Results 1 to 10 of about 125,026 (143)

Development of an Assay to Distinguish Between Genotypes of the Leucyl-Cystinyl Aminopeptidase Gene

Re:GEN Open, 2022
Introduction: The leucyl-cystinyl aminopeptidase gene rs4869317 single nucleotide polymorphism (SNP) is associated with multiple conditions; for example, patients with the rs4869317 TT genotype experiencing septic shock have increased plasma clearance ...
Nayan J. Sarma, Shannon R. Dalton, Saji Vijayan   +2 more
doaj   +1 more source

Imputation strategies for genomic prediction using nanopore sequencing

BMC Biology, 2023
Background Genomic prediction describes the use of SNP genotypes to predict complex traits and has been widely applied in humans and agricultural species.
H. J. Lamb, L. T. Nguyen, J. P. Copley, B. N. Engle, B. J. Hayes, E. M. Ross   +5 more
doaj   +1 more source

Agrigenomic Diversity Unleashed: Current Single Nucleotide Polymorphism Genotyping Methods for the Agricultural Sciences

Applied Biosciences, 2023
Single Nucleotide Polymorphisms (SNPs) are variations that occur at single nucleotides in the genome and are present at an appreciable level in a population.
Roger D. Lawrie, Steven E. Massey
doaj   +1 more source

Genotyping by genome reducing and sequencing for outbred animals. [PDF]

PLoS ONE, 2013
Next-generation sequencing (NGS) approaches are widely used in genome-wide genetic marker discovery and genotyping. However, current NGS approaches are not easy to apply to general outbred populations (human and some major farm animals) for SNP ...
Qiang Chen, Yufang Ma, Yumei Yang, Zhenliang Chen, Rongrong Liao, Xiaoxian Xie, Zhen Wang, Pengfei He, Yingying Tu, Xiangzhe Zhang, Changsuo Yang, Hongjie Yang, Fuqing Yu, Youmin Zheng, Zhiwu Zhang, Qishan Wang, Yuchun Pan   +16 more
doaj   +1 more source

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

Malaria Journal, 2019
Background Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection.
Joseph Fulakeza, Sarah McNitt, Jimmy Vareta, Alex Saidi, Godfrey Mvula, Terrie Taylor, Don P. Mathanga, Dylan S. Small, Jacek Skarbinski, Julie R. Gutman, Karl Seydel   +10 more
doaj   +1 more source

Pooled DNA genotyping on Affymetrix SNP genotyping arrays

BMC Genomics, 2006
Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J, Moskvina Valentina, Georgieva Lyudmila, Nikolov Ivan, Kirov George, O'Donovan Michael C   +5 more
doaj   +1 more source

Development of STARP Marker Platform for Flexible SNP Genotyping in Sugarbeet

Agronomy, 2023
Single nucleotide polymorphisms (SNPs) have been widely used for gene identification. Allelic discrimination for an individual SNP with high reliability and flexibility is critical for the accurate detection of beneficial genes linked to specific SNP ...
Muhammad Massub Tehseen, Yaojie Zheng, Nathan A. Wyatt, Melvin D. Bolton, Shengming Yang, Steven S. Xu, Xuehui Li, Chenggen Chu   +7 more
doaj   +1 more source

A nanoliter fluidic platform for large-scale single nucleotide polymorphism genotyping

BioTechniques, 2009
Discovery, evaluation, and understanding the biological relevance of single nucleotide polymorphisms (SNPs) and their associated phenotypes is relevant to many applications, including human disease diagnostics, pathogen detection, and identification of ...
Douglas G. Roberts, Tom B. Morrison, Shau Neen Liu-Cordero, Jamie Cho, Javier Garcia, Tanya S. Kanigan, Kevin Munnelly, Colin J.H. Brenan   +7 more
doaj   +1 more source

Effect of Combining Multiple CNV Defining Algorithms on the Reliability of CNV Calls from SNP Genotyping Data [PDF]

Genomics & Informatics, 2012
In addition to single-nucleotide polymorphisms (SNP), copy number variation (CNV) is a major component of human genetic diversity. Among many whole-genome analysis platforms, SNP arrays have been commonly used for genomewide CNV discovery.
Soon-Young Kim, Ji-Hong Kim, Yeun-Jun Chung   +2 more
doaj   +1 more source

Temperature Switch PCR (TSP): Robust assay design for reliable amplification and genotyping of SNPs

BMC Genomics, 2009
Background Many research and diagnostic applications rely upon the assay of individual single nucleotide polymorphisms (SNPs). Thus, methods to improve the speed and efficiency for single-marker SNP genotyping are highly desirable.
Mather Diane E, Tabone Tania, Hayden Matthew J   +2 more
doaj   +1 more source