Results 1 to 10 of about 220,745 (323)
Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping [PDF]
BMC Genomics, 2021 Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Baowei Li +10 more
doaj +2 more sources
Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]
BMC Genomics, 2006 Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J +5 more
doaj +3 more sources
Detecting SARS-CoV-2 variants with SNP genotyping. [PDF]
PLoS ONE, 2021 Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively ...
Helen Harper +11 more
doaj +2 more sources
Research note: A low-density SNP genotyping panel for Chinese native chickens [PDF]
Poultry ScienceThe efficiency of molecular breeding largely depends on the cost of genotyping, which plays an important role in breeding and population genetic studies.
Jie Wang +10 more
doaj +2 more sources
Design and validation of a 63K genome-wide SNP-genotyping platform for caribou/reindeer (Rangifer tarandus) [PDF]
BMC Genomics, 2022 Background Development of large single nucleotide polymorphism (SNP) arrays can make genomic data promptly available for conservation problematic. Medium and high-density panels can be designed with sufficient coverage to offer a genome-wide perspective ...
Alexandra Carrier +14 more
doaj +2 more sources
Development and Assessment of SNP Genotyping Arrays for Citrus and Its Close Relatives [PDF]
PlantsRapid advancements in technologies provide various tools to analyze fruit crop genomes to better understand genetic diversity and relationships and aid in breeding.
Yoko Hiraoka +4 more
doaj +2 more sources
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. [PDF]
, 2012 Genome-wide association studies identified a PTGER4 expression-modulating region on chromosome 5p13.1 as Crohn's disease (CD) susceptibility region. The study aim was to test this association in a large cohort of patients with inflammatory bowel disease (
Achkar, Jean-Paul +14 more
core +33 more sources
iScience, 2021 Summary: In this study, a multisite SNP genotyping and macrolide (ML) susceptibility gene test method for Mycoplasma pneumoniae (M. pneumoniae) was developed based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF
Fei Zhao +8 more
doaj +1 more source
High‐Throughput SNP Genotyping [PDF]
ChemInform, 2002 AbstractWhole genome approaches using single nucleotide polymorphism (SNP) markers have the potential to transform complex disease genetics and expedite pharmacogenetics research. This has led to a requirement for high‐throughput SNP genotyping platforms. Development of a successful high‐throughput genotyping platform depends on coupling reliable assay
Jenkins, Suzanne, Gibson, Neil
openaire +2 more sources
Scientific Reports, 2021 Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain
Kazunari Kamachi +5 more
doaj +1 more source