Results 31 to 40 of about 1,285 (172)

Solid Self-Nano Emulsifying Nanoplatform Loaded with Tamoxifen and Resveratrol for Treatment of Breast Cancer

Pharmaceutics, 2022
The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in SNEDDS with resveratrol (RES), which is a potent chemotherapeutic ...
Nupur Shrivastava, Ankit Parikh, Rikeshwer Prasad Dewangan, Largee Biswas, Anita Kamra Verma, Saurabh Mittal, Javed Ali, Sanjay Garg, Sanjula Baboota   +8 more
doaj   +1 more source

Physical and Chemical Stability Test of SNEDDS (Self-nanoemulsifying Drug Delivery System) and Nanoemulsion Ethyl Acetate Fraction of Garcinia mangostana L.

Majalah Obat Tradisional, 2018
The mangosteen peels (Garcinia mangostana L.) has high free radical scavengers activity. This study aims to determine the physical and chemical conditions that are formulated in SNEDDS and nanoemulsion preparations.
Liza Pratiwi, Achmad Fudholi, Ronny Martien, Suwidjiyo Pramono   +3 more
doaj   +1 more source

Antibacterial Activity of Self-Nanoemulsifying Drug Delivery System (SNEDDSS) Loaded with Mangosteen (Garcinia mangostana L.,) Peels against Baccilus subtitis, Bacillus cereus, and Staphylococcus aureus isolated from Diabetic Foot Ulcer Patients

Majalah Obat Tradisional, 2021
Diabetic Foot Ulcer is a complication of diabetes mellitus characterized by open sores on the surface of the skin or mucous membranes as well as extensive dead tissue followed by bacterial invasion. Patients with Diabetic Foot Ulcer are resistant to some
Liza Pratiwi
doaj   +1 more source

Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro

Nanomaterials, 2019
Citral is an active compound naturally found in lemongrass, lemon, and lime. Although this pale-yellow liquid confers low water solubility, the compound has been reported to possess good therapeutic features including antiproliferative and anticancer ...
Mira Nadiah Mohd Izham, Yazmin Hussin, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah, Noorjahan Banu Alitheen   +8 more
doaj   +1 more source

Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

Saudi Pharmaceutical Journal, 2015
A solid self-nanoemulsifying drug-delivery system (solid SNEDDS) has been explored to improve the solubility and dissolution profile of glipizide. SNEDDS preconcentrate was systematically optimized using a circumscribed central composite design by ...
Rajendra Narayan Dash, Habibuddin Mohammed, Touseef Humaira, Devi Ramesh   +3 more
doaj   +1 more source

Brain Targeting Potential of Intravenous Carbamazepine SNEDDS

Journal of Molecular Pharmaceutics & Organic Process Research, 2017
Purpose: The objective of this study was to evaluate the ability of nano-droplets of Self Nano Emulsifying Drug Delivery System to diffuse into the brain tissue. Methods: The preconcentrate was prepared by dissolving oils, surfactants and cosolvents in 1:1 mixture of methanol and chloroform and flash evaporated at 50°C and was stored at room ...
Gannu Praveen Kumar, Rambhau D, Apte SS
openaire   +1 more source

From Liquid SNEDDS to Solid SNEDDS: A Comprehensive Review of Their Development and Pharmaceutical Applications

The AAPS Journal
Abstract The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field for their ability to enhance the solubility and absorption of hydrophobic drugs.
Sandrine Tanga, Poornima Ramburrun, Marique Aucamp   +2 more
openaire   +2 more sources

Enhancement of bioavailability of herbal drugs for treating viral therapy using SNEDDS as the delivery system [PDF]

BIO Web of Conferences
SNEDDS were developed with the objective of treating low bioavailability of drugs for antiviral drugs due to its low solubility. The scientist has increased their interest in improving bioavailability and absorption of poorly-water soluble drugs using ...
Rajput Rakesh, Kaur Simranjot, Ingole Yogiraj, Kumar Pandey Narendra, Wilson Kashish, Padhi Swarupanjali   +5 more
doaj   +1 more source

Understanding the effect of lipid formulation loading and ethanol as a diluent on solidification of pitavastatin super-saturable SNEDDS using factorial design approach

Research in Pharmaceutical Sciences, 2019
Solidification of a preconcentrate lipid formulation namely self-nano emulsifying drug delivery system (SNEDDS) is required to achieve feasibility, flexibility, and a new concept of “dry nano-emulsion”.
Ilham Kuncahyo, Syaiful Choiri, Achmad Fudholi, Abdul Rohman, Ronny Martien   +4 more
doaj   +1 more source

Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer

Dose-Response, 2021
To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween
Mohamed F. Radwan, Mohamed A. El-Moselhy, Walied M. Alarif, Mohamed Orif, Nabil K. Alruwaili, Nabil A. Alhakamy   +5 more
doaj   +1 more source