Results 51 to 60 of about 1,773,765 (367)
Novel Solution- and Solid-Phase Syntheses of Heterocyclic Systems
CHIMIA, 2003 Heterocyclic compounds are an attractive source of screening library structures because they possess varied structural diversity and can exhibit potent biological activity.
Gaelle Cabon +4 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
N-Butylpyrrolidinone as Alternative Solvent for Solid-Phase Peptide Synthesis
, 2018 By means of a systematic approach, several green solvent candidates were tested for their feasibility to replace the reprotoxic dimethylformamide (DMF) as a solvent used in solid-phase peptide synthesis (SPPS).
John Lopez +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Solid‐Phase Synthesis of Oligosaccharides
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Diederichsen, Ulf, Wagner, Thomas
openaire +4 more sources
Solid Phase Synthesis of a Metronidazole Oligonucleotide Conjugate
Molecules, 2006 Direct, solid phase synthesis of an oligonucleotide conjugate of the antibioticdrug metronidazole was accomplished by the phosphoramidite method. Removal ofprotecting groups and cleavage from the controlled pore glass (CPG) solid support wassuccessful ...
William Fraser +2 more
doaj +1 more source
Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids [PDF]
, 2012 A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good ...
Grubbs, Robert H. +3 more
core +1 more source
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Fragment synthesis of disulfide-containing peptides
MethodsX, 2020 A new strategy for solid phase peptide synthesis in the fragment synthesis based on the use of 2-Cl-trityl resin as carrier to obtain protected peptide-resin and Rink Amide Resin, HOBT/HBTU or PyBOP/DIPEA or HATU/DIPEA as the coupling method is described.
Yuxuan Dai +3 more
doaj
Organic Synthesis on Solid Phase. (Supports, Linkers, Reactions)
Molecules, 2001 n ...
Florencio Zaragoza Dörwald
doaj +1 more source