Results 21 to 30 of about 15,243 (207)
Computational limitations and future needs to unravel the full potential of 2’-O-methylation and C/D box snoRNAs [PDF]
RNA BiologyThis review evaluates the current state of C/D snoRNA databases and prediction tools in relation to 2’-O-methylation (2'-O-Me). It highlights the limitations of existing resources in accurately annotating and predicting guide snoRNAs, particularly for ...
Christian Ramirez +4 more
doaj +2 more sources
Genome Biology, 2000 Small RNAs involved in rRNA methylation and ribosome biogenesis have been found in Archaea.
Rachel B. Brem
openalex +2 more sources
Evaluation of Expression and Clinicopathological Relevance of Small Nucleolar RNAs (snoRNAs) in Invasive Breast Cancer. [PDF]
Noncoding RNAZáveský L +7 more
europepmc +3 more sources
Emerging Functions for snoRNAs and snoRNA-Derived Fragments [PDF]
International Journal of Molecular Sciences, 2021 The widespread implementation of mass sequencing has revealed a diverse landscape of small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts of degradation, there are nevertheless metabolically stable fragments derived from tRNAs, rRNAs, snoRNAs, and other non-coding RNA, with a number of examples of the production ...
Maliha Wajahat +2 more
openaire +4 more sources
Distinct Pathways for snoRNA and mRNA Termination [PDF]
Molecular Cell, 2006 Transcription termination at mRNA genes is linked to polyadenylation. Cleavage at the poly(A) site generates an entry point for the Rat1/Xrn2 exonuclease, which degrades the downstream transcript to promote termination. Small nucleolar RNAs (snoRNAs) are also transcribed by RNA polymerase II but are not polyadenylated.
Minkyu Kim +5 more
openalex +3 more sources
SnoRNA guide activities: real and ambiguous [PDF]
RNA, 2021 In eukaryotes, rRNAs and spliceosomal snRNAs are heavily modified post-transcriptionally. Pseudouridylation and 2′- O -methylation are the most abundant types of RNA modifications. They are mediated by modification guide RNAs, also known as small nucleolar (sno)RNAs and small Cajal body ...
Deryusheva, Svetlana +2 more
openaire +3 more sources
Prader-Willi syndrome: reflections on seminal studies and future therapies [PDF]
Open Biology, 2020 Prader-Willi syndrome (PWS) is caused by the loss of function of the paternally inherited 15q11-q13 locus. This region is governed by genomic imprinting, a phenomenon in which genes are expressed exclusively from one parental allele.
Michael S. Chung +3 more
doaj +1 more source
Nucleic Acids Research, 2003 The Plant snoRNA database (http://www.scri.sari.ac.uk/plant_snoRNA/) provides information on small nucleolar RNAs from Arabidopsis and eighteen other plant species. Information includes sequences, expression data, methylation and pseudouridylation target modification sites, initial gene organization (polycistronic, single gene and intronic) and the ...
John W S, Brown +9 more
openaire +2 more sources
RNA Biology, 2022 snR30/U17 is a highly conserved H/ACA RNA that is required for maturation of the small ribosomal subunit in eukaryotes. By base-pairing to the expansion segment 6 (ES6) of 18S ribosomal RNA (rRNA), the snR30 H/ACA Ribonucleoprotein (RNP) indirectly ...
Timothy J. Vos, Ute Kothe
doaj +1 more source
Regulation of Alternative Splicing by snoRNAs [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2006 The SNURF-SNRPN locus located on chromosome 15 is maternally imprinted and generates a large transcript containing at least 148 exons. Loss of the paternal allele causes Prader-Willi syndrome (PWS). The 3' end of the transcript harbors several evolutionarily conserved C/D box small nucleolar RNAs (snoRNAs) that are tissue-specifically expressed.
Shivendra Kishore, Stefan Stamm
openalex +3 more sources