A Platform-Based Software Design Methodology for Embedded Control Systems: An Agile Toolkit [PDF]
A discrete control system, with stringent hardware constraints, is effectively an embedded real-time system and hence requires a rigorous methodology to develop the software involved.
Carlos Mar +14 more
core +1 more source
Research on garment pattern design based on fractal graphics
This paper firstly analyzes the basic principle of generating fractal art graphics and the artistic features of graphics and then uses scientific visualization method to innovate and improve the theoretical model used in this paper.
Weijie Wang +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Defect patterns and structural properties in a mature well-specified software system [PDF]
Software engineering is not an empirically based discipline. As a result, many of its practices are based on little more than a generally agreed feeling that something may be true.
Hopkins, Tim, Hatton, Leslie
core
Agile Development Methodology for Embedded Systems: A Platform-Based Design Approach
This paper describes an agile development methodology which combines agile principles with organizational patterns and adapts them to build embedded real-time systems focusing on the system's constraints.
Cordeiro, Lucas +12 more
core +1 more source
Automatic detection of software design patterns using a language model on transformer architecture
This article addresses the significance of Gang of Four (GoF) design patterns as formal architectural solutions in objectoriented programming and emphasizes the importance of their automated detection in modern software systems.
J. Asaad, E. Yu. Аvksentieva
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Investigating the Use of Object-Oriented Design Patterns in Open-Source Software: A Case Study
During the last decade open source software communities are thriving. Nowadays, several open source projects are so popular that are considered as a standard in their domain. Additionally, the amount of source code that is freely available to developers,
Loucopoulos, Pericles +4 more
core +1 more source
Hierarchical Patterns: A Way to Organize (Analysis) Patterns [PDF]
The paper addresses the issue of categorization and generalization in software patterns. It focuses on the realm of analysis (conceptual) patterns in which the problem is more noticeable when compared to design patterns. The paper introduces hierarchical
Lubor Sesera
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

