Results 21 to 30 of about 11,077 (217)

Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies [PDF]

open access: yes, 2015
By reducing energy density, low-energy sweeteners (LES) might be expected to reduce energy intake (EI) and body weight (BW). To assess the totality of the evidence testing the null hypothesis that LES exposure (versus sugars or unsweetened alternatives ...
de Graaf, C   +10 more
core   +5 more sources

Drinking Water with Saccharin Sodium Alters the Microbiota-Gut-Hypothalamus Axis in Guinea Pig

open access: yesAnimals, 2021
The effects of saccharin, as a type of sweetener additive, on the metabolism and development of mammals are still controversial. Our previous research revealed that saccharin sodium (SS) promoted the feed intake and growth of guinea pigs.
Junrong Li   +9 more
doaj   +1 more source

Bitter taste stimuli induce differential neural codes in mouse brain. [PDF]

open access: yes, 2012
A growing literature suggests taste stimuli commonly classified as "bitter" induce heterogeneous neural and perceptual responses. Here, the central processing of bitter stimuli was studied in mice with genetically controlled bitter taste profiles.
Boughter, John D   +2 more
core   +2 more sources

APLICAÇÃO DA ESPECTROSCOPIA NO INFRAVERMELHO E DIFRAÇÃO DE RAIO-X NA DETERMINAÇÃO DE SACARINA EM ADOÇANTES LÍQUIDOS ARTIFICIAIS PELO MÉTODO VOLUMÉTRICO COM AG+

open access: yesEclética Química, 2018
The use of sweeteners liquid from saccharin sodium is a public health issue by the relationship with obesity and a source of sodium. The  levels of saccharin were studied in four different manufacturers in samples from trade in Vitória / ES, between ...
Jhonatas de Souza Lima   +2 more
doaj   +1 more source

Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]

open access: yes, 2019
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran   +14 more
core   +1 more source

Effect of food additives on key bacterial taxa and the mucosa-associated microbiota in Crohn’s disease. The ENIGMA study

open access: yesGut Microbes, 2023
Food additives have been linked to the pro-inflammatory microbial dysbiosis associated with Crohn’s disease (CD) but the underlying ecological dynamics are unknown.
J.J. Jimenez Loayza   +18 more
doaj   +1 more source

Effects of non‐caloric artificial sweeteners on naïve and dextran sodium sulfate‐exposed Drosophila melanogaster

open access: yesFood Frontiers, 2022
Saccharin and sucralose are worldwide used tabletop non‐caloric artificial sweeteners (NAS), and although they are considered metabolically inert and safe for consumption, recent studies observed an NAS‐mediated modulation of the intestinal microbiota ...
Inga Hubrecht   +3 more
doaj   +1 more source

Comparison of Studies on Saccharin and Sodium Nitrite

open access: yesJournal of AOAC INTERNATIONAL, 1979
Abstract A review of long term animal studies of saccharin and sodium nitrite was undertaken to assess the effect of variability of selected protocol elements on the results obtained. These elements were divided into 4 general categories: design, including selection of test animals, basal diet, dosage form and doses of test substance ...
J M, Taylor, V H, Morgenroth
openaire   +2 more sources

Evaluation of Cytotoxicity and Taste-Masking Effect of Selected Flavors on Dental Lidocaine HCl Injection

open access: yesPharmaceuticals, 2020
Aim: Anxiety and intolerance to dental local anesthetic injections are common in patients undergoing dental procedures. This work was designed to study cytotoxicity of selected flavors in primary gingival keratinocytes (PGK), to acquire information on ...
Sai H. S. Boddu   +7 more
doaj   +1 more source

Corticosterone Regulates Both Naturally Occurring and Cocaine‐Induced Dopamine Signaling by Selectively Decreasing Dopamine Uptake [PDF]

open access: yes, 2017
Stressful and aversive events promote maladaptive reward‐seeking behaviors such as drug addiction by acting, in part, on the mesolimbic dopamine system. Using animal models, data from our laboratory and others show that stress and cocaine can interact to
Baker, David A.   +9 more
core   +2 more sources

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