Results 11 to 20 of about 15,041 (173)

Annotation of snoRNA abundance across human tissues reveals complex snoRNA-host gene relationships [PDF]

open access: yesGenome Biology, 2021
Background Small nucleolar RNAs (snoRNAs) are mid-size non-coding RNAs required for ribosomal RNA modification, implying a ubiquitous tissue distribution linked to ribosome synthesis.
Étienne Fafard-Couture   +4 more
doaj   +4 more sources

Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs [PDF]

open access: yesBMC Genomics, 2009
Background Small nucleolar RNAs (snoRNAs) represent one of the largest groups of functionally diverse trans-acting non-protein-coding (npc) RNAs currently known in eukaryotic cells.
Guan Dao-Gang   +4 more
doaj   +3 more sources

Emerging Functions for snoRNAs and snoRNA-Derived Fragments [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The widespread implementation of mass sequencing has revealed a diverse landscape of small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts of degradation, there are nevertheless metabolically stable fragments derived from tRNAs, rRNAs, snoRNAs, and other non-coding RNA, with a number of examples of the production ...
Maliha Wajahat   +2 more
openaire   +3 more sources

SnoRNA guide activities: real and ambiguous [PDF]

open access: yesRNA, 2021
In eukaryotes, rRNAs and spliceosomal snRNAs are heavily modified post-transcriptionally. Pseudouridylation and 2′- O -methylation are the most abundant types of RNA modifications. They are mediated by modification guide RNAs, also known as small nucleolar (sno)RNAs and small Cajal body ...
Deryusheva, Svetlana   +2 more
openaire   +3 more sources

snoRNAs Offer Novel Insight and Promising Perspectives for Lung Cancer Understanding and Management

open access: yesCells, 2020
Small nucleolar RNAs (snoRNAs) are non-coding RNAs localized in the nucleolus, where they participate in the cleavage and chemical modification of ribosomal RNAs.
Nour-El-Houda Mourksi   +4 more
doaj   +1 more source

Plant snoRNA database [PDF]

open access: yesNucleic Acids Research, 2003
The Plant snoRNA database (http://www.scri.sari.ac.uk/plant_snoRNA/) provides information on small nucleolar RNAs from Arabidopsis and eighteen other plant species. Information includes sequences, expression data, methylation and pseudouridylation target modification sites, initial gene organization (polycistronic, single gene and intronic) and the ...
John W. S. Brown   +9 more
openaire   +3 more sources

Synergistic interaction network between the snR30 RNP, Utp23, and ribosomal RNA during ribosome synthesis

open access: yesRNA Biology, 2022
snR30/U17 is a highly conserved H/ACA RNA that is required for maturation of the small ribosomal subunit in eukaryotes. By base-pairing to the expansion segment 6 (ES6) of 18S ribosomal RNA (rRNA), the snR30 H/ACA Ribonucleoprotein (RNP) indirectly ...
Timothy J. Vos, Ute Kothe
doaj   +1 more source

The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1

open access: yesCell Discovery, 2022
Long noncoding RNAs (lncRNAs) are usually 5′ capped and 3′ polyadenylated, similar to most typical mRNAs. However, recent studies revealed a type of snoRNA-related lncRNA with unique structures, leading to questions on how they are processed and how they
Wei Huang   +11 more
doaj   +1 more source

Regulation of Alternative Splicing by snoRNAs [PDF]

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2006
The SNURF-SNRPN locus located on chromosome 15 is maternally imprinted and generates a large transcript containing at least 148 exons. Loss of the paternal allele causes Prader-Willi syndrome (PWS). The 3' end of the transcript harbors several evolutionarily conserved C/D box small nucleolar RNAs (snoRNAs) that are tissue-specifically expressed.
S, Kishore, S, Stamm
openaire   +2 more sources

SnoRNA copy regulation affects family size, genomic location and family abundance levels

open access: yesBMC Genomics, 2021
Background Small nucleolar RNAs (snoRNAs) are an abundant class of noncoding RNAs present in all eukaryotes and best known for their involvement in ribosome biogenesis.
Danny Bergeron   +6 more
doaj   +1 more source

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