“Spot-On” SNP Genotyping: Figure 1. [PDF]
Genome Research, 2000 As we enter the post-genomic era, where complete reference genome sequences are a given, analyzing the variation among individual genomes is an area of intense investigation. One of the most common forms of genomic variation is single nucleotide polymorphisms, or SNPs. The “science of SNPs” has become a heavy industry, as evidenced by the proliferation
Michael C. Ellis
openalex +5 more sources
Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping [PDF]
BMC Genomics, 2021 Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Baowei Li +10 more
doaj +2 more sources
genotools SNP MANAGER: A New Software for Automated High-Throughput MALDI-TOF Mass Spectrometry SNP Genotyping [PDF]
BioTechniques, 2001 Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research that provides insights into the most common type of differences between individual genomes.
W. Pusch +4 more
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Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]
BMC Genomics, 2006 Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J +5 more
doaj +4 more sources
Rapid and simple SNP genotyping for Bordetella pertussis epidemic strain MT27 based on a multiplexed single-base extension assay [PDF]
Scientific Reports, 2021 Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain
Kazunari Kamachi +5 more
doaj +2 more sources
High-Throughput SNP Genotyping by SBE/SBH [PDF]
arXiv, 2005 Despite much progress over the past decade, current Single Nucleotide Polymorphism (SNP) genotyping technologies still offer an insufficient degree of multiplexing when required to handle user-selected sets of SNPs. In this paper we propose a new genotyping assay architecture combining multiplexed solution-phase single-base extension (SBE) reactions ...
Ion Măndoiu, Claudia Prăjescu
arxiv +3 more sources
Detecting SARS-CoV-2 variants with SNP genotyping. [PDF]
PLoS ONE, 2021 Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively ...
Helen Harper +11 more
doaj +2 more sources
Design and validation of a 63K genome-wide SNP-genotyping platform for caribou/reindeer (Rangifer tarandus) [PDF]
BMC Genomics, 2022 Background Development of large single nucleotide polymorphism (SNP) arrays can make genomic data promptly available for conservation problematic. Medium and high-density panels can be designed with sufficient coverage to offer a genome-wide perspective ...
Alexandra Carrier +14 more
doaj +2 more sources
Development and Assessment of SNP Genotyping Arrays for Citrus and Its Close Relatives [PDF]
PlantsRapid advancements in technologies provide various tools to analyze fruit crop genomes to better understand genetic diversity and relationships and aid in breeding.
Yoko Hiraoka +4 more
doaj +2 more sources
Research note: A low-density SNP genotyping panel for Chinese native chickens [PDF]
Poultry ScienceThe efficiency of molecular breeding largely depends on the cost of genotyping, which plays an important role in breeding and population genetic studies.
Jie Wang +10 more
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