“Spot-On” SNP Genotyping: Figure 1. [PDF]
Genome Research, 2000 As we enter the post-genomic era, where complete reference genome sequences are a given, analyzing the variation among individual genomes is an area of intense investigation. One of the most common forms of genomic variation is single nucleotide polymorphisms, or SNPs. The “science of SNPs” has become a heavy industry, as evidenced by the proliferation
Michael C. Ellis
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Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping [PDF]
BMC Genomics, 2021 Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Baowei Li +10 more
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Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]
BMC Genomics, 2006 Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J +5 more
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genotools SNP MANAGER: A New Software for Automated High-Throughput MALDI-TOF Mass Spectrometry SNP Genotyping [PDF]
BioTechniques, 2001 Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research that provides insights into the most common type of differences between individual genomes.
W. Pusch +4 more
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A multisite SNP genotyping and macrolide susceptibility gene method for Mycoplasma pneumoniae based on MALDI-TOF MS [PDF]
iScience, 2021 Summary: In this study, a multisite SNP genotyping and macrolide (ML) susceptibility gene test method for Mycoplasma pneumoniae (M. pneumoniae) was developed based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF
Fei Zhao +8 more
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Detecting SARS-CoV-2 variants with SNP genotyping. [PDF]
PLoS ONE, 2021 Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively ...
Helen Harper +11 more
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Research note: A low-density SNP genotyping panel for Chinese native chickens [PDF]
Poultry ScienceThe efficiency of molecular breeding largely depends on the cost of genotyping, which plays an important role in breeding and population genetic studies.
Jie Wang +10 more
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Development and Assessment of SNP Genotyping Arrays for Citrus and Its Close Relatives [PDF]
PlantsRapid advancements in technologies provide various tools to analyze fruit crop genomes to better understand genetic diversity and relationships and aid in breeding.
Yoko Hiraoka +4 more
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Unifying candidate gene and GWAS Approaches in Asthma. [PDF]
, 2010 The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Berg, Andrea von +21 more
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High‐Throughput SNP Genotyping [PDF]
ChemInform, 2002 AbstractWhole genome approaches using single nucleotide polymorphism (SNP) markers have the potential to transform complex disease genetics and expedite pharmacogenetics research. This has led to a requirement for high‐throughput SNP genotyping platforms. Development of a successful high‐throughput genotyping platform depends on coupling reliable assay
Suzanne Jenkins, Neil James Gibson
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