Results 101 to 110 of about 654,954 (312)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The measurement of training opportunities course outcomes: an effective policy tool?
, 2004 Training Opportunities is an active labour market policy initiative, and part of a response to the entrenched problems of unemployment in Aotearoa New Zealand.
Stolte, Ottilie Emma Elisabeth
core
International Journal of Health Geographics, 2004 Background There is evidence of a contribution of early life socioeconomic exposures to the risk of chronic diseases in adulthood. However, extant studies investigating the impact of the neighborhood social environment on health tend to characterize only
Whitsel Eric A +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Journal of Clinical and Translational Science, 2018 IntroductionThe Best Practices in Social and Behavioral Research Course was developed to provide instruction on good clinical practice for social and behavioral trials.
Susan L. Murphy +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A BRIEF DISCUSSION ON SOCIAL WORK ETHICS EDUCATION
, 2018 Journal of Academic Perspective on Social StudiesJournal of Academic Perspective on Social StudiesEthics hasbecome a crucial evaluation criterion in various sciences as well as socialwork in recent years.
Demet AKARÇAY ULUTAŞ
core +1 more source
Social inequalities in educational attainment. The changing impact of parents’ social class, social status, education, and family: England 1986 and 2010 [PDF]
, 2019 There is controversy regarding trends over time in the association between social origins and educational outcomes in the UK. An explanation may lie in different methods of analysis.
Pensiero, Nicola +5 more
core +1 more source
The Adventure of Geography in Social Studies: A Study on Change
Anadolu Üniversitesi Eğitim Fakültesi dergisi, 2022 Geography is one of the important building blocks of the social studies course. For this reason, it is necessary to follow the geography discipline, to renew it with up-to-date information, and to ensure its sustainability in the content of the social ...
B. Ünal İbret, Onur Yılmaz
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source