Results 111 to 120 of about 2,948,492 (314)
Tourism Destinations Network Analysis, Social Network Analysis Approach
مدیریت تولید و عملیات, 2015 The tourism industry is becoming one of the world's largest economical sources, and is expected to become the world's first industry by 2020. Previous studies have focused on several aspects of this industry including sociology, geography, tourism ...
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doaj
Computers in Human Behavior ReportsIn today’s age of digital interconnectedness, understanding and addressing the nuances of social cybersecurity have become paramount. Unlike its broader counterparts, information security and cybersecurity, which are focused on safeguarding all forms of ...
Aos Mulahuwaish +7 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Information exchange in construction design phase: a case study using Social Network Analysis
, 2021 Bao Ngoc Nguyen
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Network Topology Optimization Using Social Network Analysis
Journal of Engineering and Sustainable Development, 2006 The topological design of networks in this work consists of finding a topology (directed and undirected links flow) that improve both the reliability index and increase the available shortest paths in the network without overloading the routing table or
Siddeeq Y. Ameen, Alaa N. Al-Qeicy
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Study on the Evolution of Industrial Network Structure Characteristics in Xinjiang Based on Social Network Analysis Method [PDF]
星宏 陈
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