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Solid-Phase Synthesis of CD40L Mimetics
Synfacts, 2006The C3-symmetric molecule has been previously shown to mimic CD40 ligand (CD40L) homotrimers and to display effector functions. This molecule consists of a cyclic hexapeptide core containing the repetition of the D-Ala-L-Lys motif. The side chains of the lysine residues have been modified by appending the CD40L-derived sequence 143Lys-Gly-Tyr-Tyr146 ...
Alberto, Bianco +4 more
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Grafted supports in solid-phase synthesis
Biopolymers, 2000Solid-phase synthesis is greatly dependent on the solid phase. We are interested in the development of a "pellicular" type of solid support where a more mobile polymer is grafted to rigid plastics. Compared to low cross-linked microporous beads that dominate the field, this approach allows great flexibility of design, as plastics are available as ...
Rasoul, Firas +8 more
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Automated Solid-Phase Synthesis of Oligosaccharides
Science, 2001Traditionally, access to structurally defined complex carbohydrates has been very laborious. Although recent advancements in solid-phase synthesis have made the construction of complex oligosaccharides less tedious, a high level of technical expertise is still necessary to obtain the desired structures.
Plante, O., Palmacci, E., Seeberger, P.
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Automated Solid-Phase Peptide Synthesis
2019The development of solid-phase peptide synthesis by Bruce Merrifield paved the way for a synthesis carried out by machines. Automated peptide synthesis is a fast and convenient way of synthesizing many peptides simultaneously. This chapter tries to give a general guidance for the development of synthesis protocols for the peptide synthesizer.
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Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides.
Analytical Biochemistry, 1970E. Kaiser +3 more
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Solid phase peptide synthesis. I. the synthesis of a tetrapeptide
, 1963R. B. Merrifield
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Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids.
International journal of peptide & protein research, 2009G. Fields, R. Noble
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