Results 221 to 230 of about 123,422 (307)

Analysis of the association between dietary sodium intake and cognitive function: a NHANES-based machine learning study and animal experimental validation. [PDF]

Front Nutr
Wang S, Deng K, Zhao H, Wang Y, Guo P, Jin H, Qi L.   +6 more
europepmc   +1 more source

Vascular Endothelial NAMPT‐Mediated NAD+ Biosynthesis Regulates Angiogenesis and Cardiometabolic Functions in Male Mice

Aging Cell, EarlyView.
Using male vascular endothelial cell–specific Nampt knockout and naturally aged mice, we identified endothelial NAD+ deficiency as a central driver of age‐related angiogenic failure, impaired subcutaneous adipogenesis, and cardiometabolic dysfunction.
Shotaro Kosugi, Shintaro Yamaguchi, Ken Nishioka, Taichi Nagahisa, Yasuhiro Watanabe, Daiki Kojima, Kenji Kaneko, Ryunosuke Mitsuno, Ran Nakamichi, Yoshinaga Kawano, Kenichiro Kinouchi, Koichiro Homma, Takeshi Kanda, Junichiro Irie, Kazutoshi Miyashita, Toshiaki Monkawa, Jun Yoshino, Hiroshi Itoh, Kaori Hayashi   +18 more
wiley   +1 more source

Utilizing brown mushroom stem waste as an eco-friendly alternative to soybean meal in layer chick nutrition. [PDF]

Front Vet Sci
Abdel-Wareth AAA, Stamps KG, Salahuddin M, Balan V, Mohammadi M, Kim WK, Zhu W, Ahmed AA, Gray CD, Aviña AMW, Rounds-Carter T, Carr T, Williams A, Bakare A, Lohakare J.   +14 more
europepmc   +1 more source

Brain DNA Methylation Atlas of AppNL‐G‐F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline‐Induced Resilience

Aging Cell, EarlyView.
Brain DNA methylation drives abnormal gene expression in AppNL‐G‐F mice. Perinatal choline supplementation may promote resilience to synaptic dysfunction through modulation of DNA methylation. ABSTRACT Alzheimer's disease (AD) is the most common type of dementia.
Andre Krunic, Thomas A. Bellio, Benjamin Z. Cohen, Adam Labadorf, Thor D. Stein, Honghuang Lin, Tiffany J. Mellott, Jan K. Blusztajn   +7 more
wiley   +1 more source

Utilizing white mushroom stem powder as a sustainable substitute for soybean meal in layer chick diets. [PDF]

Poult Sci
Stamps KG, Abdel-Wareth AAA, Salahuddin M, Balan V, Mohammadi M, Kim WK, Zhu W, Ahmed AA, Rounds-Carter T, Gray CD, Aviña AMW, Carr T, Williams A, Bakare A, Lohakare J.   +14 more
europepmc   +1 more source

Canagliflozin Reprograms the Aging Hippocampus in Genetically Diverse UM‐HET3 Mice and Attenuates Alzheimer's‐Like Pathology

Aging Cell, EarlyView.
Canagliflozin enhances hippocampal function, reduces Aβ pathology, and improves cognitive function in male mice, while females show limited benefits, revealing sex‐specific neuroprotective responses across aging and Alzheimer's models. ABSTRACT Aging is the strongest risk factor for cognitive decline and Alzheimer's disease (AD), yet the mechanisms ...
Hashan Jayarathne, Dulmalika Herath Manchanayake, Ryan Sullivan, Nina Chimienti, Omar Kadri, Katherine Gurdziel, Seongho Kim, Hyejeong Jang, Brett C. Ginsburg, Richard A. Miller, Shoshana Yakar, Marianna Sadagurski   +11 more
wiley   +1 more source

Effect of sodium-reduced potassium-enriched salt substitutes on stomach cancer: the Salt Substitute and Stroke Study (SSaSS). [PDF]

BMC Med
Zhang X, Yin X, Yap ML, Li Q, Huang L, Liu Y, Zhou B, Li Z, Zhao Y, Sun J, Yu Y, Yan LL, Wu Y, Neal B, Tian M.   +14 more
europepmc   +1 more source

The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone

Aging Cell, EarlyView.
scRNA‐seq analysis reveals age‐related changes in bone mesenchymal cells in male and female mice. Moreover, the comparison of aging and autophagy deficiency in bone mesenchymal cells shows overlap and suggests that age‐related decline in autophagy contributes to skeletal aging.
Melda Onal, Intawat Nookaew, Ana Resende‐Coelho, Olivia Reyes‐Castro, Adriana Marques‐Carvalho, Landon Gatrell, Alongkorn Kurilung, Alicen James, Aaron Warren, Ha‐Neui Kim, Jinhu Xiong, Charles A. O'Brien, Maria Almeida   +12 more
wiley   +1 more source

Dietary and environmental modulation for the gut environment: yogurt promotes microbial diversity while chloride hot springs improve defecation status in healthy adults. [PDF]

Front Nutr
Choi J, Takeda M, Managi S.
europepmc   +1 more source

Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Academic Emergency Medicine, EarlyView.
ABSTRACT Study Objective Treatment strategies in severe hyponatremia aim at rapid sodium correction to prevent or treat cerebral edema but limit sodium rise to prevent osmotic demyelination syndrome (ODS). The true risk of edema or ODS in ED patients is unknown.
Volker Burst, Ramon Rabii, Julian Peto‐Madew, Thorsten Persigehl, Stefan Haneder, Matthias Johannes Hackl, Christoph Hüser, Moritz Trappe, Sadrija Cukoski, Kathrin Möllenhoff, Victor Suárez   +10 more
wiley   +1 more source