Development of Alectinib-Suspended SNEDDS for Enhanced Solubility and Dissolution
Pharmaceutics, 2022 Alectinib hydrochloride (ALH), a tyrosine kinase inhibitor, is a practically water-insoluble drug classified as BCS class IV. The present study aimed to develop novel suspended self-nanoemulsifying drug delivery system (Su-SNEDDS) to enhance the ...
Eun Ji Park +5 more
doaj +2 more sources
Nanomaterials, 2021 Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor solubility and permeability, thus leading to the development of intracellular pathogens induced multi-drug resistance and biofilms formation.
Rabia Arshad +7 more
doaj +2 more sources
Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Oral Delivery of Cod Liver Oil
Borneo Journal of Pharmacy, 2021 Cod liver oil (CLO) has long been used as medicine or as a functional food. The CLO is a potential source of vitamin D, vitamin A, and omega fatty acids (eicosapentaenoic acid/EPA and docosahexaenoic acid/DHA).
Sani Ega Priani +2 more
doaj +2 more sources
Enhancement of bioavailability of herbal drugs for treating viral therapy using SNEDDS as the delivery system [PDF]
BIO Web of ConferencesSNEDDS were developed with the objective of treating low bioavailability of drugs for antiviral drugs due to its low solubility. The scientist has increased their interest in improving bioavailability and absorption of poorly-water soluble drugs using ...
Rajput Rakesh +5 more
doaj +3 more sources
Optimasi Formula Self-Nanoemulsifying Drug Delivery System (SNEDDS) Etil-p-metoksisinamat (EPMS) [PDF]
Alchemy, 2022 Penelitian ini bertujuan untuk menentukan formula Self-Nanoemulsifying Drug Delivery System (SNEDDS) menggunakan zat aktif etil-p-metoksisinamat (EPMS).
Nur Amalia Choironi +5 more
doaj +2 more sources
Characterization of SNEDDS Formulated with Single Bulb Garlic and its Anti-Inflammatory Effect on 3T3-L1 [PDF]
Hayati Journal of BiosciencesInflammation is an early symptom of a disease that reduces the level of health. Single-bulb garlic (Allium sativum L.) is used medicinally as a plant with a broad pharmacological effect, especially anti-inflammatory activity.
Sri Rahayu Lestari +8 more
doaj +2 more sources
NANOTECHNOLOGY APPROACH-SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) [PDF]
, 2023 This review article aims to develop nanotechnology in novel drug delivery systems using self-nano emulsifying drug delivery systems (SNEDDS). This Article was selected using a database with Prism Guideline diagrams.
MUTIAH, ROIHATUL +3 more
core +3 more sources
Self-nanoemulsifying drug delivery systems (SNEDDS) for solubility enhancement - new approaches for determining appropriate formulations for liquid SNEDDS and their conversion to solid SNEDDS [PDF]
, 2022 The poor aqueous solubility of many drug substances has been addressed using different solubility enhancement approaches in the pharmaceutical technology field over the last decades.
Schmied, Fabian-Pascal (Dr.)
core +1 more source
Profil Ketoksikan Akut SNEDDS Propolis [PDF]
, 2022 Propolis memiliki efek imunostimulan yang tinggi namun tidak larut air dan memiliki bioavailabilitas yang rendah. Formulasi propolis dalam bentuk SNEDDS terbukti mampu meningkatkan aktivitas imunostimulannya, namun juga memberikan potensi ketoksikan ...
Hakim, Sherina Nabila Putri +3 more
core +4 more sources
Development and Evaluation of Paclitaxel‐Loaded Self‐Nanoemulsifying Drug Delivery System for Enhanced Cancer Therapy: A Promising Alternative to Cremophor EL–Based Formulation [PDF]
IET NanobiotechnolBackground and Purpose Paclitaxel’s clinical use is limited by poor aqueous solubility and Cremophor EL–related toxicity in commercial formulations. This study aimed to develop a self‐nanoemulsifying drug delivery system (SNEDDS) to improve paclitaxel solubility, bioavailability, and anticancer efficacy.
Almehmady A +6 more
europepmc +2 more sources