Results 61 to 70 of about 876,988 (310)

An Overview of Design Patterns for Self-Adaptive Systems in the Context of the Internet of Things

open access: yesIEEE Access, 2020
The Internet of Things (IoT) requires the integration of all available, highly specialized, and heterogeneous devices, ranging from embedded sensor nodes to servers in the cloud.
Christian Krupitzer   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Design Pattern Detection by Using Meta Patterns [PDF]

open access: yes, 2008
One of the approaches to improve program understanding is to extract what kinds of design pattern are used in existing object-oriented software. This paper proposes a technique for efficiently and accurately detecting occurrences of design patterns ...
KOBAYASHI, Takashi   +4 more
core  

Designing and Implementing Software Systems using User-defined Design Patterns

open access: yes, 2021
Software design patterns are the design-level solutions for the commonly occurring problems in software development. Design patterns are applied in many industries where problems repeat with slight changes, and applying the same solution that is proven ...
Mehmet Kose   +3 more
core   +1 more source

Architecture-centric software evolution by software metrics and design patterns [PDF]

open access: yesProceedings of the Sixth European Conference on Software Maintenance and Reengineering, 2003
It is shown how software metrics and architectural patterns can be used for the management of software evolution. In the presented architecture-centric software evolution method the quality of a software system is assured in the software design phase by computing various kinds of design metrics from the system architecture, by automatically exploring ...
Juha Gustafsson   +3 more
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Design patterns for wildlife‐related camera trap image analysis

open access: yesEcology and Evolution, 2019
This paper describes and explains design patterns for software that supports how analysts can efficiently inspect and classify camera trap images for wildlife‐related ecological attributes.
Saul Greenberg   +2 more
doaj   +1 more source

Design pattern mining using distributed learning automata and DNA sequence alignment. [PDF]

open access: yesPLoS ONE, 2014
CONTEXT: Over the last decade, design patterns have been used extensively to generate reusable solutions to frequently encountered problems in software engineering and object oriented programming. A design pattern is a repeatable software design solution
Mansour Esmaeilpour   +2 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

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