Results 21 to 30 of about 74,278 (259)

Genetic analysis of products of conception using a HLPA/SNP-array strategy

Molecular Cytogenetics, 2019
Background Fetal chromosomal abnormalities was the most frequent cause of miscarriage, and the traditional testing method G-banded karyotyping has limitations.
Jun Mao, Huiling Wang, Haibo Li, Xiaoyan Song, Ting Wang, Jingjing Xiang, Hong Li   +6 more
doaj   +1 more source

SAQC: SNP Array Quality Control

BMC Bioinformatics, 2011
Background Genome-wide single-nucleotide polymorphism (SNP) arrays containing hundreds of thousands of SNPs from the human genome have proven useful for studying important human genome questions.
Li Ling-Hui, Lin Chien-Wei, Chen Chun-Houh, Kang Meijyh, Lin Hsin-Chi, Yang Hsin-Chou, Wu Jer-Yuarn, Chen Yuan-Tsong, Pan Wen-Harn   +8 more
doaj   +1 more source

SNPs ANALYSIS AS A TOOL IN MOLECULAR GENETICS DIAGNOSTICS

Majalah Kedokteran Andalas, 2015
AbstrakSingle Nucleotide Polymorphism (SNP) merupakan variasi genetik yang ditemukan pada lebih dari 1% populasi. Haplotipe, yang merupakan sekelompok SNP atau alel dalam satu kromosom, dapat di turunkan ke generasi selanjutnya dan dapat digunakan untuk ...
Dewi Rusnita
doaj   +1 more source

Development and Validation of an Open Access SNP Array for Nile Tilapia (Oreochromis niloticus)

G3: Genes, Genomes, Genetics, 2020
Tilapia are among the most important farmed fish species worldwide, and are fundamental for the food security of many developing countries. Several genetically improved Nile tilapia (Oreochromis niloticus) strains exist, such as the iconic Genetically ...
Carolina Peñaloza, Diego Robledo, Agustin Barría, Trọng Quốc Trịnh, Mahirah Mahmuddin, Pamela Wiener, John A. H. Benzie, Ross D. Houston   +7 more
doaj   +1 more source

Fetal genetic findings by chromosomal microarray analysis and karyotyping for fetal growth restriction without structural malformations at a territory referral center: 10-year experience

BMC Pregnancy and Childbirth, 2023
Background Prenatal invasive genetic testing is commonly recommended to pregnancies of early-onset FGR or FGR combined with a structural defect. Our study aimed to explore the genetic findings for FGR without structural malformations according to ...
Xiaoqing Wu, Shuqiong He, Ying Li, Danhua Guo, Xuemei Chen, Bin Liang, Meiying Wang, Hailong Huang, Liangpu Xu   +8 more
doaj   +1 more source

A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array

BMC Bioinformatics, 2007
Background DNA copy number aberration (CNA) is one of the key characteristics of cancer cells. Recent studies demonstrated the feasibility of utilizing high density single nucleotide polymorphism (SNP) genotyping arrays to detect CNA.
Bailey Dione K, Jacobs Sharoni, Chen Zugen, Li Ker-Chau, Sun Wei, Ye Hui, Yu Tianwei, Wong David T, Zhou Xiaofeng   +8 more
doaj   +1 more source

Development and validation of a 20K single nucleotide polymorphism (SNP) whole genome genotyping array for apple (Malus × domestica Borkh). [PDF]

PLoS ONE, 2014
High-density SNP arrays for genome-wide assessment of allelic variation have made high resolution genetic characterization of crop germplasm feasible. A medium density array for apple, the IRSC 8K SNP array, has been successfully developed and used for ...
Luca Bianco, Alessandro Cestaro, Daniel James Sargent, Elisa Banchi, Sophia Derdak, Mario Di Guardo, Silvio Salvi, Johannes Jansen, Roberto Viola, Ivo Gut, Francois Laurens, David Chagné, Riccardo Velasco, Eric van de Weg, Michela Troggio   +14 more
doaj   +1 more source

Clinical Utility and the Yield of Single Nucleotide Polymorphism Array in Prenatal Diagnosis of Fetal Central Nervous System Abnormalities

Frontiers in Molecular Biosciences, 2021
Applying single nucleotide polymorphism (SNP) array to identify the etiology of fetal central nervous system (CNS) abnormality, and exploring its association with chromosomal abnormalities, copy number variations, and obstetrical outcome.
Meiying Cai, Hailong Huang, Liangpu Xu, Na Lin   +3 more
doaj   +1 more source

High concordance between next-generation sequencing and single-nucleotide polymorphism array in preimplantation genetic testing for aneuploidy

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: This study aimed to compare the use of next-generation sequencing (NGS) and single-nucleotide polymorphism (SNP) array in preimplantation genetic testing for aneuploidy (PGT-A) in the same blastocyst.
Zhanhui Ou, Zhiheng Chen, Yu Deng, Ling Sun   +3 more
doaj   +1 more source

Development and Evaluation of a High-Throughput Single-Nucleotide Polymorphism Array for Large Yellow Croaker (Larimichthys crocea)

Frontiers in Genetics, 2020
High-density single-nucleotide polymorphism (SNP) genotyping array is an essential tool for genetic analyses of animals and plants. Large yellow croaker (Larimichthys crocea) is one of the most commercially important marine fish species in China ...
Tao Zhou, Baohua Chen, Qiaozhen Ke, Qiaozhen Ke, Ji Zhao, Fei Pu, Yidi Wu, Lin Chen, Zhixiong Zhou, Yulin Bai, Ying Pan, Ying Pan, Jie Gong, Weiqiang Zheng, Peng Xu, Peng Xu   +15 more
doaj   +1 more source