Results 101 to 110 of about 663,468 (311)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Information propagation analysis in a social network site

open access: yes, 2010
One of the most interesting and still not completely understood phenomena happening in Social Network Sites is their ability to spread (or not) units of information which may aggregate to form large distributed conversations. In this paper we present the
Danilo Montesi   +6 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Social positions and simulation relations

open access: yes, 2011
Describing social positions and roles is an important topic within the social network analysis. Identifying social positions can be difficult when the target organization lacks a formal structure or is partially hidden.
Brynielsson, Joel,   +5 more
core   +1 more source

Network analysis of international export pattern

open access: yes, 2022
There is a relationship between the trade flows of the countries and their economic growth potential and development. One way to analyze the trade flows of countries with each other is the use of network analysis techniques.
İnce-Yenilmez, Meltem   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis and Control of Beliefs in Social Networks

open access: yesIEEE Transactions on Signal Processing, 2014
In this paper, we investigate the problem of how beliefs diffuse among members of social networks. We propose an information flow model (IFM) of belief that captures how interactions among members affect the diffusion and eventual convergence of a belief.
Tian Wang, Hamid Krim, Yannis Viniotis
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The impact of changing personal relationship dynamics on quality of life throughout the UK COVID-19 lockdowns – a mixed methods study

open access: yesConnections
The COVID-19 pandemic resulted in multiple UK-wide lockdowns, which prevented individuals from meeting friends and family outside their confined households.
Shepherd Ryan J.   +2 more
doaj   +1 more source

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