Results 21 to 30 of about 128,651 (308)
Frontiers in Cell and Developmental Biology, 2020 ASCT2 is a neutral amino acid transporter, which catalyzes a sodium-dependent obligatory antiport among glutamine and other neutral amino acids. The human ASCT2 over-expressed in Pichia pastoris and reconstituted in proteoliposomes has been employed for ...
Mariafrancesca Scalise +7 more
doaj +1 more source
EAAT1-dependent Transcriptional Control depends on the Substrate Translocation Process
ASN Neuro, 2022 Glutamate, the major excitatory neurotransmitter in the vertebrate brain, is removed from the synaptic cleft by a family of sodium-dependent transporters expressed in neurons and glial cells.
Dinorah Hernández-Melchor +5 more
doaj +1 more source
Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium. [PDF]
PLoS ONE, 2012 Glutamate-induced cytotoxicity is partially mediated by enhanced oxidative stress. The objectives of the present study are to determine the effects of glutamate on mitochondrial membrane potential, oxygen consumption, mitochondrial dynamics and autophagy
Santosh Kumari +2 more
doaj +1 more source
Glutamic acid and its Sodium salt Glutamate(Aji-no-moto)
Anusandhaan - Vigyaan Shodh Patrika, 2018 Glutamic acid is an alpha amino acid that is used by almost all living beings. It is non–essential acidic amino acid. MSG (Mono Sodium Glutamate) is a food additive. MSG is a flavour enhancer. It is traded under the name Aji–no–moto. MSG elicits a unique taste known as UMAMI as a 5th basic taste different from the other basic tastes(bitter, salty, sour,
Devendra Kumar, Sakshi Gupta
openaire +2 more sources
Are foods naturally rich in glutamic acid an alternative to sodium reduction? [PDF]
Food Science and Technology, 2020 Abstract Chronic non-communicable diseases (NCDs) prevalence has been growing, hence the importance of studying food alternatives with reduced sodium content sensory well accepted. Develop culinary preparations reduced in sodium, with addition of glutamic acid-rich ingredients, and evaluate their sensory acceptance.
Fernanda Ferreira dos SANTOS +4 more
openaire +5 more sources
Molecules, 2023 In this study, an electrochemical sensor was developed by immobilizing colon cancer and the adjacent tissues (peripheral healthy tissues on both sides of the tumor) and was used to investigate the receptor sensing kinetics of glucose, sodium glutamate ...
Dingqiang Lu +7 more
doaj +1 more source
Проблеми екології та медицини, 2023 Over the past century, since the rapid development of mankind as a civilization, the state of the environment and the conditions of everyday human existence have undergone significant changes.
O.V. Mamai, S.M. Bilash, R.M. Grinko
doaj +1 more source
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli +15 more
wiley +1 more source
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels
Cell Reports, 2021 Summary: Vesicular glutamate transporters (VGLUTs) fill synaptic vesicles with glutamate. VGLUTs were originally identified as sodium-dependent transporters of inorganic phosphate (Pi), but the physiological relevance of this activity remains unclear ...
Cyril Cheret +4 more
doaj
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source