Results 31 to 40 of about 15,243 (207)
Exploring the roles of snoRNA-induced ribosome heterogeneity in equine osteoarthritis. [PDF]
Front Vet SciChabronova A +6 more
europepmc +3 more sources
The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1
Cell Discovery, 2022 Long noncoding RNAs (lncRNAs) are usually 5′ capped and 3′ polyadenylated, similar to most typical mRNAs. However, recent studies revealed a type of snoRNA-related lncRNA with unique structures, leading to questions on how they are processed and how they
Wei Huang +11 more
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SnoRNA in Cancer Progression, Metastasis and Immunotherapy Response
Biology, 2021 Small nucleolar RNA (snoRNA) were one of our earliest recognised classes of non-coding RNA, but were largely ignored by cancer investigators due to an assumption that their activities were confined to the nucleolus. However, as full genome sequences have
Jildou van der Werf +2 more
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Small RNAs derived from snoRNAs [PDF]
RNA, 2009 Small nucleolar RNAs (snoRNAs) guide RNA modification and are localized in nucleoli and Cajal bodies in eukaryotic cells. Components of the RNA silencing pathway associate with these structures, and two recent reports have revealed that a human and a protozoan snoRNA can be processed into miRNA-like RNAs.
Taft, Ryan J. +5 more
openaire +3 more sources
SnoRNA copy regulation affects family size, genomic location and family abundance levels
BMC Genomics, 2021 Background Small nucleolar RNAs (snoRNAs) are an abundant class of noncoding RNAs present in all eukaryotes and best known for their involvement in ribosome biogenesis.
Danny Bergeron +6 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 During spaceflight, astronauts are exposed to various physiological and psychological stressors that have been associated with adverse health effects.
Amit Kumar Rai +15 more
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Phylogenetic distribution of plant snoRNA families [PDF]
BMC Genomics, 2016 Small nucleolar RNAs (snoRNAs) are one of the most ancient families amongst non-protein-coding RNAs. They are ubiquitous in Archaea and Eukarya but absent in bacteria. Their main function is to target chemical modifications of ribosomal RNAs. They fall into two classes, box C/D snoRNAs and box H/ACA snoRNAs, which are clearly distinguished by conserved
Deblina Patra Bhattacharya +5 more
openaire +4 more sources
U8 variants on the brain: a small nucleolar RNA and human disease
RNA Biology, 2022 Small nucleolar RNAs (snoRNAs) are non-coding RNAs vital for ribosomal RNA (rRNA) maturation. The U8 snoRNA, encoded by the SNORD118 gene in humans, is an atypical C/D box snoRNA as it promotes rRNA cleavage rather than 2′–O–methylation and is unique to ...
Emily J. McFadden, Susan J. Baserga
doaj +1 more source
snoRNA U17 Regulates Cellular Cholesterol Trafficking [PDF]
Cell Metabolism, 2015 Cholesterol is required for the growth and viability of mammalian cells and is an obligate precursor for steroid hormone synthesis. Using a loss-of-function screen for mutants with defects in intracellular cholesterol trafficking, a Chinese hamster ovary cell mutant with haploinsufficiency of the U17 snoRNA was isolated.
Jinn, Sarah +11 more
openaire +2 more sources
U3 snoRNA genes are multi-copy and frequently linked to U5 snRNA genes in
BMC Genomics, 2009 Background U3 snoRNA is a box C/D small nucleolar RNA (snoRNA) involved in the processing events that liberate 18S rRNA from the ribosomal RNA precursor (pre-rRNA). Although U3 snoRNA is present in all eukaryotic organisms, most investigations of it have
Charette J Michael, Gray Michael W
doaj +1 more source