Results 1 to 10 of about 15,243 (207)

Splicing-related features of introns serve to propel evolution. [PDF]

open access: yesPLoS ONE, 2013
The role of spliceosomal intronic structures played in evolution has only begun to be elucidated. Comparative genomic analyses of fungal snoRNA sequences, which are often contained within introns and/or exons, revealed that about one-third of snoRNA ...
Yuping Luo   +7 more
doaj   +1 more source

SNORA14A inhibits hepatoblastoma cell proliferation by regulating SDHB-mediated succinate metabolism

open access: yesCell Death Discovery, 2023
Hepatoblastoma (HB) is the most common paediatric liver malignancy. Dysregulation of small nucleolar RNAs (snoRNAs) is a critical inducer of tumour initiation and progression. However, the association between snoRNAs and HB remains unknown.
Jiabei Zhu   +12 more
doaj   +1 more source

Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: NIR was identified as an inhibitor of histone acetyltransferase and it represses transcriptional activation of p53. NIR is predominantly localized in the nucleolus and known as Noc2p, which is involved in the maturation of the 60S ribosomal ...
Jianguo Wu   +7 more
doaj   +1 more source

Identification of Eight Small Nucleolar RNAs as Survival Biomarkers and Their Clinical Significance in Gastric Cancer

open access: yesFrontiers in Oncology, 2019
Gastric cancer is one of most common cancers worldwide. Studies have shown that small nucleolar RNAs (snoRNAs) play important roles in several cancers. In this study, we analyzed the snoRNAs that were differentially expressed between gastric tumors and ...
Xuning Wang   +7 more
doaj   +1 more source

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex [PDF]

open access: gold, 2022
Cai Han   +10 more
openalex   +1 more source

MicroRNA-like snoRNA-Derived RNAs (sdRNAs) Promote Castration-Resistant Prostate Cancer [PDF]

open access: gold, 2022
Alexander B. Coley   +24 more
openalex   +1 more source

snoRNA box C/D levels in leukemia cells in chromosomal abnormalities after irradiation

open access: yesСибирский онкологический журнал
The study objective. This paper reviews the express of C/D box snoRNAs (small nucleolar RNAs) and possibility of their use as biomarkers of radioresistance in chromosomal abnormalities. Material and Methods.
E. V. Rastorgueva   +7 more
doaj   +1 more source

Cl gene cluster encoding several small nucleolar RNAs: a comparison amongst trypanosomatids

open access: yesMemorias do Instituto Oswaldo Cruz, 2009
Small nucleolar RNAs (snoRNAs) are small non-coding RNAs that modify RNA molecules such as rRNA and snRNA by guiding 2'-O-ribose methylation (C/D box snoRNA family) and pseudouridylation reactions (H/ACA snoRNA family). H/ACA snoRNAs are also involved in
Paola Nocua   +3 more
doaj   +1 more source

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