Results 1 to 10 of about 201,829 (351)
High-Throughput SNP Genotyping by SBE/SBH [PDF]
arXiv, 2005 Despite much progress over the past decade, current Single Nucleotide Polymorphism (SNP) genotyping technologies still offer an insufficient degree of multiplexing when required to handle user-selected sets of SNPs.
Mandoiu, Ion I., Prajescu, Claudia
core +6 more sources
“Spot-On” SNP Genotyping: Figure 1. [PDF]
Genome Research, 2000 As we enter the post-genomic era, where complete reference genome sequences are a given, analyzing the variation among individual genomes is an area of intense investigation. One of the most common forms of genomic variation is single nucleotide polymorphisms, or SNPs. The “science of SNPs” has become a heavy industry, as evidenced by the proliferation
Michael C. Ellis
openalex +5 more sources
Temperature Switch PCR (TSP): Robust assay design for reliable amplification and genotyping of SNPs [PDF]
BMC Genomics, 2009 Background Many research and diagnostic applications rely upon the assay of individual single nucleotide polymorphisms (SNPs). Thus, methods to improve the speed and efficiency for single-marker SNP genotyping are highly desirable.
Mather Diane E +2 more
doaj +5 more sources
Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]
BMC Genomics, 2006 Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J +5 more
doaj +4 more sources
genotools SNP MANAGER: A New Software for Automated High-Throughput MALDI-TOF Mass Spectrometry SNP Genotyping [PDF]
BioTechniques, 2001 Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research that provides insights into the most common type of differences between individual genomes.
W. Pusch +4 more
doaj +2 more sources
High-Throughput SNP Genotyping [PDF]
ChemInform, 2002 Whole genome approaches using single nucleotide polymorphism (SNP) markers have the potential to transform complex disease genetics and expedite pharmacogenetics research.
Gibson, Neil, Jenkins, Suzanne
core +7 more sources
Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping [PDF]
BMC Genomics, 2021 Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Baowei Li +10 more
doaj +2 more sources
Silhouette scores for assessment of SNP genotype clusters [PDF]
BMC Genomics, 2005 Background High-throughput genotyping of single nucleotide polymorphisms (SNPs) generates large amounts of data. In many SNP genotyping assays, the genotype assignment is based on scatter plots of signals corresponding to the two SNP alleles. In a robust
Jonsson Mats +3 more
doaj +5 more sources
SNP high-throughput screening in grapevine using the SNPlex™ genotyping system [PDF]
BMC Plant Biology, 2008 Background Until recently, only a small number of low- and mid-throughput methods have been used for single nucleotide polymorphism (SNP) discovery and genotyping in grapevine (Vitis vinifera L.).
Velasco Riccardo +6 more
doaj +2 more sources
Scientific Reports, 2021 Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain
Kazunari Kamachi +5 more
doaj +1 more source