A model selection approach to genome wide association studies [PDF]
arXiv, 2010 For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statistical considerations which clearly show that in case of complex traits the approach based on multiple regression or generalized linear models is preferable
arxiv
Genotyping and drug response: Use of single nucleotide polymorphisms (SNPs) versus haplotypes to predict albuterol efficacy [PDF]
, 2001 Suzanne Schubbert
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Learning the optimal scale for GWAS through hierarchical SNP aggregation [PDF]
arXiv, 2017 Motivation: Genome-Wide Association Studies (GWAS) seek to identify causal genomic variants associated with rare human diseases. The classical statistical approach for detecting these variants is based on univariate hypothesis testing, with healthy individuals being tested against affected individuals at each locus.
arxiv
Multiplex SNP Genotyping Using Locked Nucleic Acid and Microfluidics [PDF]
, 2001 Yoanna Choleva +8 more
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SNP Genotyping Using Single-Tube Fluorescent Bidirectional PCR [PDF]
, 2002 Christy Waterfall, Benjamin D. Cobb
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SNP genotyping in the β2-adrenergic receptor by electronic microchip assay, DHPLC, and direct sequencing [PDF]
, 2002 N. Yoshida +7 more
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Ordered catenation of sequence-tagged sites and multiplexed SNP genotyping by sequencing [PDF]
, 2002 Koichiro Higasa
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Comparison of GenFlex Tag Array and Pyrosequencing in SNP Genotyping [PDF]
, 2003 Daniel C. Chen +5 more
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GenoTriplo: A SNP genotype calling method for triploids
PLOS Computational BiologyAbstractTriploidy is very useful in both aquaculture and some cultivated plants as the induced sterility helps to enhance growth and product quality, as well as acting as a barrier against the contamination of wild populations by escapees. To use genetic information from triploids for academic or breeding purposes, an efficient and robust method to ...
Roche Julien +6 more
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Integration of SNP genotyping and 16S rRNA amplicon sequencing to identify heritable gut microbes in chickens. [PDF]
STAR Protoc, 2023 Zhang J, Feng Y, Hu Y.
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