Results 1 to 10 of about 221,926 (326)

Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping [PDF]

BMC Genomics, 2021
Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Baowei Li, Yanran Liu, Xiaodan Hao, Jinhua Dong, Limei Chen, Haimei Li, Wei Wu, Ying Liu, Jianxun Wang, Yin Wang, Peifeng Li   +10 more
doaj   +2 more sources

Detecting SARS-CoV-2 variants with SNP genotyping. [PDF]

PLoS ONE, 2021
Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively ...
Helen Harper, Amanda Burridge, Mark Winfield, Adam Finn, Andrew Davidson, David Matthews, Stephanie Hutchings, Barry Vipond, Nisha Jain, COVID-19 Genomics UK (COG-UK) Consortium, Keith Edwards, Gary Barker   +11 more
doaj   +2 more sources

Research note: A low-density SNP genotyping panel for Chinese native chickens [PDF]

Poultry Science
The efficiency of molecular breeding largely depends on the cost of genotyping, which plays an important role in breeding and population genetic studies.
Jie Wang, Siyuan Xing, Yan Zhou, Jie Liu, Yan Sun, Qiuxia Lei, Haixia Han, Wei Liu, Dapeng Li, Fuwei Li, Dingguo Cao   +10 more
doaj   +2 more sources

Design and validation of a 63K genome-wide SNP-genotyping platform for caribou/reindeer (Rangifer tarandus) [PDF]

BMC Genomics, 2022
Background Development of large single nucleotide polymorphism (SNP) arrays can make genomic data promptly available for conservation problematic. Medium and high-density panels can be designed with sufficient coverage to offer a genome-wide perspective ...
Alexandra Carrier, Julien Prunier, William Poisson, Mallorie Trottier-Lavoie, Isabelle Gilbert, Maria Cavedon, Kisun Pokharel, Juha Kantanen, Marco Musiani, Steeve D. Côté, Vicky Albert, Joëlle Taillon, Vincent Bourret, Arnaud Droit, Claude Robert   +14 more
doaj   +2 more sources

Development and Assessment of SNP Genotyping Arrays for Citrus and Its Close Relatives [PDF]

Plants
Rapid advancements in technologies provide various tools to analyze fruit crop genomes to better understand genetic diversity and relationships and aid in breeding.
Yoko Hiraoka, Sergio Pietro Ferrante, Guohong Albert Wu, Claire T. Federici, Mikeal L. Roose   +4 more
doaj   +2 more sources

A multisite SNP genotyping and macrolide susceptibility gene method for Mycoplasma pneumoniae based on MALDI-TOF MS

iScience, 2021
Summary: In this study, a multisite SNP genotyping and macrolide (ML) susceptibility gene test method for Mycoplasma pneumoniae (M. pneumoniae) was developed based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF
Fei Zhao, Jianzhong Zhang, Xuemei Wang, Liyong Liu, Jie Gong, Zhixiang Zhai, Lihua He, Fanliang Meng, Di Xiao   +8 more
doaj   +1 more source

Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Berg, Andrea von, Bufe, Albrecht, Depner, Martin, Frischer, Thomas, Genuneit, Jon, Gut, Ivo G., Heinzmann, Andrea, Illig, Thomas, Kabesch, Michael, Klopp, Norman, Kumar, Ashish, Lathrop, Mark, Laub, Otto, Liang, Liming, Michel, Sven, Mutius, Erika von, Rietschel, Ernst, Ruether, Andreas, Schedel, Michaela, Schreiber, Stefan, Simma, Burkhard, Vogelberg, Christian   +21 more
core   +15 more sources

Rapid and simple SNP genotyping for Bordetella pertussis epidemic strain MT27 based on a multiplexed single-base extension assay

Scientific Reports, 2021
Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain
Kazunari Kamachi, Shu-Man Yao, Chuen-Sheue Chiang, Kentaro Koide, Nao Otsuka, Keigo Shibayama   +5 more
doaj   +1 more source

Comparison of sequencing-based and array-based genotyping platforms for genomic prediction of maize hybrid performance

Crop Journal, 2023
Genomic selection (GS) is a powerful tool for improving genetic gain in maize breeding. However, its routine application in large-scale breeding pipelines is limited by the high cost of genotyping platforms.
Guangning Yu, Yanru Cui, Yuxin Jiao, Kai Zhou, Xin Wang, Wenyan Yang, Yiyi Xu, Kun Yang, Xuecai Zhang, Pengcheng Li, Zefeng Yang, Yang Xu, Chenwu Xu   +12 more
doaj   +1 more source

Imputation strategies for genomic prediction using nanopore sequencing

BMC Biology, 2023
Background Genomic prediction describes the use of SNP genotypes to predict complex traits and has been widely applied in humans and agricultural species.
H. J. Lamb, L. T. Nguyen, J. P. Copley, B. N. Engle, B. J. Hayes, E. M. Ross   +5 more
doaj   +1 more source