Results 31 to 40 of about 526,264 (266)
Genetic Variation in FADS Genes and Plasma Cholesterol Levels in 2-Year-Old Infants [PDF]
, 2013 Single nucleotide polymorphisms (SNPs) in genes involved in fatty acid metabolism (FADS1 FADS2 gene cluster) are associated with plasma lipid levels. We aimed to investigate whether these associations are already present early in life and compare the ...
Heinrich, Joachim +10 more
core +1 more source
Joint analysis of SNP and gene expression data in genetic association studies of complex diseases [PDF]
, 2014 Genetic association studies have been a popular approach for assessing the association between common Single Nucleotide Polymorphisms (SNPs) and complex diseases.
Huang, Yen-Tsung +2 more
core +1 more source
G × EBLUP: A novel method for exploring genotype by environment interactions and genomic prediction
Frontiers in Genetics, 2022 Genotype by environment (G × E) interaction is fundamental in the biology of complex traits and diseases. However, most of the existing methods for genomic prediction tend to ignore G × E interaction (GEI).
Hailiang Song +3 more
doaj +1 more source
Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. [PDF]
, 2015 Genome-wide association studies have identified over 70 single-nucleotide polymorphisms (SNPs) associated with breast cancer. A subset of these SNPs are associated with quantitative expression of nearby genes, but the functional effects of the majority ...
Brenner, Steven E +8 more
core +2 more sources
The Pan African Medical Journal, 2014 INTRODUCTION: Despite the medical progress in treatment. Tuberculosis (TB) continues to be a serious global health problem. A genome-wide linkage study identified a major susceptibility locus on chromosomal region 8q12-q13 in Moroccan TB patients.
Mounia Qrafli +10 more
doaj +1 more source
Single nucleotide polymorphisms from Theobroma cacao expressed sequence tags associated with witches' broom disease in cacao [PDF]
, 2009 In order to increase the efficiency of cacao tree resistance to witches¿ broom disease, which is caused by Moniliophthora perniciosa (Tricholomataceae), we looked for molecular markers that could help in the selection of resistant cacao genotypes.
Carels, Nicolas +10 more
core +1 more source
SNPsyn: detection and exploration of SNP–SNP interactions [PDF]
Nucleic Acids Research, 2011 SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic approach called interaction analysis.
Curk, Tomaz, Rot, Gregor, Zupan, Blaz
openaire +3 more sources
Accurate Genomic Prediction Of Human Height [PDF]
, 2017 We construct genomic predictors for heritable and extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning).
Avery, Steven G. +5 more
core +1 more source
Italian Journal of Animal Science, 2021 In this study, we conducted a genome-wide association study (GWAS) for five milk production traits in the Valle del Belice sheep. Repeated measurements for milk yield (MY), fat percentage and yield (F% and FY) and protein percentage and yield (P% and PY)
Anna Maria Sutera +6 more
doaj +1 more source
Genetic variants in ELOVL2 and HSD17B12 predict melanoma‐specific survival [PDF]
, 2019 Fatty acids play a key role in cellular bioenergetics, membrane biosynthesis and intracellular signaling processes and thus may be involved in cancer development and progression.
Amos, Christopher I. +12 more
core +1 more source