Results 131 to 140 of about 654,954 (312)

Social class differences in early cognitive development: a response from Leon Feinstein

, 2015
Leon Feinstein gives his response to commentaries on his opening paper in the debate Social class differences in early cognitive development, published in the previous edition of this ...
Feinstein, Leon
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Analysis of 4th and 5th Graders’ Perceptions of Social Studies

Kuramsal Eğitimbilim Dergisi, 2012
Education firstly begins in family, and continues with formal education as a fact which should be continued through life. But, the basic foundations of education need to be taken into consideration to be efficient.
Barış ÇİFTÇİ , Mehmet Tamer KAYA
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Concept learning and reasoning in social studies education (COURSE) [Elektronisk resurs] : Session 160: How do values transform when history culture change?

, 2021
How do values transform when history culture change? In addition, is it possible to discern such a development in an ongoing classroom student-teacher discourse? In this presentation, I try to address these questions through two intertwined issues: first
Olofsson, Hans,, Maliks, Jakob,, Kvande, Lise,   +2 more
core  

Comparison Of 2005 Social Studies Course Curriculum And 2017 Social Studies Course Draft Curriculum

, 2017
Bu araştırmada, 2005 sosyal bilgiler dersi öğretim programı ile 2017 yılı sosyal bilgiler dersi taslak öğretim programının karşılaştırılması amaçlanmıştır. Bu araştırma, nitel araştırma modellerinden durum çalışması niteliğindedir. Araştırma verilerinin kaynağını Milli Eğitim Bakanlığının yayımlamış olduğu 2005 sosyal bilgiler dersi öğretim programı ...
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

THE EFFECTS OF THEMATIC SOCIAL STUDIES INSTRUCTION ON EIGHTH GRADE STUDENTS’ HISTORICAL REASONING ABILITY AND ATTITUDES TOWARDS SOCIAL STUDIES RELATED TASKS

, 2013
This study examined the potential benefits of thematic-based social studies instruction on middle school students’ historical reasoning ability and attitudes towards social studies related tasks.
Cloutier, Andrew
core