Results 51 to 60 of about 1,285 (172)

Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation

Pharmaceutics, 2016
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution rate.
Ali Nasr, Ahmed Gardouh, Mamdouh Ghorab
doaj   +1 more source

Potent Anticancer, Antimicrobial, and Anti‐Inflammatory Activities of Boswellia sacra Extracted Oil Nanoemulgel

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Boswellia sacra (B. sacra), the chemical name for frankincense essential oil, is utilized extensively to treat multiple kinds of cancers as well as skin disorders like acne, infections, and inflammations. The goal of this project is to develop a nanoemulgel using B.
Ahmad M. Eid, Hani Naseef, Murad Abualhasan, Dana Yassin, Sally Jaber, Adan Abu Gazaleh, Poorani Gurumallesh Prabu   +6 more
wiley   +1 more source

The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

Pharmaceutics, 2023
Reformulating poorly water-soluble drugs as supersaturated lipid-based formulations achieves higher drug loading and potentially improves solubilisation and bioavailability.
Amalie Møller, Hayley B. Schultz, Tahlia R. Meola, Paul Joyce, Anette Müllertz, Clive A. Prestidge   +5 more
doaj   +1 more source

Pilot Scale Extraction and Standardization of Begonia medicinalis Herbs as Raw Material for Anticancer Herbal Medicine

International Journal of Food Science, Volume 2026, Issue 1, 2026.
Begonia medicinalis is an endemic plant in Central Sulawesi that is traditionally used as an herbal medicine to treat cancer. This study is aimed at performing pilot‐scale extraction of B. medicinalis herbs followed by standardization of the obtained extract, including determination of phytochemical components and anticancer activity.
Muhammad Sulaiman Zubair, Nurul Putri Ramadhani Ayunanda, Evi Sulastri, Armini Syamsidi, Yandi Syukri, Adadi Parise   +5 more
wiley   +1 more source

Self-nanoemulsifying ramipril tablets: a novel delivery system for the enhancement of drug dissolution and stability

International Journal of Nanomedicine, 2019
Khalid F Alhasani,1 Mohsin Kazi,1,2 Mohamed Abbas Ibrahim,1 Ahmad A Shahba,1,2 Fars K Alanazi1,21Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia; 2Kayyali Chair for Pharmaceutical ...
Alhasani KF, Kazi M, Ibrahim MA, Shahba AA, Alanazi FK   +4 more
doaj  

Optimization of a Beverage Using Mixture Design With Operational Variables

Journal of Engineering, Volume 2026, Issue 1, 2026.
The optimization of formulated products often requires simultaneous consideration of mixture composition and processing conditions, as both factors can strongly influence the final response. In this study, a mixture experimental design incorporating process variables was applied to the optimization of a prepared beverage (margarita), with the objective
Javier Cruz-Salgado, Sergio Alonso-Romero, Misaela Francisco Márquez, Uziel Mejía González, Himadri Majumder   +4 more
wiley   +1 more source

Assessment of Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Ethyl Acetate Fraction from Mangosteen (Garcinia mangostana L.,) Peels to Eschericia coli, Pseudomonas aeroginosa, and Proteus mirabilis

Majalah Obat Tradisional, 2019
Mangosteen peels have antibacterial activity. SNEDDS has many advantages in developing a drug delivery system to increase the penetration of active compounds. The purpose of this study was to compare the effectiveness of the antibacterial SNEDDS of ethyl
Liza Pratiwi
doaj   +1 more source

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Nanomaterials, 2021
Hypertension is a cardiovascular disease that needs long-term medication. Oral delivery is the most common route for the administration of drugs. The present research is to develop piperine self-nanoemulsifying drug delivery system (PE-SNEDDS) using ...
Ameeduzzafar Zafar, Syed Sarim Imam, Nabil K. Alruwaili, Omar Awad Alsaidan, Mohammed H. Elkomy, Mohammed M. Ghoneim, Sultan Alshehri, Ahmed Mahmoud Abdelhaleem Ali, Khalid Saad Alharbi, Mohd Yasir, Kaveripakkam M. Noorulla, Sami I. Alzarea, Abdullah S. Alanazi   +12 more
doaj   +1 more source

Self‐Nanoemulsifying Drug Delivery System (SNEDDS) of Ethyl Acetate Fraction of Begonia medicinalis Herb and Ethanol Fraction of Moringa oleifera L. Leaves

Journal of Nanotechnology, Volume 2026, Issue 1, 2026.
The combination of ethyl acetate fraction of Begonia medicinalis and ethanol fraction of Moringa oleifera was developed into self‐nanoemulsifying drug delivery system (SNEDDS) to increase the solubility of combined fraction. This study aims to determine the optimal concentrations of virgin coconut oil (VCO), Tween 80, and propylene glycol using the D ...
Muhammad Sulaiman Zubair, Rahma Mutiani, Evi Sulastri, Armini Syamsidi, Saipul Maulana, Arwansyah Arwansyah, Arnab Biswas   +6 more
wiley   +1 more source

Combined Ramipril and Black Seed Oil Dosage Forms Using Bioactive Self-Nanoemulsifying Drug Delivery Systems (BIO-SNEDDSs)

Pharmaceuticals, 2022
Purpose: Ramipril (RMP)—an angiotensin-converting enzyme (ACE) inhibitor—and thymoquinone (THQ) suffer from poor oral bioavailability. Developing a combined liquid SNEDDS that comprises RMP and black seed oil (as a natural source of THQ) could lead to ...
Ahmad Abdul-Wahhab Shahba, Abdelrahman Y. Sherif, Ehab M. Elzayat, Mohsin Kazi   +3 more
doaj   +1 more source