Results 71 to 80 of about 676,694 (342)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Requirements engineering: a close look at industry needs and a model curricula [PDF]

, 2004
Research endeavours in software development have found that failures and deficiencies of software systems are often rooted in the requirements activities undertaken.
Oliver Minor, Minor, Oliver, Minor, O., Armarego, J., Jocelyn Armarego, Armarego, Jocelyn   +5 more
core   +2 more sources

Eight years of delivering professional education and training for software engineering at Fraunhofer IESE: An experience report [PDF]

, 2022
S.131-138 : Ill., Lit.In this paper, we reflect on our experiences of delivering professional software engineering (SE) education and training over the course of the last eight years.
Waterson, P., Thomas, L., Trapp, S.
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Students’ and Instructors’ Perceptions of Five Different Active Learning Strategies Used to Teach Software Modeling

IEEE Access, 2019
Unified modeling language (UML) is a modeling standard in the software industry. However, students face difficulties when learning how to model complete and correct UML diagrams, in part because the traditional teacher-centered approach still dominates ...
Williamson Silva, Igor Steinmacher, Tayana Conte   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Enhancing software engineering education in higher education institutions through cloud-based learning tools: methodological and practical perspectives

Освітній вимір, 2023
Objective: This study aims to develop a comprehensive methodology for integrating cloud-based learning tools into software engineering education for students in higher education institutions (HEIs). Research tasks: The research encompasses exploring the
Andrii M. Striuk
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Experimental Evaluation of Using Gamification in Software Engineering Education in Software Requirements

CLEI Electronic Journal
Education in Software Engineering traditionally focuses on techniques used in the classroom that generate stress and disinterest in the topics taught; therefore, a significant challenge to the use of more effective and motivating teaching methods to ...
Sergio Galvan-Cruz, Mirna Muñoz, Jezreel Mejía, Adriana Peña, David Bonilla-Carranza   +4 more
doaj   +1 more source

Web Engineering as a Specialization of Software Engineering: Differences in Project Management Education [PDF]

Journal of Systemics, Cybernetics and Informatics, 2005
We present the motivation and our concept of introducing "Web Engineering" as a specialization of our "Software Engineering" curriculum. Our main focus lies on the differences in project management education for both areas as well as the necessary ...
Herwig Mayr
doaj