Results 61 to 70 of about 1,520,842 (344)

Hybridization and amplification rate correction for affymetrix SNP arrays [PDF]

BMC Medical Genomics, 2012
Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation may be biased by several factors, including cross-hybridization and training sample batch,
Peichao Peng, Quan Wang, Minping Qian, Minghua Deng, Lin Wan, Lin Wan   +5 more
openaire   +3 more sources

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer

BMC Genomics, 2007
Background Cervical carcinoma develops as a result of multiple genetic alterations. Different studies investigated genomic alterations in cervical cancer mainly by means of metaphase comparative genomic hybridization (mCGH) and microsatellite marker ...
Kenter Gemma G, Gorter Arko, Knijnenburg Jeroen, Szuhai Karoly, van Wezel Tom, Oosting Jan, Kloth Judith N, Fleuren Gert, Jordanova Ekaterina S   +8 more
doaj   +1 more source

Software solutions for the livestock genomics SNP array revolution [PDF]

Animal Genetics, 2015
Since the beginning of the genomic era, the number of available single nucleotide polymorphism (SNP) arrays has grown considerably. In the bovine species alone, 11 SNP chips not completely covered by intellectual property are currently available, and the number is growing.
Stefano Biffani, Alessandra Stella, Alessandra Stella, P. Orozco ter Wengel, Filippo Biscarini, Ezequiel L. Nicolazzi, Nelson Nazzicari, Andrea Caprera   +7 more
openaire   +6 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Development and application of a 1K functional liquid chip for lactation performance in Bactrian camels

Frontiers in Veterinary Science
IntroductionThe advancement of high-throughput, high-quality, flexible, and cost-effective genotyping platforms is crucial for the progress of dairy breeding in Bactrian camels.
Lili Guo, Lili Guo, Lili Guo, Lema Dao, Bin Liu, Jingyu Wang, Zaixia Liu, Zaixia Liu, Fengying Ma, Fengying Ma, Bielige Morigen, Chencheng Chang, Chencheng Chang, Yinbatu Bai, Yinbatu Bai, Yaqiang Guo, Yaqiang Guo, Caixia Shi, Caixia Shi, Junwei Cao, Junwei Cao, Wenguang Zhang, Wenguang Zhang, Wenguang Zhang   +23 more
doaj   +1 more source

Genetic Diversity and Population Structure in a Vitis spp. Core Collection Investigated by SNP Markers

Diversity, 2020
Single nucleotide polymorphism (SNP) genotyping arrays are powerful tools to measure the level of genetic polymorphism within a population. The coming of next-generation sequencing technologies led to identifying thousands and millions of SNP loci useful
Davide Bianchi, Lucio Brancadoro, Gabriella De Lorenzis   +2 more
doaj   +1 more source

Development of a Medium Density Combined-Species SNP Array for Pacific and European Oysters (Crassostrea gigas and Ostrea edulis)

G3: Genes, Genomes, Genetics, 2017
SNP arrays are enabling tools for high-resolution studies of the genetic basis of complex traits in farmed and wild animals. Oysters are of critical importance in many regions from both an ecological and economic perspective, and oyster aquaculture forms

semanticscholar   +1 more source

Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]

BMC Genomics, 2006
Abstract Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Valentina Moskvina, Lyudmila Georgieva, Ivan Nikolov, Michael John Owen, Michael Conlon O'Donovan, George Kirov   +5 more
openaire   +4 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Development and evaluation of a genome‐wide Coffee 8.5K SNP array and its application for high‐density genetic mapping and for investigating the origin of Coffea arabica L.

Plant Biotechnology Journal, 2019
Summary Coffee species such as Coffea canephora P. (Robusta) and C. arabica L. (Arabica) are important cash crops in tropical regions around the world. C.
Virginie Merot‐L'anthoene, R. Tournebize, Olivier Darracq, Vimel Rattina, M. Lepelley, L. Bellanger, Christine Tranchant-Dubreuil, Manon Coulée, Marie Pégard, S. Métairon, Coralie Fournier, P. Stoffelen, S. Janssens, C. Kiwuka, P. Musoli, Ucu Sumirat, H. Legnaté, Jean-Léon Kambale, João Ferreira da Costa Neto, Clara Revel, A. de Kochko, P. Descombes, D. Crouzillat, V. Poncet   +23 more
semanticscholar   +1 more source