Development of novel nanoemulsions as delivery systems : A thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology at Massey University, New Zealand [PDF]
Listed in 2016 Dean's List of Exceptional ThesesIn the past decades, emulsions have been widely used as delivery systems for incorporating bioactive compounds into foods.
Teo, Anges Hwee Ming
core
The present study aims at evaluating the ability of a gastro-intestinal in vitro lipolysis model to predict the performance of two lipid formulations and a conventional tablet containing a poorly soluble drug, cinnarizine, in dogs, both in the fasted and fed state. A self-nano-emulsifying drug delivery system (SNEDDS) was either dosed in a hard gelatin
Christophersen, Philip Carsten B +6 more
openaire +3 more sources
Design and Evaluation of Self-Nanoemulsifying Drug Delivery System of Flutamide [PDF]
Flutamide (FLT) is an antiandrogen drug for the treatment of prostate cancer. It has the drawback of poor water solubility and needs enhancement of its dissolution rate in simulated gastric fluids.
Jeevana, Jyothi B, Sreelakshmi, K
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THE DISSOLUTION AND DIFFUSION OF FUROSEMIDE ON SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) [PDF]
Furosemide a diuretic exhibits low solubility in water and low bioavailability. The purpose of this study was to determine the effect SNEDDS formation to dissolution and diffusion of furosemide.
Martien, Ronny +3 more
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Administration of natural oil extracts suffers from low oral bioavailability and anti-proliferative activity. Self-nanoemulsifying drug delivery systems (SNEDDSs) are novel formulations to improvement of the efficacy of poorly water-soluble compounds. In
R. Nazari-Vanani +3 more
doaj +1 more source
Formulasi dan Aktivitas Antibakteri Gel Hand Sanitizer Ekstrak Air Daun Sirih Merah [PDF]
Latar Belakang: Tuntutan zaman mengharuskan manusia untuk menjaga kesehatannya agar terhindar dari penyakit. Salah satunya dengan menggunakan pembersih tangan. Hand sanitizer hadir sebagai solusi dari permasalahan tersebut.
Milala, Alasen Sembiring +2 more
core
Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline
The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral ...
Mohammad Akhlaquer Rahman +1 more
doaj +1 more source
During the last decades, much attention has been focused on SNEDDS approach to resolve concerns of BCS II class drugs with accentuation on upgrading the solubility and bioavailability. The present hypothesis confirms the theory that SNEDDS can reduce the
Ravinder Verma, Deepak Kaushik
doaj +1 more source
Self Nanoemulsions for Oral Drug Delivery: A Comprehensive Review [PDF]
Nanotechnology is firmly acknowledged as significant methodology in drug conveyance that could impact the remedial exhibition of hydrophobic medications.
Kumar Pradeep, Prakash Satya
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Cell-penetrating self-nanoemulsifying drug delivery systems (SNEDDS) for oral gene delivery
Objective: The aim of study was to investigate whether cell-penetrating peptides could amplify cellular uptake of plasmid DNA (pDNA) loaded self-nanoemulsifying drug delivery systems (SNEDDS) by mucosal epithelial cells, thereby enhancing transfection efficiency.
Arshad, Mahmood +6 more
openaire +2 more sources

