Results 111 to 120 of about 27,950,601 (288)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Influencer marketing meets consumer protection : the role of the rules on unfair commercial practices in regulating social media influencers

This chapter examines the extent to which social media influencers are subject to the rules on unfair commercial practices when they promote third-party traders’ products to their followers.
Kerckaert, JulieRE210001409642388020035495290009-0006-9000-22464C71A69E-3DED-11E4-8AC5-DAE6B4D1D7B1, Geiregat, SimoneditorRE210001000520628020017834220000-0002-5614-18792811D466-F0EE-11E1-A9DE-61C894A0A6B4, Kerckaert, JulieeditorRE210001409642388020035495290009-0006-9000-22464C71A69E-3DED-11E4-8AC5-DAE6B4D1D7B1   +2 more
core  

Social media influencers and followers’ loneliness: the mediating roles of parasocial relationship, sense of belonging, and social support

Online Media and Global Communication
Prior research examines how social media use in general affects experiences of loneliness, but few studies have investigated the specific effects of interaction with social media influencers on loneliness and well-being.
Liu Juan, Lee Jung-Sook
doaj   +1 more source

Instagram influencers attributes and parasocial relationship: A dataset from Qatar

Data in Brief
The dataset investigates how social media influencers’ attributes affect followers’ parasocial relationship. It also examines the mediating role of the parasocial relationship between the social media influencers’ attributes and behavioral intentions.
Sara Al Sulaiti, Mohamed Slim Ben Mimoun, Hatem Elgohary   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Orthodontists on Social Media: Instagram’s Influence

Turkish Journal of Orthodontics
The aim of this study was to determine how orthodontists utilize the social media application Instagram for health communication.Four Turkish keywords were manually searched on the Instagram platform on February 12, 2022: "orthodontist" (ortodontist), "orthodontics" (ortodonti), "orthodontic specialist" (ortodonti uzmanı), and "doctor of orthodontist" (
Mehmet Ali Yavan, Gökçenur Gökçe
openaire   +3 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Educationalinfluencers Romanian youths live by: an analysis of how religion is shared through social media [PDF]

Diversitate si Identitate Culturala in Europa
Romanian celebrities on social media (influencers) have begun to exert persuasion on a massive scale, potentially influencing the young people who follow them while pursuing individual profit. This study sets out to investigate the content shared by such
Silvia FLOREA
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Entrepreneurs of Social Media : How Social Media Influencers differ from other Social Media Users

, 2019
Background:  Over the years, traditional entrepreneurs started businesses due to either pull or push factors within their environments. Research has been carried out in profiling different types of entrepreneurs and their characteristics.
Adenola, Janet Temitope
core   +2 more sources