Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids
Abstract Medical cannabis has received significant interest in recent years due to its promising benefits in the management of pain, anxiety, depression and neurological and movement disorders. Specifically, the major phytocannabinoids derived from the cannabis plant such as (−) trans‐Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD), have been shown
T. Srinivasa Reddy +2 more
wiley +1 more source
FORMULATION AND EVALUATION OF SOLID-SUPERSATURABLE-SNEDDS OF IBRUTINIB
Objective: The aim of current research is to develop a solid supersaturable self-nanoemulsifying drug delivery system (S-SNEDDS) of ibrutinib for enhancing the solubility and Bioavailability. Methods: Crossential O 94–Croduret 40SS–carbitol are chosen based on the maximum solubility of ibrutinib and were used to construct ternary phase diagrams with ...
K. NAVANEETHA, V. V. BASAVA RAO
openaire +1 more source
Formulation self nano emulsifying drug delivery system glimepiride using oleic acid as oil phase [PDF]
Glimepiride is a third generation sulphonylurea antidiabetic drug. Glimepiride is poorly water soluble drug that may cause poor dissolution and unpredicted bioavailability.
Sani Ega Priani +2 more
doaj +1 more source
Validated spectrofluorometric method for determination of gemfibrozil in self nanoemulsifying drug delivery systems (SNEDDS) [PDF]
A spectrofluorometric method has been developed and validated for the determination of gemfibrozil. The method is based on the excitation and emission capacities of gemfibrozil with excitation and emission wavelengths of 276 and 304 nm respectively. This
Aróztegui Trenchs, Montserrat +4 more
core +2 more sources
The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in SNEDDS with resveratrol (RES), which is a potent chemotherapeutic ...
Nupur Shrivastava +8 more
doaj +1 more source
Diabetic Foot Ulcer is a complication of diabetes mellitus characterized by open sores on the surface of the skin or mucous membranes as well as extensive dead tissue followed by bacterial invasion. Patients with Diabetic Foot Ulcer are resistant to some
Liza Pratiwi
doaj +1 more source
The effect of surfactant on the solubility of kencur (Kaempferia galanga L.) rhizome ethanol extract in self nanoemulsifying drug delivery system [PDF]
Kencur (Kaempferia galanga L.) rhizome ethanol extract contains a lipophilic compound of ethyl p-methoxycinnamate. Self-nanoemulsifying drug delivery system (SNEDDS) formulation can increase the solubility of the extract in water.
Beti Pudyastuti, Triyadi Hendra Wijaya
doaj +1 more source
UJI KARAKTERISTIK FISIKO KIMIA DAN STABILITAS MINYAK BIJI JINTAN HITAM DAN JAHE GAJAH DALAM SEDIAAN SNEDDS [PDF]
Background: Herbal plants are plants with active substances that can intervene in physiological and pathological functions to prevent or cure disease.
PURWANTO, AMARA FEBRIYANTI PUTRI
core
Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System
Luteolin (LUT) is a natural pharmaceutical compound that is weakly water soluble and has low bioavailability when taken orally. As a result, the goal of this research was to create self-nanoemulsifying drug delivery systems (SNEDDS) for LUT in an attempt
Faiyaz Shakeel +8 more
doaj +1 more source
The mangosteen peels (Garcinia mangostana L.) has high free radical scavengers activity. This study aims to determine the physical and chemical conditions that are formulated in SNEDDS and nanoemulsion preparations.
Liza Pratiwi +3 more
doaj +1 more source

