Sequence–Activity Relationships for the Snf7 Insecticidal dsRNA in Chrysomelidae [PDF]
Frontiers in Plant Science, 2020 The responsiveness of insects to oral delivery of insecticidal dsRNA has been shown to be dependent on dsRNA length and sequence match. Previous work with the western corn rootworm (WCR, Diabrotica virgifera virgifera; Coleoptera: Chrysomelidae ...
Pamela Bachman +5 more
doaj +3 more sources
Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments
eLife, 2015 The endosomal sorting complexes required for transport (ESCRTs) constitute hetero-oligomeric machines that catalyze multiple topologically similar membrane-remodeling processes.
Shaogeng Tang +7 more
doaj +3 more sources
ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons [PDF]
Molecular Brain, 2011 Backgrounds Endosomal sorting complex required for transport (ESCRT) is involved in several fundamental cellular processes and human diseases. Many mammalian ESCRT proteins have multiple isoforms but their precise functions remain largely unknown ...
Lee Jin-A +5 more
doaj +6 more sources
Ultrastructural changes caused by Snf7 RNAi in larval enterocytes of western corn rootworm (Diabrotica virgifera virgifera Le Conte). [PDF]
PLoS ONE, 2014 The high sensitivity to oral RNA interference (RNAi) of western corn rootworm (WCR, Diabrotica virgifera virgifera Le Conte) provides a novel tool for pest control.
Juraj Koči +5 more
doaj +4 more sources
Membrane binding of a cyanobacterial ESCRT-III protein crucially involves the helix α1-3 hairpin conserved in all superfamily members. [PDF]
Protein SciAbstract IM30, the inner membrane‐associated protein of 30 kDa (also known as Vipp1) is essential for thylakoid membrane biogenesis and/or maintenance in chloroplasts and cyanobacteria. IM30 and its bacterial homolog PspA belong to the ESCRT‐III superfamily, proteins previously thought to be restricted to eukaryotes and archaea.
Schlösser L +16 more
europepmc +3 more sources
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1. [PDF]
FEBS LettTgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Nakatsuji T +5 more
europepmc +2 more sources
Lactobacillus agilis SNF7 Presents Excellent Antibacteria and Anti-Inflammation Properties in Mouse Diarrhea Induced by Escherichia coli. [PDF]
Int J Mol SciEscherichia coli (E. coli) is a common pathogen that causes diarrhea in newborns and animals. Antibiotics are typically used to treat bacterial diarrhea, a global intestinal health issue. Probiotics have gained interest as a potential substitute for antibiotics in the management of E. coli-induced diarrhea and present novel therapeutic options. In this
Feng M +11 more
europepmc +3 more sources
Crucial role of Snf7-3 in synaptic function and cognitive behavior revealed by conventional and conditional knockout mouse models. [PDF]
NeuroscienceSnf7-3 is a crucial component of the endosomal sorting complexes required for transport (ESCRT) pathway, playing a vital role in endolysosomal functions. To elucidate the role of Snf7-3 in vivo, we developed conventional-like and conditional Snf7-3 knockout (KO) mouse models using a "Knockout-first" strategy.
Kim H +12 more
europepmc +3 more sources
Mechanisms of negative membrane curvature sensing and generation by ESCRT III subunit Snf7 [PDF]
Protein Science, 2020 AbstractCertain proteins have the propensity to bind to negatively curved membranes and generate negative membrane curvature. The mechanism of action of these proteins is much less studied and understood than those that sense and generate positive curvature.
Binod Nepal +2 more
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Structure and function of human Vps20 and Snf7 proteins [PDF]
Biochemical Journal, 2004 Snf7p (sucrose non-fermenting) and Vps20p (vacuolar protein-sorting) are small coil-coiled proteins involved in yeast MVB (multivesicular body) structure, formation and function. In the present study, we report the identification of three human homologues of yeast Snf7p, designated hSnf7-1, hSnf7-2 and hSnf7-3, and a single human Vps20p homologue ...
Jeremy W, Peck +2 more
openaire +2 more sources