Results 1 to 10 of about 97,365 (285)

genotools SNP MANAGER: A New Software for Automated High-Throughput MALDI-TOF Mass Spectrometry SNP Genotyping [PDF]

BioTechniques, 2001
Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research that provides insights into the most common type of differences between individual genomes.
W. Pusch, K.-O. Kraeuter, T. Froehlich, Y. Stalgies, M. Kostrzewa   +4 more
doaj   +2 more sources

Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]

BMC Genomics, 2006
Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J, Moskvina Valentina, Georgieva Lyudmila, Nikolov Ivan, Kirov George, O'Donovan Michael C   +5 more
doaj   +4 more sources

Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping

BMC Genomics, 2021
Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Baowei Li, Yanran Liu, Xiaodan Hao, Jinhua Dong, Limei Chen, Haimei Li, Wei Wu, Ying Liu, Jianxun Wang, Yin Wang, Peifeng Li   +10 more
doaj   +1 more source

Rapid and simple SNP genotyping for Bordetella pertussis epidemic strain MT27 based on a multiplexed single-base extension assay

Scientific Reports, 2021
Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain
Kazunari Kamachi, Shu-Man Yao, Chuen-Sheue Chiang, Kentaro Koide, Nao Otsuka, Keigo Shibayama   +5 more
doaj   +1 more source

Development of an Assay to Distinguish Between Genotypes of the Leucyl-Cystinyl Aminopeptidase Gene

Re:GEN Open, 2022
Introduction: The leucyl-cystinyl aminopeptidase gene rs4869317 single nucleotide polymorphism (SNP) is associated with multiple conditions; for example, patients with the rs4869317 TT genotype experiencing septic shock have increased plasma clearance ...
Nayan J. Sarma, Shannon R. Dalton, Saji Vijayan   +2 more
doaj   +1 more source

Imputation strategies for genomic prediction using nanopore sequencing

BMC Biology, 2023
Background Genomic prediction describes the use of SNP genotypes to predict complex traits and has been widely applied in humans and agricultural species.
H. J. Lamb, L. T. Nguyen, J. P. Copley, B. N. Engle, B. J. Hayes, E. M. Ross   +5 more
doaj   +1 more source

Agrigenomic Diversity Unleashed: Current Single Nucleotide Polymorphism Genotyping Methods for the Agricultural Sciences

Applied Biosciences, 2023
Single Nucleotide Polymorphisms (SNPs) are variations that occur at single nucleotides in the genome and are present at an appreciable level in a population.
Roger D. Lawrie, Steven E. Massey
doaj   +1 more source

Genotyping by genome reducing and sequencing for outbred animals. [PDF]

PLoS ONE, 2013
Next-generation sequencing (NGS) approaches are widely used in genome-wide genetic marker discovery and genotyping. However, current NGS approaches are not easy to apply to general outbred populations (human and some major farm animals) for SNP ...
Qiang Chen, Yufang Ma, Yumei Yang, Zhenliang Chen, Rongrong Liao, Xiaoxian Xie, Zhen Wang, Pengfei He, Yingying Tu, Xiangzhe Zhang, Changsuo Yang, Hongjie Yang, Fuqing Yu, Youmin Zheng, Zhiwu Zhang, Qishan Wang, Yuchun Pan   +16 more
doaj   +1 more source

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

Malaria Journal, 2019
Background Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection.
Joseph Fulakeza, Sarah McNitt, Jimmy Vareta, Alex Saidi, Godfrey Mvula, Terrie Taylor, Don P. Mathanga, Dylan S. Small, Jacek Skarbinski, Julie R. Gutman, Karl Seydel   +10 more
doaj   +1 more source

Development of STARP Marker Platform for Flexible SNP Genotyping in Sugarbeet

Agronomy, 2023
Single nucleotide polymorphisms (SNPs) have been widely used for gene identification. Allelic discrimination for an individual SNP with high reliability and flexibility is critical for the accurate detection of beneficial genes linked to specific SNP ...
Muhammad Massub Tehseen, Yaojie Zheng, Nathan A. Wyatt, Melvin D. Bolton, Shengming Yang, Steven S. Xu, Xuehui Li, Chenggen Chu   +7 more
doaj   +1 more source