying Drug Delivery System (SNEDDS) Using Lipophilic Extract of Viscum album subsp. austriacum (Wiesb.) Vollm. [PDF]

BACKGROUND AND PURPOSE Natural products are potential sources of anticancer components. Among various species, the lipophilic extract of the Viscum album subsp. austriacum (Wiesb.) Vollm. (VALE) has shown promising therapeutic potential.
Paes de Almeida, Valter, Rocha, Mariana Souza, Manfron, Jane, Holandino, Carla, Melo, Michelle Nonato de Oliveira, Baumgartner, Stephan, Carvalho, Aline Gabrielle Alves, de Campos, Vania Emerich Bucco, Pereira, Camila Faria de Amorim, Oliveira, Adriana Passos, Pereira, Ivania Paiva, Batista, João Vitor da Costa, Monchak, Irailson Thierry, Ricci-Júnior, Eduardo, Garrett, Rafael   +14 more
core   +4 more sources

Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

Acta Pharmaceutica Sinica B, 2019
This study assessed the influence of the composition of drug-free SNEDDS co-dosed with aqueous suspensions of carvedilol (CAR), cinnarizine (CIN) or R3040 on drug solubilization in a two-compartment in vitro lipolysis model.
ScheylaDaniela Siqueira Jørgensen, Thomas Rades, Huiling Mu, Kirsten Graeser, Anette Müllertz   +4 more
doaj   +1 more source

Formulation and Evaluation of Isorhamnetin SNEDDS for Neuroprotection in Alzheimer's Disease [PDF]

Alzheimers Dement
Abstract Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes. The disease is marked by the accumulation of amyloid‐beta plaques and tau tangles, which disrupt neuronal function and lead to cell death.
Panda S, Singh S, Bashir B, Pal B, Vishwas S, Kaur J.   +5 more
europepmc   +2 more sources

Solid Self-Nano Emulsifying Nanoplatform Loaded with Tamoxifen and Resveratrol for Treatment of Breast Cancer

Pharmaceutics, 2022
The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in SNEDDS with resveratrol (RES), which is a potent chemotherapeutic ...
Nupur Shrivastava, Ankit Parikh, Rikeshwer Prasad Dewangan, Largee Biswas, Anita Kamra Verma, Saurabh Mittal, Javed Ali, Sanjay Garg, Sanjula Baboota   +8 more
doaj   +1 more source

Formulation self nano emulsifying drug delivery system glimepiride using oleic acid as oil phase [PDF]

Pharmaciana, 2017
Glimepiride is a third generation sulphonylurea antidiabetic drug. Glimepiride is poorly water soluble drug that may cause poor dissolution and unpredicted bioavailability.
Sani Ega Priani, Nurrayyan, Fitrianti Darusman   +2 more
doaj   +1 more source