Results 51 to 60 of about 1,194,614 (343)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Soft Error in Saddle Fin-Based DRAM at Cryogenic Temperature

IEEE Access
This study examines the impact of soft error by heavy ions on saddle fin-based dynamic random access memory (DRAM). The investigation is conducted using technology computer-aided design (TCAD) simulation at different temperatures ranging from 77 to 300 K.
Minsang Ryu, Minki Suh, Jonghyeon Ha, Minji Bang, Dabok Lee, Hojoon Lee, Hyunchul Sagong, Dong-Seok Kim, Jungsik Kim   +8 more
doaj   +1 more source

Survey of Soft Error Mitigation Techniques Applied to LEON3 Soft Processors on SRAM-Based FPGAs

IEEE Access, 2020
Soft-core processors implemented in SRAM-based FPGAs are an attractive option for applications to be employed in radiation environments due to their flexibility, relatively-low application development costs, and reconfigurability features enabling them ...
Server Kasap, Eduardo Weber Wachter, Xiaojun Zhai, Shoaib Ehsan, Klaus Mcdonald-Maier   +4 more
doaj   +1 more source

Exploiting Data Representation for Fault Tolerance [PDF]

, 2013
We explore the link between data representation and soft errors in dot products. We present an analytic model for the absolute error introduced should a soft error corrupt a bit in an IEEE-754 floating-point number.
Elliott, James, Hoemmen, Mark, Mueller, Frank   +2 more
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Double-Node-Upset Fully-Tolerant/Recoverable and Triple-Node-Upset Partially-Tolerant Self-Recoverable Latch Design for Aerospace Applications

IEEE Access
Due to the continuous scaling down of transistor size in integrated circuits, sensitive nodes are becoming increasingly vulnerable to node upset, especially in aerospace, because of their high radiation environment.
Urmila Saha, Bayartulga Ishdorj, Jaeyong Jang, Taehui Na   +3 more
doaj   +1 more source

Nonlinear voltage error analysis and control of resonant high precision converter

Energy Reports, 2023
The current nonlinear distortion of power converter can cause motion trajectory error and positioning error of motor, and affect the nano motion and positioning accuracy of ultra-precision system.
Jian Wei, Jiawei Zhang, Baoquan Kou, Lu Zhang, Hailin Zhang   +4 more
doaj   +1 more source

Soft Error Characterization on Scientific Applications

2018 IEEE 16th Intl Conf on Dependable, Autonomic and Secure Computing, 16th Intl Conf on Pervasive Intelligence and Computing, 4th Intl Conf on Big Data Intelligence and Computing and Cyber Science and Technology Congress(DASC/PiCom/DataCom/CyberSciTech), 2018
Decreasing transistor sizes, aggressive power optimization techniques and higher operation frequencies lead to increase error rates. While researchers addressed reliable computing, there is still lack of study for providing the fundamental understanding of error propagation. In this work, we characterize error propagation at software level by utilizing
Ozturk, Zuhal, Topcuoglu, Haluk Rahmi, Arslan, Sanem, Kandemir, Mahmut Taylan   +3 more
openaire   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

The Impact of Positional Errors on Soft Classification Accuracy Assessment: A Simulation Analysis

Remote Sensing, 2015
Validating or accessing the accuracy of soft classification maps has rapidly developed over the past few years. This assessment employs a soft error matrix as generalized from the traditional, hard classification error matrix.
Jianyu Gu, Russell G. Congalton, Yaozhong Pan   +2 more
doaj   +1 more source