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Solid-Phase Synthesis of CD40L Mimetics

Synfacts, 2006
The C3-symmetric molecule has been previously shown to mimic CD40 ligand (CD40L) homotrimers and to display effector functions. This molecule consists of a cyclic hexapeptide core containing the repetition of the D-Ala-L-Lys motif. The side chains of the lysine residues have been modified by appending the CD40L-derived sequence 143Lys-Gly-Tyr-Tyr146 ...
Alberto, Bianco   +4 more
openaire   +2 more sources

Grafted supports in solid-phase synthesis

Biopolymers, 2000
Solid-phase synthesis is greatly dependent on the solid phase. We are interested in the development of a "pellicular" type of solid support where a more mobile polymer is grafted to rigid plastics. Compared to low cross-linked microporous beads that dominate the field, this approach allows great flexibility of design, as plastics are available as ...
Rasoul, Firas   +8 more
openaire   +2 more sources

Automated Solid-Phase Synthesis of Oligosaccharides

Science, 2001
Traditionally, access to structurally defined complex carbohydrates has been very laborious. Although recent advancements in solid-phase synthesis have made the construction of complex oligosaccharides less tedious, a high level of technical expertise is still necessary to obtain the desired structures.
Plante, O., Palmacci, E., Seeberger, P.
openaire   +3 more sources

Automated Solid-Phase Peptide Synthesis

2019
The development of solid-phase peptide synthesis by Bruce Merrifield paved the way for a synthesis carried out by machines. Automated peptide synthesis is a fast and convenient way of synthesizing many peptides simultaneously. This chapter tries to give a general guidance for the development of synthesis protocols for the peptide synthesizer.
openaire   +2 more sources

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides.

Analytical Biochemistry, 1970
E. Kaiser   +3 more
semanticscholar   +1 more source

Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids.

International journal of peptide & protein research, 2009
G. Fields, R. Noble
semanticscholar   +1 more source

Solid-Phase Synthesis

2005
S. Braverman, M. Cherkinsky, M. L. Birsa
openaire   +2 more sources

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