Results 71 to 80 of about 14,948,240 (284)
Combining Structural Features and Software Metrics for Automated Design Pattern Detection
IEEE AccessDesign patterns provide reusable solutions to recurring software design problems. Since their introduction by the Gang of Four in 1994, identifying these patterns in object-oriented programs has remained a challenging task, particularly with regard to ...
Mohammed Ghazi Al-Obeidallah
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Design patterns for wildlife‐related camera trap image analysis
Ecology and Evolution, 2019 This paper describes and explains design patterns for software that supports how analysts can efficiently inspect and classify camera trap images for wildlife‐related ecological attributes.
Saul Greenberg +2 more
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Software patterns to improve knowledge transfer: an experiment. [PDF]
Patterns for software development have been a hot topic for some time within the object-oriented community. Patterns are part of a software engineering problem-solving discipline. It all started with Design Patterns [11], but gradually patterns were used
De Rore, Lotte +3 more
core
Implementation Support of Security Design Patterns Using Test Templates
Information, 2016 Security patterns are intended to support software developers as the patterns encapsulate security expert knowledge. However, these patterns may be inappropriately applied because most developers are not security experts, leading to threats and ...
Masatoshi Yoshizawa +5 more
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Pattern-Oriented Reengineering of a Network System [PDF]
Journal of Systemics, Cybernetics and Informatics, 2004 Reengineering is to reorganize and modify existing systems to enhance them or to make them more maintainable. Reengineering is usually necessary as systems evolve due to changes in requirements, technologies, and/or personnel.
Chung-Horng Lung, Qiang Zhao
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Colloquium Exactarum, 2016 - Design patterns are applied to reuse standardized software solutions to solve common problems. However, there is still an obstacle: the difficulty in learning about design pattern and the lack of knowledge of the involved designers.
Caroline Teixeira da Cruz +2 more
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