Results 61 to 70 of about 526,264 (266)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The association of vascular endothelial growth factor related SNPs and circulating iron levels might depend on body mass index

Frontiers in Bioscience-Landmark, 2022
Background and objectives: Vascular Endothelial Growth Factor (VEGF) is an essential regulator of vascular biology. In addition to the well-established role in angiogenesis, circulating VEGF levels were found elevated in severely anemic patients ...
Pia Chedid, Ali Salami, Mariam Ibrahim, Sophie Visvikis-Siest, Said El Shamieh   +4 more
doaj   +1 more source

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in Cypriot population. [PDF]

, 2010
Inability to correctly repair DNA damage is known to play a role in the development of breast cancer. Single nucleotide polymorphisms (SNPs) of DNA repair genes have been identified, which modify the DNA repair capacity, which in turn may affect the risk
Bashiardes, E, Cariolou, MA, Daniel, M, Hadjisavvas, A, Kakouri, E, Loizidou, MA, Marcou, Y, Michael, T, Neuhausen, SL, Newbold, RF   +9 more
core  

Population genomics of the Asian tiger mosquito, Aedes albopictus. Insights into the recent worldwide invasion [PDF]

, 2017
Aedes albopictus, the “Asian tiger mosquito,” is an aggressive biting mosquito native to Asia that has colonized all continents except Antarctica during the last ~30–40 years. The species is of great public health
Aguirre-Obando, Alexander, Armbruster, Baird, Becker, Beebe, Benedict, Birungi, Bonizzoni, Brady, Brown, Chen, Chen, Chouin-Carneiro, Dalla Pozza, Damal, Danecek, Das, Delatte, Denlinger, Eaton, Egizi, Emerson, Excoffier, Flacio, Foll, Frichot, Galtier, Gloria-Soria, Goubert, Gratz, Hawley, Hemingway, Hurst, Ismail, Jackson, Jombart, Kambhampati, Kambhampati, Kamgang, Kamgang, Kasai, Lamballerie, Lambrechts, Langmead, Lewis, Li, Lischer, Liu, Lounibos, Lounibos, Lourenco de Oliveira, Luu, Manni, Manni, Marcombe, Maynard, Medley, Medlock, Minard, Morens, Mori, Mousson, Nazareno, O'Donnell, Patterson, Paupy, Pech-May, Peterson, Porretta, Porretta, Powell, Puckett, Reiter, Smartt, Sprenger, Stamatakis, Tatem, Trucchi, Urbanelli, Urbanski, Willing, Wong, Wray, Wu, Xu, Zhong   +86 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A High-Density Genetic Map for Cucumber (Cucumis Sativus L.) Based on Specific Length Amplified Fragment (SLAF) Sequencing and QTL Analysis of Fruit Traits in Cucumber

Frontiers in Plant Science, 2016
High-density genetic linkage map plays an important role in genome assembly and QTL fine mapping. Since the coming of next-generation sequencing (NGS), makes the structure of high-density linkage maps much more convenient and practical, which simplifies ...
Wenying eZhu, Long eHuang, Long eChen, Jiantao eYang, Jiani eWu, Meiling eQu, Danqing eYao, Chunli eGuo, Hongli eLian, Huanle eHe, Junsong ePan, Run eCai   +11 more
doaj   +1 more source

Pest Management Challenges and Control Practices in Codling Moth: A Review

Insects, 2020
The codling moth, Cydia pomonella L., is a serious insect pest in pome fruit production worldwide with a preference for apple. The pest is known for having developed resistance to several chemical groups of insecticides, making its control difficult. The
Martina Kadoić Balaško, Renata Bažok, Katarina M. Mikac, Darija Lemic, Ivana Pajač Živković   +4 more
doaj   +1 more source

Electrochemical SNP detection [PDF]

Nucleic Acids Symposium Series, 2006
Detection of mismatched base on a DNA duplex, which is important for the search of the heterozygote, achieved by the comparison with the reactivity of ferrocenylcarbodiimide (1) developed by our group. Mismatched thymine base on the 30-meric DNA duplex as a model of SNPs in lipoprotein lipase (LPL) gene, could react with 1 in 20 mM borate buffer (pH 8 ...
Sadayoshi, Watanabe, Kosuke, Mukumoto, Takahiko, Nojima, Michinori, Waki, Shigeori, Takenaka   +4 more
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes. [PDF]

, 2012
Aims/hypothesisWhile genome-wide association studies (GWASs) have been successful in identifying novel variants associated with various diseases, it has been much more difficult to determine the biological mechanisms underlying these associations ...
Butte, AJ, Chen, R, Corona, E, Kang, HP, Schadt, EE, Yang, X, Zhang, B   +6 more
core   +2 more sources