Results 91 to 100 of about 663,468 (311)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Topics in social network analysis and network science
CoRR, 2014 This chapter introduces statistical methods used in the analysis of social networks and in the rapidly evolving parallel-field of network science. Although several instances of social network analysis in health services research have appeared recently, the majority involve only the most basic methods and thus scratch the surface of what might be ...
A. James O'Malley, Jukka-Pekka Onnela
openaire +2 more sources
Using social network analysis to enhance information retrieval systems
, 2008 It is an ongoing trend that people increasingly reveal very personal information on social network sites in particular and in the World Wide Web in general.
Nicolai, Thomas +3 more
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The one comparing narrative social network extraction techniques [PDF]
, 2020 Analysing narratives through their social networks is an expanding field in quantitative literary studies. Manually extracting a social network from any narrative can be time consuming, so automatic extraction methods of varying complexity have been ...
Roughan, M. +3 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Social Network Analysis: Literature Review
Online Academic Journal of Information Technology, 2018 In this article, social network analysis SNA is defined and historical development process is explained. A comprehensive literature search has been conducted for this purpose. SAA is a powerful method that centralizes individuals and their relations,
Nursen Aydın
doaj +1 more source
An evaluation of technological districts through a network approach
, 2011 The aim of the paper is to give a theoretical and applied framework for analyzing the efficacy of public grants to joint R&D projects realized by firms.
CAPUANO, CARLO
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Command and control in emergency services operations: A social network analysis
, 2006 There is increasing interest in the use of social network analysis as a tool to study the performance of teams and organizations. In this paper, processes of command and control in the emergency services are explored from the perspective of social ...
McMaster, Richard +23 more
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