Results 31 to 40 of about 2,346 (167)

The effect of surfactant on the solubility of kencur (Kaempferia galanga L.) rhizome ethanol extract in self nanoemulsifying drug delivery system [PDF]

Pharmaciana, 2022
Kencur (Kaempferia galanga L.) rhizome ethanol extract contains a lipophilic compound of ethyl p-methoxycinnamate. Self-nanoemulsifying drug delivery system (SNEDDS) formulation can increase the solubility of the extract in water.
Beti Pudyastuti, Triyadi Hendra Wijaya
doaj   +1 more source

Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System

Molecules, 2021
Luteolin (LUT) is a natural pharmaceutical compound that is weakly water soluble and has low bioavailability when taken orally. As a result, the goal of this research was to create self-nanoemulsifying drug delivery systems (SNEDDS) for LUT in an attempt
Faiyaz Shakeel, Moad M. Alamer, Prawez Alam, Abdullah Alshetaili, Nazrul Haq, Fars K. Alanazi, Sultan Alshehri, Mohammed M. Ghoneim, Ibrahim A. Alsarra   +8 more
doaj   +1 more source

Antibacterial Activity of Self-Nanoemulsifying Drug Delivery System (SNEDDSS) Loaded with Mangosteen (Garcinia mangostana L.,) Peels against Baccilus subtitis, Bacillus cereus, and Staphylococcus aureus isolated from Diabetic Foot Ulcer Patients

Majalah Obat Tradisional, 2021
Diabetic Foot Ulcer is a complication of diabetes mellitus characterized by open sores on the surface of the skin or mucous membranes as well as extensive dead tissue followed by bacterial invasion. Patients with Diabetic Foot Ulcer are resistant to some
Liza Pratiwi
doaj   +1 more source

Physical and Chemical Stability Test of SNEDDS (Self-nanoemulsifying Drug Delivery System) and Nanoemulsion Ethyl Acetate Fraction of Garcinia mangostana L.

Majalah Obat Tradisional, 2018
The mangosteen peels (Garcinia mangostana L.) has high free radical scavengers activity. This study aims to determine the physical and chemical conditions that are formulated in SNEDDS and nanoemulsion preparations.
Liza Pratiwi, Achmad Fudholi, Ronny Martien, Suwidjiyo Pramono   +3 more
doaj   +1 more source

FORMULATION AND EVALUATION OF SOLID-SUPERSATURABLE-SNEDDS OF IBRUTINIB [PDF]

, 2022
Objective: The aim of current research is to develop a solid supersaturable self-nanoemulsifying drug delivery system (S-SNEDDS) of ibrutinib for enhancing the solubility and Bioavailability.
RAO, V. V. BASAVA, NAVANEETHA, K.
core   +1 more source

Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro

Nanomaterials, 2019
Citral is an active compound naturally found in lemongrass, lemon, and lime. Although this pale-yellow liquid confers low water solubility, the compound has been reported to possess good therapeutic features including antiproliferative and anticancer ...
Mira Nadiah Mohd Izham, Yazmin Hussin, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah, Noorjahan Banu Alitheen   +8 more
doaj   +1 more source

AKTIVITAS HIPOGLIKEMIK SNEDDS EKSTRAK ETANOL BUAH HARENDONG (Melastoma affine D.Don) PADA IKAN ZEBRA (Danio rerio) YANG DIINDUKSI ALOKSAN [PDF]

, 2022
Diabetes melitus merupakan penyakit kronik dengan prevalensi yang tinggi di Indonesia dan diperkirakan akan terus mengalami peningkatan. Buah Harendong (Melastoma affine D.Don) mempunyai kandungan senyawa flavonoid berupa antosianin dan fenol yang ...
Novitalia, Arnetta, Miladiyah, Isnatin
core   +1 more source

Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

Saudi Pharmaceutical Journal, 2015
A solid self-nanoemulsifying drug-delivery system (solid SNEDDS) has been explored to improve the solubility and dissolution profile of glipizide. SNEDDS preconcentrate was systematically optimized using a circumscribed central composite design by ...
Rajendra Narayan Dash, Habibuddin Mohammed, Touseef Humaira, Devi Ramesh   +3 more
doaj   +1 more source

Effectiveness of SNEDDS to Increased Oral Bioavailability in Antihypertension Agents: A Review [PDF]

, 2023
Hypertension is a disease that is well known, but the drug solubility of oral Antihypertension drugs has problems with their solubility. The aim of this study was to determine the effect of the SNEDDS formulation on oral Antihypertension drugs.
Wahyuningsih, Iis, Yulianto, Asep Nurrahman, Widyaningsih, Wahyu   +2 more
core   +1 more source

Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer

Dose-Response, 2021
To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween
Mohamed F. Radwan, Mohamed A. El-Moselhy, Walied M. Alarif, Mohamed Orif, Nabil K. Alruwaili, Nabil A. Alhakamy   +5 more
doaj   +1 more source