Results 61 to 70 of about 1,566,477 (261)

Evaluating Translocation Gene Fusions by SNP Array Data [PDF]

Cancer Informatics, 2011
Somatic cell genetic alterations are a hallmark of tumor development and progression. Although various technologies have been developed and utilized to identify genetic aberrations, identifying genetic translocations at the chromosomal level is still a challenging task. High density SNP microarrays are useful to measure DNA copy number variation (CNV)
Hong Liu, Asher Zilberstein, Pascal Pannier, Frederic Fleche, Christopher Arendt, Christoph Lengauer, Chang S. Hahn   +6 more
doaj   +5 more sources

Development of a Medium Density Combined-Species SNP Array for Pacific and European Oysters (Crassostrea gigas and Ostrea edulis)

G3: Genes, Genomes, Genetics, 2017
SNP arrays are enabling tools for high-resolution studies of the genetic basis of complex traits in farmed and wild animals. Oysters are of critical importance in many regions from both an ecological and economic perspective, and oyster aquaculture forms

semanticscholar   +1 more source

Performance evaluation of DNA copy number segmentation methods [PDF]

, 2014
A number of bioinformatic or biostatistical methods are available for analyzing DNA copy number profiles measured from microarray or sequencing technologies.
Neuvial, Pierre, Pierre-Jean, Morgane, Rigaill, Guillem   +2 more
core   +2 more sources

Autozygosity Mapping by Genome-wide Single Nucleotide Polymorphism Array Identifies a Novel Homozygous HR Mutation in a Consanguineous Family with Universal Hereditary Hair Loss

International Journal of Dermatology and Venerology, 2021
. Objective:. Isolated hereditary hypotrichosis is caused by mutations in as many as 11 different genes. The conventional mutation detection strategy consists of sequencing of individual candidate genes separately, a time consuming and costly approach ...
Sirous Zeinali, Leila Youssefian, Hassan Vahidnezhad, Amir Hossein Saeidian, Soheila Sotoudeh, Hamideh Bagherian, Jouni Uitto   +6 more
doaj   +1 more source

Utilization of a Wheat55K SNP Array for Mapping of Major QTL for Temporal Expression of the Tiller Number

Frontiers in Plant Science, 2018
Maximum tiller number and productive tiller number are important traits for wheat grain yield, but research involving the temporal expression of tiller number at different quantitative trait loci (QTL) levels is limited.
T. Ren, Yangshan Hu, Yingzi Tang, Chunsheng Li, B. Yan, Z. Ren, F. Tan, Zong-xiang Tang, S. Fu, Zhi Li   +9 more
semanticscholar   +1 more source

Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12. [PDF]

, 2018
Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather ...
Cheng, HH, Delany, ME, Gitter, CL, Kaya, M, May, B, O'Hare, EA, Webb, AE, Youngworth, IA   +7 more
core   +1 more source

High-density 80 K SNP array is a powerful tool for genotyping G. hirsutum accessions and genome analysis

BMC Genomics, 2017
BackgroundHigh-throughput genotyping platforms play important roles in plant genomic studies. Cotton (Gossypium spp.) is the world’s important natural textile fiber and oil crop.
Caiping Cai, Guozhong Zhu, Tianzhen Zhang, Wangzhen Guo   +3 more
semanticscholar   +1 more source

Development of SNP‐genotyping arrays in two shellfish species [PDF]

Molecular Ecology Resources, 2014
AbstractUse of SNPs has been favoured due to their abundance in plant and animal genomes, accompanied by the falling cost and rising throughput capacity for detection and genotyping. Here, we present in vitro (obtained from targeted sequencing) and in silico discovery of SNPs, and the design of medium‐throughput genotyping arrays for two oyster species,
Marion Ballenghien, Philippe Gayral, Philippe Gayral, Emilie Flahauw, Christophe Klopp, Cécile Donnadieu, Lucie Genestout, L. Barbotte, Serge Heurtebise, Estelle Harrang, Pierrick Haffray, Sylvie Lapegue, R. Mahla   +12 more
openaire   +3 more sources

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer

BMC Genomics, 2007
Background Cervical carcinoma develops as a result of multiple genetic alterations. Different studies investigated genomic alterations in cervical cancer mainly by means of metaphase comparative genomic hybridization (mCGH) and microsatellite marker ...
Kenter Gemma G, Gorter Arko, Knijnenburg Jeroen, Szuhai Karoly, van Wezel Tom, Oosting Jan, Kloth Judith N, Fleuren Gert, Jordanova Ekaterina S   +8 more
doaj   +1 more source

CNV discovery using SNP genotyping arrays

Cytogenetic and Genome Research, 2008
Genome-wide single nucleotide polymorphism (SNP) genotyping platforms have made an important contribution to population genetics and genetic epidemiology. Recently there has been a realisation that these SNP platforms can also be used for typing copy number variants (CNVs).
Yau, C, Holmes, C
openaire   +4 more sources