Results 51 to 60 of about 3,353 (212)

Development and Evaluation of a Solid Self-Nanoemulsifying Drug Delivery System for Loratadin by Extrusion-Spheronization [PDF]

Advanced Pharmaceutical Bulletin, 2014
Purpose: Recently the liquid nanoemulsifying drug delivery systems (SNEDDS) have shown dramatic effects on improving oral bioavailability of poorly soluble drugs.
Mohammadreza Abbaspour, Negar Jalayer, Behzad Sharif Makhmalzadeh   +2 more
doaj   +1 more source

Enhancing biopharmaceutical performance of an anticancer drug by long chain PUFA based self-nanoemulsifying lipidic nanomicellar system. [PDF]

, 2017
The aim of this study was to develop polyunsaturated fatty acid (PUFA) long chain glyceride (LCG) enriched self-nanoemulsifying lipidic nanomicelles systems (SNELS) for augmenting lymphatic uptake and enhancing oral bioavailability of docetaxel and ...
Beg, Sarwar, Burrow, Andrea Julie, Katare, O P, Kaur Khurana, Rajneet, Kaur, Satvinder, Kesherwani, Prashant, Singh, Bhupinder, Singh, Kamalinder, Vashishta, Rakesh K   +8 more
core   +1 more source

FORMULASI, KARAKTERISASI DAN EVALUASI SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) EKSTRAK ETANOL KULIT BUAH NANAS SEBAGAI ANTIBAKTERI STREPTOCOCCUS MUTANS [PDF]

, 2021
Kulit buah nanas mengandung bromelain, flavonoid, tannin, dan saponin yang dapat dimanfaatkan sebagai antibakteri. Perkembangan teknologi formulasi diperlukan untuk meningkatkan aktivitas antibakteri.
., Suratmi, Indratmoko, Septiana, Issusilaningtyas, Elisa   +2 more
core   +1 more source

Role of Alternative Lipid Excipients in the Design of Self-Nanoemulsifying Formulations for Fenofibrate: Characterization, in vitro Dispersion, Digestion and ex vivo Gut Permeation Studies

Frontiers in Pharmacology, 2018
Background: The choice of lipid excipients and their origin are crucial determinant factors in the design of self-nanoemulsifying drug delivery system (SNEDDS).Aim: To investigate the aspects of alternative excipients which can influence the development ...
Aws Alshamsan, Aws Alshamsan, Mohsin Kazi, Mohamed M. Badran, Fars Kaed Alanazi   +4 more
doaj   +1 more source

DESIGN AND CHARACTERIZATION OF NANOSPRAY WITH SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM USING SINERGISTIC COMBINATION OF MELASTOMA MALABATHRICUM L. FRACTION AND GENTAMICIN [PDF]

, 2021
Objective: This study aimed to design a formula using Design-Expert software to obtain optimal Self-Nanoemulsifying Drug Delivery System (SNEDDS) formulas and to analyze nanospray characteristics of optimal SNEDDS. Methods: The study began with preparing
APRIDAMAYANTI, PRATIWI, PRATIWI, LIZA, SARI, RAFIKA   +2 more
core   +3 more sources

Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution [PDF]

, 2013
BACKGROUND: Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It is recommended to be taken with milk to enhance its solubility and bioavailability.
Ketan Patel, Pradeep Vavia, Vidur Sarma
core   +2 more sources

Propolis‐Based Hybrid Nanoflowers as Multifunctional Nanozymes: Structural Integration of Polyphenols for Enhanced Catalytic and Antioxidant Activity

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT Propolis is a polyphenol‐rich natural resin with well‐documented antioxidant activity; however, its practical application is restricted by poor aqueous solubility and limited stability. Herein, propolis‐based organic–inorganic hybrid nanoflowers (Prp‐Nfs) were synthesized by integrating a propolis extract into a Cu3(PO4)2·3H2O matrix under ...
Cevahir Altinkaynak, Fatih Kirmizikar
wiley   +1 more source

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Nanomaterials, 2021
Hypertension is a cardiovascular disease that needs long-term medication. Oral delivery is the most common route for the administration of drugs. The present research is to develop piperine self-nanoemulsifying drug delivery system (PE-SNEDDS) using ...
Ameeduzzafar Zafar, Syed Sarim Imam, Nabil K. Alruwaili, Omar Awad Alsaidan, Mohammed H. Elkomy, Mohammed M. Ghoneim, Sultan Alshehri, Ahmed Mahmoud Abdelhaleem Ali, Khalid Saad Alharbi, Mohd Yasir, Kaveripakkam M. Noorulla, Sami I. Alzarea, Abdullah S. Alanazi   +12 more
doaj   +1 more source

Pengaruh Peningkatan Tween 20 Sebagaisurfaktan Terhadapkarakteristik Dan Kestabilan Fisik Sediaanselfnanoemulsifying Drug Delivery System (Snedds) Simvastatin [PDF]

, 2017
SARI Simvastatin merupakan golongan obat BCS (Biopharmaceutics Classification System) kelas II dengan efek anti kolesterol.Simvastatin memiliki permeabilitas yang baik didalam saluran cerna, namun kelarutannya buruk didalam air.Beberapa sediaan dibuat ...
Ananda, N. C. (Novelia), Sulaiman, T. N. (T), Suwarmi, S. (Suwarmi)   +2 more
core  

A Hybrid Nanosystem for Prostate Cancer Therapy: Codelivery of Enzalutamide and Curcumin via Selenium‐Embedded Mesoporous Silica and Chitosan Nanoparticles

ChemistryOpen, Volume 15, Issue 3, March 2026.
Herein, solvent extraction was selected for cetyltrimethylammonium bromide removal and the development of optimized Se‐embedded mesoporous silica nanoparticles, which were loaded with enzalutamide. Additionally, to improve the anticancer activity of Se@MSNPs‐Enz and curcumin bioavailability, curcumin‐loaded chitosan nanoparticles were prepared. This pH‐
Zahra Tavakoli, Khosro Khajeh, Bijan Ranjbar   +2 more
wiley   +1 more source